Search Results - "Retamal, Ignacio"
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1
Generalizable Protein Biosensors Based on Synthetic Switch Modules
Published in Journal of the American Chemical Society (22-05-2019)“…Allosteric protein switches are key controllers of information and energy processing in living organisms and are desirable engineered control tools in…”
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2
Periodontitis and Gestational Diabetes Mellitus: A Potential Inflammatory Vicious Cycle
Published in International journal of molecular sciences (31-10-2021)“…Periodontitis is a chronic inflammatory immune disease associated with a dysbiotic state, influenced by keystone bacterial species responsible for disrupting…”
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Porphyromonas gingivalis , a bridge between oral health and immune evasion in gastric cancer
Published in Frontiers in oncology (14-05-2024)“…( ) is a gram-negative oral pathogen associated with chronic periodontitis. Previous studies have linked poor oral health and periodontitis with oral cancer…”
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4
Differentially Expressed Genes and Signaling Pathways Potentially Involved in Primary Resistance to Chemo-Immunotherapy in Advanced-Stage Gastric Cancer Patients
Published in International journal of molecular sciences (20-12-2022)“…Recently, the combination of chemotherapy plus nivolumab (chemo-immunotherapy) has become the standard of care for advanced-stage gastric cancer (GC) patients…”
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A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer
Published in BMC cancer (16-09-2021)“…Background Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical…”
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6
Exploring the structural acrobatics of fold-switching proteins using simplified structure-based models
Published in Biophysical reviews (01-08-2023)“…Metamorphic proteins are a paradigm of the protein folding process, by encoding two or more native states, highly dissimilar in terms of their secondary,…”
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Relationship between soluble neuropilin-1 in the gingival crevicular fluid of early pregnant women and different severities of periodontitis: A cross-sectional study
Published in Journal of oral biology and craniofacial research (Amsterdam) (01-03-2023)“…Pregnancy exacerbates the periodontal inflammation; however, the biological mediators involved are not well characterized. Neuropilins (NRPs) are transmembrane…”
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Glycated Collagen Stimulates Differentiation of Gingival Myofibroblasts
Published in Journal of periodontology (1970) (01-09-2017)“…Background: Glucose‐derived metabolites may alter the structure and biologic properties of important proteins in periodontium, such as collagens. As a…”
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Transcriptome analysis reveals regulatory networks underlying differential susceptibility to Botrytis cinerea in response to nitrogen availability in Solanum lycopersicum
Published in Frontiers in plant science (04-11-2015)“…Nitrogen (N) is one of the main limiting nutrients for plant growth and crop yield. It is well documented that changes in nitrate availability, the main N…”
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Chilean Gastric Cancer Task Force: A study protocol to obtain a clinical and molecular classification of a cohort of gastric cancer patients
Published in Medicine (Baltimore) (01-04-2018)“…Gastric cancer (GC) is the world's second-leading cause of neoplastic mortality. Genetic alterations, response to treatments, and mortality rates are highly…”
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A Molecular Stratification of Chilean Gastric Cancer Patients with Potential Clinical Applicability
Published in Cancers (10-07-2020)“…Gastric cancer (GC) is a complex and heterogeneous disease. In recent decades, The Cancer Genome Atlas (TCGA) and the Asian Cancer Research Group (ACRG)…”
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12
Osteonecrosis of the jaws
Published in Revista medíca de Chile (01-07-2020)“…Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the…”
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High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study
Published in Cancers (30-08-2019)“…Gastric cancer (GC) is a heterogeneous disease. This heterogeneity applies not only to morphological and phenotypic features but also to geographical…”
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Soluble neuropilin-1 in gingival crevicular fluid is associated with rheumatoid arthritis: An exploratory case-control study
Published in Journal of oral biology and craniofacial research (Amsterdam) (01-04-2021)“…To explore the soluble Neuropilin-1 (sNRP-1) concentrations in gingival crevicular fluid (GCF) and the periodontal clinical status of patients with Rheumatoid…”
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15
Chilean Registry for Neuroendocrine Tumors: A Latin American Perspective
Published in Hormones & cancer (01-02-2019)“…Neuroendocrine tumors (NETs) are relatively rare and highly heterogeneous neoplasms. Despite this, recent studies from North America and Central Europe have…”
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Retrospective Analysis of Chilean and Mexican GI Stromal Tumor Registries: A Tale of Two Latin American Realities
Published in JCO global oncology (01-04-2020)“…Like other malignancies, GI stromal tumors (GIST) are highly heterogeneous. This not only applies to histologic features and malignant potential, but also to…”
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Dimer dissociation is a key energetic event in the fold-switch pathway of KaiB
Published in Biophysical journal (15-03-2022)“…Cyanobacteria possesses the simplest circadian clock, composed of three proteins that act as a phosphorylation oscillator: KaiA, KaiB, and KaiC. The timing of…”
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Angiogenesis inhibitors in early development for gastric cancer
Published in Expert opinion on investigational drugs (02-09-2017)“…Angiogenesis, or the generation of new blood vessels from pre-existent ones is a critical process for tumor growth and progression. Hence, the development of…”
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Health literacy and adherence to treatment in different districts in Chile
Published in Health promotion international (30-08-2021)“…Summary The relationship between health literacy and adherence has been described in medical literature, especially for patients with non-communicable diseases…”
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The Mechanistic Link Between Oral Health and Immune Profile in Gastric Cancer
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-11-2023)Get full text
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