Search Results - "Reto S. Wijker"
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Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
Published in Nature communications (24-09-2020)“…Non-invasively probing metabolites within single live cells is highly desired but challenging. Here we utilize Raman spectro-microscopy for spatial mapping of…”
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2
Biosynthetic and catabolic pathways control amino acid δ2H values in aerobic heterotrophs
Published in Frontiers in microbiology (05-04-2024)“…The hydrogen isotope ratios (δ 2 H AA values) of amino acids in all organisms are substantially fractionated relative to growth water. In addition, they…”
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3
Isotope Effects as New Proxies for Organic Pollutant Transformation
Published in Chimia (01-11-2014)“…Assessing the pathways and rates of organic pollutant transformation in the environment is a major challenge due to co-occurring transport and degradation…”
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4
Hydrogen isotope fractionation is controlled by CO 2 in coccolithophore lipids
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2024)“…Hydrogen isotope ratios (δ H) represent an important natural tracer of metabolic processes, but quantitative models of processes controlling H-fractionation in…”
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5
Hydrogen isotope fractionation is controlled by CO2 in coccolithophore lipids
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2024)“…Hydrogen isotope ratios (δ2H) represent an important natural tracer of metabolic processes, but quantitative models of processes controlling H-fractionation in…”
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6
2H/1H variation in microbial lipids is controlled by NADPH metabolism
Published in Proceedings of the National Academy of Sciences - PNAS (18-06-2019)“…The hydrogen-isotopic compositions (2H/1H ratios) of lipids in microbial heterotrophs are known to vary enormously, by at least 40% (400‰) relative. This is…”
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7
2 H/ 1 H variation in microbial lipids is controlled by NADPH metabolism
Published in Proceedings of the National Academy of Sciences - PNAS (18-06-2019)“…The hydrogen-isotopic compositions ( H/ H ratios) of lipids in microbial heterotrophs are known to vary enormously, by at least 40% (400‰) relative. This is…”
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8
Isotopic Analysis of Oxidative Pollutant Degradation Pathways Exhibiting Large H Isotope Fractionation
Published in Environmental science & technology (03-12-2013)“…Oxidation of aromatic rings and its alkyl substituents are often competing initial steps of organic pollutant transformation. The use of compound-specific…”
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Isotope fractionation associated with the simultaneous biodegradation of multiple nitrophenol isomers by Pseudomonas putida B2
Published in Environmental science--processes & impacts (24-05-2017)“…Quantifying the extent of biodegradation of nitroaromatic compounds (NACs) in contaminated soils and sediments is challenging because of competing oxidative…”
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10
Using Compound-Specific Isotope Analysis to Assess Biodegradation of Nitroaromatic Explosives in the Subsurface
Published in Environmental science & technology (02-07-2013)“…Assessing the fate of nitroaromatic explosives in the subsurface is challenging because contaminants are present in different phases (e.g., bound to soil or…”
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Isotope Fractionation Associated with the Biodegradation of 2- and 4‑Nitrophenols via Monooxygenation Pathways
Published in Environmental science & technology (17-12-2013)“…Monooxygenation is an important route of nitroaromatic compound (NAC) biodegradation and it is widely found for cometabolic transformations of NACs and other…”
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12
Temperature-dependent carbon isotope fractionation in coccolithophores
Published in Frontiers in earth science (Lausanne) (04-07-2024)“…Introduction: The stable carbon isotope ratio of long-chain alkenones produced by marine haptophyte phytoplankton has often been used to estimate past…”
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13
Microbial succession and dynamics in meromictic Mono Lake, California
Published in Geobiology (01-07-2021)“…Mono Lake is a closed‐basin, hypersaline, alkaline lake located in Eastern Sierra Nevada, California, that is dominated by microbial life. This unique…”
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14
A DFT study of permanganate oxidation of toluene and its ortho-nitroderivatives
Published in Journal of molecular modeling (2014)“…Calculations of alternative oxidation pathways of toluene and its ortho -substituted nitro derivatives by permanganate anion have been performed. The…”
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15
Biosynthetic and catabolic pathways control amino acid δ 2 H values in aerobic heterotrophs
Published in Frontiers in microbiology (2024)“…The hydrogen isotope ratios (δ H values) of amino acids in all organisms are substantially fractionated relative to growth water. In addition, they exhibit…”
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16
H/¹H variation in microbial lipids is controlled by NADPH metabolism
Published in Proceedings of the National Academy of Sciences - PNAS (18-06-2019)“…The hydrogen-isotopic compositions (²H/¹H ratios) of lipids in microbial heterotrophs are known to vary enormously, by at least 40% (400‰) relative. This is…”
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17
Enzyme Kinetics of Different Types of Flavin-Dependent Monooxygenases Determine the Observable Contaminant Stable Isotope Fractionation
Published in Environmental science & technology letters (10-11-2015)“…The assessment of oxidative pollutant biotransformation by compound specific isotope analysis (CSIA) is often complicated by the variability of kinetic isotope…”
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