Search Results - "Reuber, M. D"

Liver Tumors Induced in Rats by Oral Administration of the Antihistaminic Methapyrilene Hydrochloride by Lijinsky, W., Reuber, M. D., B.-N. Blackwell

“…The antihistaminic over-the-counter drug methapyrilene hydrochloride, mixed with food at a concentration of 0.1 percent, was administered to 50 male and 50…”
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Carcinogenicity of captan by Reuber, M D

“…Two studies on the carcinogenicity of the fungicide captan in animals were reviewed. The results and conclusions, which were based on my examination of the…”
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Dose response studies of carcinogenesis in rats by nitrosodiethylamine by Lijinsky, W, Reuber, M D, Riggs, C W

“…A dose-response study was conducted in Fischer rats with nitrosodiethylamine, which was administered in regulated amounts as a solution in drinking water…”
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Potent carcinogenicity of nitrosodiethanolamine in rats by Lijinsky, W, Reuber, M. D, Manning, W. B

“…Nitrosodiethanolamine is found in synthetic cutting oils and in many cosmetic preparations and is probably the N-nitroso compound to which human exposure is…”
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Organ-specific carcinogenesis in rats by methyl- and ethylazoxyalkanes by LIJINSKY, W, SAAVEDRA, J. E, REUBER, M. D

“…Azoxyalkanes are isomeric with nitrosodialkylamines and could be similar in their biochemical and biological actions. To compare the structure-activity…”
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Carcinogenicity and toxicity of malathion and malaoxon by Reuber, M D

“…Malathion and its oxygen analogue, malaoxon, are carcinogenic in Osborne-Mendel and Fischer-344 rats. Benign and malignant neoplasms at all sites were…”
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Atrial thrombosis involving the heart of F-344 rats ingesting quinacrine hydrochloride by REUBER, M. D, LIJINSKY, W

“…Quinacrine hydrochloride is toxic for the heart of F-344 rats. Rats treated with 500 ppm quinacrine hydrochloride in the diet all developed a high incidence of…”
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Carcinogenesis in rats by nitrosodimethylamine and other nitrosomethylalkylamines at low doses by Lijinsky, W, Reuber, M D

“…Four nitrosomethylalkylamines were given to F344 rats in drinking water at concentrations of 0.22 mM or less. The total doses delivered to each animal were 0.5…”
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Neoplasms of the skin and other organs observed in Swiss mice treated with nitrosoalkylureas by LIJINSKY, W, REUBER, M. D

“…A number of nitrosoalkylureas, nitrosoalkylcarbamates, and chlorinated nitrosotrialkylureas were painted twice a week on the skin of female Swiss mice at a…”
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Carcinogenesis in Fischer rats by nitrosodipropylamine, nitrosodibutylamine and nitrosobis(2-oxopropyl)amine given by gavage by Lijinsky, W, Reuber, M D

“…Nitrosodi-n-propylamine, nitrosodi-n-butylamine and the ketone nitrosobis(2-oxopropyl)amine were administered by gavage to F344 rats at doses of 1 and 2 mmol…”
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Dose-response study with N-nitrosodiethanolamine in F344 rats by Lijinsky, W, Reuber, M D

“…A dose-response study of the carcinogenicity of N-nitrosodiethanolamine was conducted in F344 rats. The nitrosamine was administered in drinking-water at a…”
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Carcinogenicity of heptachlor and heptachlor epoxide by Reuber, M D

“…Heptachlor and its metabolite heptachlor epoxide are unequivocally carcinogenic in rats and mice. The chemicals induced carcinomas of the liver, which were…”
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Carcinogenesis in rats by some hydroxylated acyclic nitrosamines by Lijinsky, W, Saavedra, J E, Reuber, M D

“…A comparison was made of the carcinogenic effectiveness of five hydroxylated nitrosodialkylamines given to female F344 rats in drinking water…”
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The effect of deuterium substitution on carcinogenesis by azoxymethane by Lijinsky, W, Reuber, M D, Saavedra, J E

“…Azoxymethane was synthesized labeled with deuterium in one or other of the two methyl groups. Groups of 20 male F344 rats were given either 4 mg or 1 mg per…”
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Comparison of nitrosocimetidine with nitrosomethylnitroguanidine in chronic feeding tests in rats by LIJINSKY, W, REUBER, M. D

“…N-Nitrosocimetidine, a nitroso derivative of the drug cimetidine, was given to groups of 20 male and 20 female rats in drinking water at a concentration of 0.5…”
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Carcinogenicity and toxicity of methoxychlor [Insecticide] by Reuber, Melvin Dwaine

“…Methoxychlor is carcinogenic for the liver of C3H and BALB/c mice and Osborne-Mendel rats, and possibly for the liver of dogs. Methoxychlor is also…”
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Comparative carcinogenesis by some aliphatic nitrosamines in Fischer rats by Lijinsky, W, Reuber, M D

“…The carcinogenic effectiveness of 5 simple aliphatic nitrosamines was compared by feeding to groups of 20 Fischer rats in drinking water…”
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Chronic carcinogenesis studies of acrolein and related compounds by Lijinsky, W, Reuber, M D

“…Acrolein and two of its more stable derivatives, the oxime and the diethylacetal, and the related allyl alcohol were given in drinking water to groups of 20…”
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Benign chordoma (sacrococcygeal) in the rat: a light and electron microscopic study by Reuber, M D, Reznik-Schüller, H M

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Carcinogenicity of methylated nitrosopiperazines in rats and hamsters by Lijinsky, W, Knutsen, G M, Reuber, M D

“…A comparison has been made of the carcinogenic activities of dinitroso-2,6-dimethylpiperazine (Me2DNP) and nitroso-3-4,5-trimethylpiperazine (Me3NP) in F344…”
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