Comprehensive Review of Emergence and Virology of Tickborne Bourbon Virus in the United States

The emergence of SARS-CoV-2 and the worldwide COVID-19 pandemic triggered considerable attention to the emergence and evolution of novel human pathogens. Bourbon virus (BRBV) was first discovered in 2014 in Bourbon County, Kansas, USA. Since its initial discovery, several cases of BRBV infection in...

Full description

Saved in:

Bibliographic Details
Published in:	Emerging infectious diseases Vol. 29; no. 1; pp. 1 - 7
Main Authors:	Roe, Molly K, Huffman, Elise R, Batista, Yara S, Papadeas, George G, Kastelitz, Sydney R, Restivo, Anna M, Stobart, Christopher C
Format:	Journal Article
Language:	English
Published:	United States U.S. National Center for Infectious Diseases 01-01-2023 Centers for Disease Control and Prevention
Subjects:	Arachnids Bourbon virus Cell culture Cell Line CME Comprehensive Review of Emergence and Virology of Tickborne Bourbon Virus in the United States COVID-19 Disease Disease transmission Distribution Emerging communicable diseases emerging virus Epidemics Evolutionary biology Gene expression Genomes Health aspects Humans Identification and classification Infection Infections Influenza, Human Kansas Medical research Medicine, Experimental Microscopy Missouri Pandemics Pathogens Phylogenetics Proteins Public health Risk factors RNA RNA polymerase RNA viruses Thogotovirus Thrombocytopenia Tick-borne diseases tickborne viruses United States United States - epidemiology vector-borne infections Virology Viruses United States Missouri Kansas United States > US RNA viruses Bourbon virus viruses vector-borne infections tickborne viruses United States thogotovirus emerging virus zoonoses
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The emergence of SARS-CoV-2 and the worldwide COVID-19 pandemic triggered considerable attention to the emergence and evolution of novel human pathogens. Bourbon virus (BRBV) was first discovered in 2014 in Bourbon County, Kansas, USA. Since its initial discovery, several cases of BRBV infection in humans have been identified in Kansas, Oklahoma, and Missouri. BRBV is classified within the Thogotovirus genus; these negative-strand RNA viruses appear to be transmitted by ticks, and much of their biology remains unknown. In this review, we describe the emergence, virology, geographic range and ecology, and human disease caused by BRBV and discuss potential treatments for active BRBV infections. This virus and other emerging viral pathogens remain key public health concerns and require continued surveillance and study to mitigate human exposure and disease.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2901.212295