Search Results - "Retana, Diana"

Formin Activity and mDia1 Contribute to Maintain Axon Initial Segment Composition and Structure by Zhang, Wei, Ciorraga, María, Mendez, Pablo, Retana, Diana, Boumedine-Guignon, Norah, Achón, Beatriz, Russier, Michaël, Debanne, Dominique, Garrido, Juan José

“…The axon initial segment (AIS) is essential for maintaining neuronal polarity, modulating protein transport into the axon, and action potential generation…”
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Sprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoids by García-Domínguez, Carlota A, Martínez, Natalia, Gragera, Teresa, Pérez-Rodríguez, Andrea, Retana, Diana, León, Gonzalo, Sánchez, Agustín, Oliva, José Luis, Pérez-Sala, Dolores, Rojas, José M

“…Sprouty and Spred proteins have been widely implicated in the negative regulation of the fibroblast growth factor receptor-extracellular regulated kinase (ERK)…”
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Transcriptomic alterations in APP/PS1 mice astrocytes lead to early postnatal axon initial segment structural changes by Benitez, María José, Retana, Diana, Ordoñez-Gutiérrez, Lara, Colmena, Inés, Goméz, María José, Álvarez, Rebeca, Ciorraga, María, Dopazo, Ana, Wandosell, Francisco, Garrido, Juan José

“…Alzheimer´s disease (AD) is characterized by neuronal function loss and degeneration. The integrity of the axon initial segment (AIS) is essential to maintain…”
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Characterization of Novel Missense Variants of SERPINA1 Gene Causing Alpha-1 Antitrypsin Deficiency by Matamala, Nerea, Lara, Beatriz, Gomez-Mariano, Gema, Martínez, Selene, Retana, Diana, Fernandez, Taiomara, Silvestre, Ramona Angeles, Belmonte, Irene, Rodriguez-Frias, Francisco, Vilar, Marçal, Sáez, Raquel, Iturbe, Igor, Castillo, Silvia, Molina-Molina, María, Texido, Anna, Tirado-Conde, Gema, Lopez-Campos, Jose Luis, Posada, Manuel, Blanco, Ignacio, Janciauskiene, Sabina, Martinez-Delgado, Beatriz

“…The SERPINA1 gene is highly polymorphic, with more than 100 variants described in databases. SERPINA1 encodes the alpha-1 antitrypsin (AAT) protein, and severe…”
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A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis by Zhu, Lucía, Retana, Diana, García‐Gómez, Pedro, Álvaro‐Espinosa, Laura, Priego, Neibla, Masmudi‐Martín, Mariam, Yebra, Natalia, Miarka, Lauritz, Hernández‐Encinas, Elena, Blanco‐Aparicio, Carmen, Martínez, Sonia, Sobrino, Cecilia, Ajenjo, Nuria, Artiga, Maria‐Jesus, Ortega‐Paino, Eva, Torres‐Ruiz, Raúl, Rodríguez‐Perales, Sandra, Soffietti, Riccardo, Bertero, Luca, Cassoni, Paola, Weiss, Tobias, Muñoz, Javier, Sepúlveda, Juan Manuel, González‐León, Pedro, Jiménez‐Roldán, Luis, Moreno, Luis Miguel, Esteban, Olga, Pérez‐Núñez, Ángel, Hernández‐Laín, Aurelio, Toldos, Oscar, Ruano, Yolanda, Alcázar, Lucía, Blasco, Guillermo, Fernández‐Alén, José, Caleiras, Eduardo, Lafarga, Miguel, Megías, Diego, Graña‐Castro, Osvaldo, Nör, Carolina, Taylor, Michael D, Young, Leonie S, Varešlija, Damir, Cosgrove, Nicola, Couch, Fergus J, Cussó, Lorena, Desco, Manuel, Mouron, Silvana, Quintela‐Fandino, Miguel, Weller, Michael, Pastor, Joaquín, Valiente, Manuel, de la Lama‐Zaragoza, Adolfo, Calero‐Felix, Lourdes, Fiaño‐Valverde, Concepcion, Delgado‐López, Pedro David, Montalvo‐Afonso, Antonio, Pascual‐Llorente, Mar, Díaz‐Piqueras, Ángela, Nam‐Cha, SH, Barrena López, Cristina, Plans Ahicart, Gerard, Martínez‐Saez, Elena, Ramón y Cajal, Santiago, Nicolás, Pilar

“…We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing…”
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Abstract 3516: Metastatic colonization requires a proliferative pause linked to vascular co-option by García-Gómez, Pedro, Retana, Diana, Sanz-Martínez, Pablo, Salgado-Crespo, Irene, Hernández-Oliver, Carolina, García, Maria Isabel, Sánchez, Oliva, Troulé-Lozano, Kevin, Villar-Cerviño, Verona, Lafarga-Coscojuela, Miguel, Al-Shahrour, Fátima, Cerebral, RENACER Red Nacional de Metástasis, Valiente, Manuel

“…Abstract The physical interaction between metastasis-initiating cells and the pre-existing capillary network (a process known as vascular co-option) is…”
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TLR3 polymorphisms are associated with virologic response to hepatitis C virus (HCV) treatment in HIV/HCV coinfected patients by Jiménez-Sousa, María Angeles, Rallón, Norma, Berenguer, Juan, Pineda-Tenor, Daniel, López, Juan Carlos, Soriano, Vicente, Guzmán-Fulgencio, María, Cosín, Jaime, Retana, Diana, García-Álvarez, Mónica, Miralles, Pilar, Benito, Jose Miguel, Resino, Salvador

“…Highlights • A allele at rs3775291 was associated with decreased odds of response to therapy. • Carriers of rs13126816 A allele infected with GT2/3 had lower…”
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42. IDENTIFICATION OF BRAIN METASTASIS VULNERABILITIES USING METPLATFORM by Zhu, Lucía, Yebra, Natalia, Retana, Diana, Blanco-Aparicio, Carmen, Martínez, Sonia, Soffietti, Riccardo, Bertero, Luca, Cassoni, Paola, Weiss, Tobias, Muñoz, Javier, Manuel Sepúlveda, Juan, Pérez-Núñez, Ángel, Hernández-Laín, Aurelio, Toldos, Óscar, Caleiras, Eduardo, Nör, Carolina, Taylor, Michael D, Weller, Michael, Pastor, Joaquín, Valiente, Manuel

“…Abstract The diagnosis of brain metastasis involves high morbidity and mortality and remains an unmet clinical need in spite of being the most common tumor in…”
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