Search Results - "Retzinger, Gregory S"
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The Acari Hypothesis, V: deciphering allergenicity
Published in Frontiers in allergy (01-11-2024)“…The Acari Hypothesis posits that acarians, i.e., mites and ticks, are operative agents of allergy. It derived from observations that allergens are molecular…”
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The Acari Hypothesis, IV: revisiting the role of hygiene in allergy
Published in Frontiers in allergy (10-07-2024)“…Allergy and its manifestations were first appreciated in the 1870 s. Today, the mechanism by which specific substances elicit allergic reactions remains poorly…”
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The Acari Hypothesis, III: Atopic Dermatitis
Published in Pathogens (Basel) (23-09-2022)“…Atopic dermatitis is a chronic relapsing dermatopathology involving IgE against allergenic materials present on mammalian epithelial surfaces. Allergens are as…”
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The Acari Hypothesis, II: Interspecies Operability of Pattern Recognition Receptors
Published in Pathogens (Basel) (21-09-2021)“…Hypersensitivity to galactose-α-1,3-galactose (α-gal) is an informative example of a pathologic IgE-mediated process. By way of their saliva, ticks are able to…”
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Competing Bioaerosols May Influence the Seasonality of Influenza-Like Illnesses, including COVID-19. The Chicago Experience
Published in Pathogens (Basel) (16-09-2021)“…Data from Chicago confirm the end of flu season coincides with the beginning of pollen season. More importantly, the end of flu season also coincides with…”
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Mites, ticks, anaphylaxis and allergy: The Acari hypothesis
Published in Medical hypotheses (01-11-2020)“…Anaphylaxis is a poorly understood immune process in which a Th2-/IgE-mediated adaptive response commandeers cellular machinery, typically reserved for defense…”
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TLR4 involvement in COVID-19 predicts a seasonal risk of Aspergillus superinfection: A call for vigilance
Published in Medical hypotheses (01-09-2021)Get full text
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The Acari Hypothesis, VI: human sebum and the cutaneous microbiome in allergy and in lipid homeostasis
Published in Frontiers in allergy (21-11-2024)“…The Acari Hypothesis posits that acarians, i.e., mites and ticks, are causative agents of IgE-mediated conditions. This report further develops The Hypothesis,…”
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Estimate of benefit attributable to wearing masks in Chicago during the early days of the pandemic
Published in Medical hypotheses (01-11-2021)Get full text
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10
A turbidimetric method for measuring the activity of trypsin and its inhibition
Published in Analytical biochemistry (01-04-2006)“…Microscopic poly(styrene-divinylbenzene) beads coated with a monomolecular film of fibrinogen agglutinate when stirred in the presence of thrombin, a…”
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Fibrinogen-Coated Droplets of Olive Oil for Delivery of Docetaxel to a Fibrin(ogen)-Rich Ascites Form of a Murine Mammary Tumor
Published in Clinical cancer research (15-10-2004)“…Micronized droplets of olive oil loaded with docetaxel and coated with functional fibrinogen were administered intraperitoneally to mice bearing the…”
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Adsorption and Coagulability of Fibrinogen on Atheromatous Lipid Surfaces
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-1995)“…Fibrinogen, the precursor of the blood clot matrix and a major constituent of atherosclerotic lesions, is shown to adsorb with high affinity to hydrophobic…”
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Adsorbed fibrinogen regulates the behavior of human dendritic cells in a CD18-dependent manner
Published in Experimental and molecular pathology (01-04-2008)“…The involvement of fibrinogen in inflammation has been considered by many, but the roles of the protein in that process have yet to be fully elucidated. The…”
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Extracellular transport of cell-size particles and tumor cells by dendritic cells in culture
Published in Experimental and molecular pathology (01-12-2013)“…Many particulate materials of sizes approximating that of a cell disseminate after being introduced into the body. While some move about within phagocytic…”
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Block and Graft Copolymers of Poly(ethylene glycol) and Poly(dimethylsiloxane) for Blood Contacting Biomedical Materials Applications
Published in SILICON (01-10-2012)“…The incorporation of both hydrophobic and hydrophilic groups into a synthetic polymer is a potent way of controlling its surface and interfacial properties…”
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Preparation, characterization, and preliminary application of fibrinogen-coated olive oil droplets for the targeted delivery of docetaxel to solid malignancies
Published in Cancer research (Chicago, Ill.) (01-11-2003)“…Micronized droplets of olive oil loaded with docetaxel (1.0 mg.ml(-1)) and coated with fibrinogen were prepared and then characterized for physicochemical and…”
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Mitogenicity of a spread film of monophosphoryl lipid A
Published in Experimental and molecular pathology (01-10-2005)“…When spread at the air–water interface, monophosphoryl lipid A (MPLA) forms stable insoluble monolayers that collapse at ∼55 dyn/cm. At collapse, the exclusion…”
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Fibrinogen-coated chylomicrons in gastrointestinal lymph: a new rationale regarding the arterial deposition of postprandial lipids
Published in Medical hypotheses (01-12-2002)“…The recent discovery that fibrinogen binds to chylomicrons in gastrointestinal lymph has prompted a new rationale regarding the arterial deposition of…”
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Ordering of Poly(ethylene oxide)/Poly(propylene oxide) Triblock Copolymers in Condensed Films
Published in Langmuir (30-03-1999)“…Triblock copolymers of the form PEOαPPOβPEOα [where PEO is poly(ethylene oxide) and PPO is poly(propylene oxide)] form stable insoluble monolayers at both the…”
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The Role of Surface in the Pathogenesis and Treatment of COVID-19
Published in COVID (01-10-2021)“…Recently, an inverse relationship between incidence of COVID-19 and seasonal aerosolization of mold spores was demonstrated. Analyses of that relationship…”
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