Search Results - "Reus, V."

Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response by Wolkowitz, O M, Mellon, S H, Epel, E S, Lin, J, Reus, V I, Rosser, R, Burke, H, Compagnone, M, Nelson, J C, Dhabhar, F S, Blackburn, E H

“…Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. When telomeres critically shorten, cells become susceptible to…”
Get full text

Immunogenicity and Smoking-Cessation Outcomes for a Novel Nicotine Immunotherapeutic by Hatsukami, DK, Jorenby, DE, Gonzales, D, Rigotti, NA, Glover, ED, Oncken, CA, Tashkin, DP, Reus, VI, Akhavain, RC, Fahim, REF, Kessler, PD, Niknian, M, Kalnik, MW, Rennard, SI

“…NicVAX, a nicotine vaccine (3′AmNic‐rEPA), has been clinically evaluated to determine whether higher antibody (Ab) concentrations are associated with higher…”
Get full text

Dysregulated relationship of inflammation and oxidative stress in major depression by Rawdin, B.J, Mellon, S.H, Dhabhar, F.S, Epel, E.S, Puterman, E, Su, Y, Burke, H.M, Reus, V.I, Rosser, R, Hamilton, S.P, Nelson, J.C, Wolkowitz, O.M

“…Highlight ► The relationship of inflammation to oxidation may be disturbed in untreated major depression; this may reflect or contribute to increased risk of…”
Get full text

The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response by Giacomini, K M, Brett, C M, Altman, R B, Benowitz, N L, Dolan, M E, Flockhart, D A, Johnson, J A, Hayes, D F, Klein, T, Krauss, R M, Kroetz, D L, McLeod, H L, Nguyen, A T, Ratain, M J, Relling, M V, Reus, V, Roden, D M, Schaefer, C A, Shuldiner, A R, Skaar, T, Tantisira, K, Tyndale, R F, Wang, L, Weinshilboum, R M, Weiss, S T, Zineh, I

“…The NIH Pharmacogenetics Research Network (PGRN) is a collaborative group of investigators with a wide range of research interests, but all attempting to…”
Get full text

Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines by Reus, V I, Smith, B J

“…Nicotine addiction is a complex, chronic condition with physiological and psychological/behavioural aspects that make smoking cessation extremely difficult…”
Get more information

Alterations in leukocyte transcriptional control pathway activity associated with major depressive disorder and antidepressant treatment by Mellon, S H, Wolkowitz, O M, Schonemann, M D, Epel, E S, Rosser, R, Burke, H B, Mahan, L, Reus, V I, Stamatiou, D, Liew, C -C, Cole, S W

“…Major depressive disorder (MDD) is associated with a significantly elevated risk of developing serious medical illnesses such as cardiovascular disease, immune…”
Get full text

Double-Blind Treatment of Major Depression With Dehydroepiandrosterone by Wolkowitz, Owen M., Reus, Victor I., Keebler, Audrey, Nelson, Nicola, Friedland, Mirit, Brizendine, Louann, Roberts, Eugene

“…OBJECTIVE: This study was designed to assess possible antidepressant effects of dehydroepiandrosterone (DHEA), an abundant adrenocortical hormone in humans…”
Get full text

Self injurious behaviour in Tourette syndrome: correlates with impulsivity and impulse control by Mathews, C A, Waller, J, Glidden, D, Lowe, T L, Herrera, L D, Budman, C L, Erenberg, G, Naarden, A, Bruun, R D, Freimer, N B, Reus, V I

“…Background: Self injurious behaviour (SIB), the deliberate, repetitive infliction of self harm, is present in a wide variety of neuropsychiatric disorders,…”
Get full text

DHEA treatment of Alzheimer's disease: A randomized, double-blind, placebo-controlled study by WOLKOWITZ, O. M, KRAMER, J. H, DE SOUZA, E, SADOWSKY, C, ROBERTS, E, REUS, V. I, COSTA, M. M, YAFFE, K, WALTON, P, RASKIND, M, PESKIND, E, NEWHOUSE, P, SACK, D

“…To compare the efficacy and tolerability of dehydroepiandrosterone (DHEA) vs placebo in AD. Fifty-eight subjects with AD were randomized to 6 month's treatment…”
Get full text

