Search Results - "Reusch, H. P."

Acidic pre‐conditioning suppresses apoptosis and increases expression of Bcl‐xL in coronary endothelial cells under simulated ischaemia by Kumar, S., Reusch, H. P., Ladilov, Y.

“…Ischaemic pre‐conditioning has a powerful protective potential against ischaemia‐induced cell death, and acidosis is an important featur of ischaemia and can…”
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SLC4A7 sodium bicarbonate co-transporter controls mitochondrial apoptosis in ischaemic coronary endothelial cells by KUMAR, Sanjeev, FLACKE, Jan-Paul, KOSTIN, Sawa, APPUKUTTAN, Avinash, REUSCH, Hans Peter, LADILOV, Yury

“…Bicarbonate transport has been shown to participate in apoptosis under ischaemic stress. However, the precise transporting mechanisms involved in ischaemic…”
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Cytotoxic activity of nemorosone in neuroblastoma cells by Díaz‐Carballo, D., Malak, S., Bardenheuer, W., Freistuehler, M., Reusch, H. P.

“…Neuroblastoma is the second most common solid tumour during childhood, characterized by rapid disease progression. Most children with metastasized…”
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Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture by Abdallah, Y, Wolf, C, Meuter, K, Piper, H.M, Reusch, H.P, Ladilov, Y

“…Abstract Ischemic preconditioning has a powerful protective potential against a reperfusion-induced injury of the post-ischemic myocardium. Cardiomyocyte…”
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Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis by KÖHLER, Ralf, WULFF, Heike, REAL, Robert, BORNER, Klaus, BRAKEMEIER, Susanne, ORZECHOWSKI, Hans-Dieter, REUSCH, Hans-Peter, PAUL, Martin, CHANDY, K. George, HOYER, Joachim, EICHLER, Ines, KNEIFEL, Marlene, NEUMANN, Daniel, KNORR, Andrea, GRGIC, Ivica, KÄMPFE, Doris, SI, Han, WIBAWA, Judith

“…Angioplasty stimulates proliferation and migration of vascular smooth muscle cells (VSMC), leading to neointimal thickening and vascular restenosis. In a rat…”
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Nemorosone blocks proliferation and induces apoptosis in leukemia cells by Díaz-Carballo, D, Malak, S, Freistühler, M, Elmaagacli, A, Bardenheuer, W, Reusch, H P

“…This work is aimed at characterizing nemorosone, isolated from Clusia rosea, as a potential antileukemic agent. In addition, we analyzed its influence on…”
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Osmotic activation of a Na(+)-dependent Cl-/HCO3- exchanger by Reusch, H P, Lowe, J, Ives, H E

“…In many systems, osmotically induced cell shrinkage activates the Na+/H+ exchanger. To assess the role of H(+)-extruding transporters in the response to…”
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Regulation of Raf by Akt Controls Growth and Differentiation in Vascular Smooth Muscle Cells by Reusch, H. Peter, Zimmermann, Sven, Schaefer, Michael, Paul, Martin, Moelling, Karin

“…The stimulation of platelet-derived growth factor (PDGF) receptors shifts vascular smooth muscle (VSM) cells toward a more proliferative phenotype. Thrombin…”
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Activation of Na+/H+ exchange by platelet-derived growth factor involves phosphatidylinositol 3'-kinase and phospholipase C gamma by Ma, Y H, Reusch, H P, Wilson, E, Escobedo, J A, Fantl, W J, Williams, L T, Ives, H E

“…The effect of site-specific mutations in the mouse platelet-derived growth factor (PDGF) beta-receptor on activation of the Na+/H+ exchanger was examined in…”
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Enhanced Na(+)-H+ exchanger activity and NHE-1 mRNA levels in human lymphocytes during metabolic acidosis by Quednau, B, Rosskopf, D, Reusch, H P, Luft, F C, Siffert, W

