Search Results - "Reuhl, K.R."

Neurons derived from P19 embryonal carcinoma cells have varied morphologies and neurotransmitters by Staines, W A, Morassutti, D J, Reuhl, K R, Ally, A I, McBurney, M W

“…Treatment of P19 embryonal carcinoma cells with retinoic acid induces their differentiation into a population of cells consisting of neurons and other cell…”
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Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s) by Garbuzenko, O.B, Ivanova, V, Kholodovych, V, Reimer, D.C, Reuhl, K.R, Yurkow, E, Adler, D, Minko, T

“…Abstract Inhalation delivery of prostaglandin E (PGE2) in combination with selected siRNA(s) was proposed for the efficient treatment of idiopathic pulmonary…”
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The effect of glutathione depletion on methyl mercury-induced microtubule disassembly in cultured embryonal carcinoma cells by Graff, R D, Philbert, M A, Lowndes, H E, Reuhl, K R

“…Microtubule (MT) assembly and stability are thought to be dependent on intracellular glutathione for the maintenance of critical sulfhydryl groups. Since…”
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Trimethyltin-induced alterations in behavior are linked to changes in PSA-NCAM expression by Halladay, A.K., Wilson, D.T., Wagner, G.C., Reuhl, K.R.

“…The neurotoxic heavy metal trimethyltin (TMT) primarily damages neurons of the hippocampus and limbic areas of the temporal lobe, and causes a dose-dependent…”
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Developmental lead exposure disturbs expression of synaptic neural cell adhesion molecules in herring gull brains by Dey, P.M., Burger, J., Gochfeld, M., Reuhl, K.R.

“…Neurobehavioral testing of herring gull chicks ( Larus argentatus) in both laboratory and field studies indicates that lead exposure during critical periods of…”
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Methylmercury Alters Eph and Ephrin Expression During Neuronal Differentiation of P19 Embryonal Carcinoma Cells by Wilson, D.T., Polunas, M.A., Zhou, R., Halladay, A.K., Lowndes, H.E., Reuhl, K.R.

“…Developmental exposure to methylmercury (MeHg) induces a spectrum of neurological impairment characterized by cognitive disturbance, sensory/motor deficit, and…”
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The effects of plant-incorporated methylmercury on its distribution, excretion and demethylation patterns in the rat by Czuba, M, Komsta-Szumska, E, Mortimer, D C, Reuhl, K R

“…Rats were dosed once per os with either plant-incorporated or solution-radioactive methylmercury (MeHg). While whole-body retention did not change, the…”
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Effect of selenium on distribution, demethylation, and excretion of methylmercury by the guinea pig by Komsta-Szumska, E, Reuhl, K R, Miller, D R

“…The influence of selenium on methylmercury excretion, organ and subcellular distribution, and demethylation was studied in the guinea pig at different times…”
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Altered Sensitivity of Posttranslationally Modified Microtubules to Methylmercury in Differentiating Embryonal Carcinoma-Derived Neurons by Graff, R.D., Falconer, M.M., Brown, D.L., Reuhl, K.R.

“…The effects of methylmercury (MeHg) on microtubules (MTs) in differentiating neurons derived from retinoic acid-induced embryonal carcinoma (EC) cells in…”
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Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-phthaldialdehyde-induced histofluorescence by Philbert, M A, Beiswanger, C M, Waters, D K, Reuhl, K R, Lowndes, H E

“…Differences in the cellular distribution of antioxidant defense mechanisms in heterogeneous tissue such as the nervous system are likely critical determinants…”
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Involvement of nonparenchymal cells in oxygen-dependent hepatic injury by allyl alcohol by Przybocki, J M, Reuhl, K R, Thurman, R G, Kauffman, F C

“…Allyl alcohol injury to hepatocytes in the perfused liver is oxygen-dependent. It is not known if this injury involves direct action of allyl alcohol on…”
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Selective loss of the 180-kDa form of the neural cell adhesion molecule in hippocampus and cerebellum of the adult mouse following trimethyltin administration by Dey, P M, Graff, R D, Lagunowich, L A, Reuhl, K R

“…The neural cell adhesion molecule (NCAM), a membrane glycoprotein which plays critical roles in cell-cell recognition and in the maintenance of…”
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Effects of benzene metabolite treatment on granulocytic differentiation and DNA adduct formation in HL-60 cells by HEDLI, C. C, RAO, N. R, REUHL, K. R, WITMER, C. M, SNYDER, R

“…Reactive metabolites of benzene (BZ) play important roles in BZ-induced hematotoxicity. Although reactive metabolites of BZ covalently bind to DNA, the…”
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Cell lines with developmental potential restricted to mesodermal lineages isolated from differentiating cultures of pluripotential P19 embryonal carcinoma cells by Rudnicki, M A, Reuhl, K R, McBurney, M W

“…Embryonal carcinoma (EC) cells are developmentally pluripotential cells which can be induced to differentiate in cell culture to form a wide variety of cell…”
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Synergistic neurotoxic effects of styrene oxide and acrylamide: glutathione-independent necrosis of cerebellar granule cells by Beiswanger, C M, Mandella, R D, Graessle, T R, Reuhl, K R, Lowndes, H E

“…Conjugation with glutathione (GSH) is a mechanism of detoxification of acrylamide (ACR); hence, prior depletion of GSH might be expected to exacerbate ACR's…”
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3-Nitropropionic acid toxicity in cultured murine embryonal carcinoma cells by Pass, M A, Carlisle, C H, Reuhl, K R

“…The morphologic and histochemical effects of 3-nitropropionic acid (NPA) were examined in cultured murine embryonal carcinoma cells. NPA caused a…”
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Neuropathology of trimethyltin intoxication. I. Light microscopy study by Chang, L W, Tiemeyer, T M, Wenger, G R, McMillan, D E, Reuhl, K R

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Neuropathology of trimethyltin intoxication. II. Electron microscopic study on the hippocampus by Chang, L W, Tiemeyer, T M, Wenger, G R, McMillan, D E, Reuhl, K R

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Demethylation and excretion of methyl mercury by the guinea pig by Komsta-Szumska, E, Czuba, M, Reuhl, K R, Miller, D R

“…Female guinea pigs were dosed po with 1.0 mg CH3 203Hg/kg as methylmercuric chloride, 10 times over a 3-week period. Tissue distribution, excretion, and…”
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Degenerative changes in the developing nervous system as a result of in utero exposure to methylmercury by Chang, L W, Reuhl, K R, Lee, G W

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