Therapeutic Drug Monitoring of Nortriptyline in Smoking Cessation: A Multistudy Analysis by Mooney, ME, Reus, VI, Gorecki, J, Hall, SM, Humfleet, GL, Muñoz, RF, Delucchi, K

“…Multiple, controlled clinical trials support the efficacy of nortriptyline as a smoking cessation agent. Although therapeutic plasma nortriptyline…”
Get full text

Selective Alteration of Personality and Social Behavior by Serotonergic Intervention by Knutson, Brian, Wolkowitz, Owen M., Cole, Steve W., Chan, Theresa, Moore, Elizabeth A., Johnson, Ronald C., Terpstra, Jan, Turner, Rebecca A., Reus, Victor I.

“…OBJECTIVE: The authors sought to test the causal hypothesis that serotonergic function modulates aspects of the normal spectrum of individual differences in…”
Get full text

Dehydroepiandrosterone (DHEA) treatment of depression by Wolkowitz, Owen M., Reus, Victor I., Roberts, Eugene, Manfredi, Francesca, Chan, Theresa, Raum, William J., Ormiston, Susan, Johnson, Ronald, Canick, Jonathan, Brizendine, Louann, Weingartner, Herbert

“…Dehydroepiandrosterone (DHEA) and its sulfate, DHEA-S, are plentiful adrenal steroid hormones that decrease with aging and may have significant…”
Get full text

169. Inflammatory and oxidative stress are highly correlated in unmedicated major depression by Rawdin, B, Mellon, S, Dhabhar, F, Epel, E, Su, Y, Rosser, R, Burke, H, Reus, V, Hamilton, S, Nelson, C, Wolkowitz, O

“…Inflammation and oxidative stress have been implicated both separately and jointly in aging and the pathophysiology of many diseases. This study examines the…”
Get full text

Antiglucocorticoid treatment of depression: double-blind ketoconazole by Wolkowitz, Owen M, Reus, Victor I, Chan, Theresa, Manfredi, Francesca, Raum, William, Johnson, Ron, Canick, Jonathan

“…Background: Hypercortisolemia is frequently observed in major depression but its pathophysiologic significance is unknown. In patients in whom hypercortisolism…”
Get full text

Genome-wide linkage scan of bipolar disorder in a Colombian population isolate replicates Loci on chromosomes 7p21-22, 1p31, 16p12 and 21q21-22 and identifies a novel locus on chromosome 12q by Kremeyer, B, García, J, Müller, H, Burley, M W, Herzberg, I, Parra, M V, Duque, C, Vega, J, Montoya, P, López, M C, Bedoya, G, Reus, V, Palacio, C, López, C, Ospina-Duque, J, Freimer, N B, Ruiz-Linares, A

“…Bipolar disorder (BP) is a severe psychiatric illness, characterised by alternating episodes of depression and mania, which ranks among the top ten causes of…”
Get more information

Antiglucocorticoid drugs in the treatment of depression by Reus, V I, Wolkowitz, O M

“…A confluence of evidence indicates that prolonged elevation in gluco-corticoid level may result in disturbances of mood and cognition. In Cushing's syndrome,…”
Get more information

Olanzapine: a novel atypical neuroleptic agent by Reus, V I

Get more information

Nicotine, Negative Affect, and Depression by Hall, Sharon M, Muñoz, Ricardo F, Reus, Victor I, Sees, Karen L

“…Depression, whether conceptualized as a trait, symptom, or as a diagnosable disorder, is overrepresented among smokers. Depressed smokers appear to experience…”
Get full text

Treatment of depression with antiglucocorticoid drugs by Wolkowitz, O M, Reus, V I

“…The theoretical and empirical rationales for the potential therapeutic use of antiglucocorticoid agents in the treatment of depression are reviewed. Individual…”
Get full text

Cognitive-Behavioral Intervention Increases Abstinence Rates for Depressive-History Smokers by Hall, Sharon M, Muñoz, Ricardo F, Reus, Victor I

“…This article describes the test of the hypothesis that a cognitive-behavioral mood management intervention would be effective for smokers with a history of…”
Get full text