“…It has recently been demonstrated that uremic metabolic acidosis and experimental metabolic acidosis caused by ingestion of ammonium chloride coincide with…”
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Mucronulatol from Caribbean propolis exerts cytotoxic effects on human tumor cell lines by Diaz-Carballo, D, Freistã Hler, M, Malak, S, Bardenheuer, W, Reusch, H P

“…Mucronulatol is one of the most cytotoxic substances present in Caribbean propolis. This work aimed at initially characterizing the biological effects of…”
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Increased concentrations of omega-3 fatty acids in milk and platelet rich plasma of grass-fed cows by Hebeisen, D F, Hoeflin, F, Reusch, H P, Junker, E, Lauterburg, B H

“…Epidemiological data indicate that omega-3 fatty acids protect from cardiovascular diseases and hyperlipidemia. Cold water fish is the major recognized source…”
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Na+/H+ exchange in human lymphocytes and platelets in chronic and subacute metabolic acidosis by REUSCH, H. P, REUSCH, R, ROSSKOPF, D, SIFFERT, W, MANN, J. F. E, LUFT, F. C

“…The effect of acid-base disturbances on sodium/proton (Na+/H+) exchange has been examined in animal models; however, few data are available from human studies…”
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Light-chain-induced renal tubular acidosis: effect of sodium bicarbonate on sodium-proton exchange by Reusch, H P, Mann, J F, Mihatch, M J, Siffert, W, Luft, F C

“…We measured sodium-proton (Na+/H+) exchange in lymphocytes and platelets of a 46-year-old woman with the adult Fanconi syndrome before, during, and after…”
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ERK1/2-Dependent Contractile Protein Expression in Vascular Smooth Muscle Cells by Schauwienold, Dag, Plum, Claudia, Helbing, Thomas, Voigt, Philipp, Bobbert, Thomas, Hoffmann, Dorett, Paul, Martin, Reusch, Hans Peter

“…ABSTRACT—In vivo, vascular smooth muscle (VSM) cells change their contractile phenotype toward a more proliferative phenotype during the pathogenesis of…”
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Activation of JNK/SAPK and ERK by Mechanical Strain in Vascular Smooth Muscle Cells Depends on Extracellular Matrix Composition by Reusch, H.Peter, Chan, Germaine, Ives, Harlan E., Nemenoff, Raphael A.

“…Application of cyclic mechanical strain to vascular smooth muscle (VSM) cells elicits distinct cellular responses depending on extracellular matrix…”
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Potential effect of metabolic acidosis on beta 2-microglobulin generation: in vivo and in vitro studies by Sonikian, M, Gogusev, J, Zingraff, J, Loric, S, Quednau, B, Bessou, G, Siffert, W, Drüeke, T B, Reusch, H P, Luft, F C

“…Beta 2-microglobulin (beta 2M) is responsible for dialysis-associated amyloidosis. Level of beta 2M in plasma increase during chronic renal failure; however,…”
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Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma by Brock, Carsten, Schaefer, Michael, Reusch, H Peter, Czupalla, Cornelia, Michalke, Manuela, Spicher, Karsten, Schultz, Günter, Nürnberg, Bernd

“…Receptor-regulated class I phosphoinositide 3-kinases (PI3K) phosphorylate the membrane lipid phosphatidylinositol (PtdIns)-4,5-P2 to PtdIns-3,4,5-P3. This, in…”
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Ca super(2+)-controlled competitive diacylglycerol binding of protein kinase C isoenzymes in living cells by Lenz, J C, Reusch, H P, Albrecht, N, Schultz, G, Schaefer, M

“…The cellular decoding of receptor-induced signaling is based in part on the spatiotemporal activation pattern of PKC isoforms. Because classical and novel PKC…”
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Gbeta gamma mediate differentiation of vascular smooth muscle cells by Reusch, H P, Schaefer, M, Plum, C, Schultz, G, Paul, M

“…Proliferation and subsequent dedifferentiation of vascular smooth muscle (VSM) cells contribute to the pathogenesis of atherosclerosis and postangioplastic…”
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