Search Results - "Resta, T C"

NFATc3 is required for chronic hypoxia-induced pulmonary hypertension in adult and neonatal mice by Bierer, R, Nitta, C H, Friedman, J, Codianni, S, de Frutos, S, Dominguez-Bautista, J A, Howard, T A, Resta, T C, Bosc, L V Gonzalez

“…Pulmonary hypertension occurs with prolonged exposure to chronic hypoxia in both adults and neonates. The Ca(2+)-dependent transcription factor, nuclear factor…”
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Selective upregulation of arterial endothelial nitric oxide synthase in pulmonary hypertension by Resta, T C, Gonzales, R J, Dail, W G, Sanders, T C, Walker, B R

“…We have previously demonstrated that arterial, but not venous, vasodilatory responses to endothelium-derived nitric oxide (EDNO)-dependent agonists are…”
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Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation by Resta, T C, Walker, B R

“…We have previously demonstrated that chronic hypoxia (CH) augments pulmonary arterial dilation to the endothelium-derived nitric oxide (EDNO)-dependent…”
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Orally administered L-arginine does not alter right ventricular hypertrophy in chronically hypoxic rats by Resta, T C, Walker, B R

“…Evidence suggests that nitric oxide synthesis within the pulmonary circulation may be attenuated during chronic hypoxia in Wistar rats due to reduced…”
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Pulmonary vasodilatory response to neurohypophyseal peptides in the rat by Russ, R D, Resta, T C, Walker, B R

“…Experiments were performed on isolated salt-perfused rat lungs to determine the receptor type(s) responsible for the pulmonary vascular effects of the…”
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Role of endogenous opioids and serotonin in the hemodynamic response to hemorrhage during hypoxia by Resta, T C, Resta, J M, Walker, B R

“…Previous studies from our laboratory indicate that acute but not chronic hypoxia decreases the hemorrhage volume required to elicit reflex hypotension…”
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Cardiovascular responses to hemorrhage during acute and chronic hypoxia by Resta, T C, Russ, R D, Doyle, M P, Martinez, J M, Walker, B R

“…Previous work from our laboratory had demonstrated attenuation of systemic vasoreactivity to pressor agents in rats after acute or chronic exposure to hypoxia…”
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Enhanced Renal Vasoconstrictor Responsiveness to Vasopressin After Renal Denervation by Resta, Thomas C, Walker, Benjimen R

“…Previous studies from our laboratory and others demonstrated a relative insensitivity of the renal vasculature to the vasoconstrictor influences of arginine…”
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Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression by Resta, T C, Kanagy, N L, Walker, B R

“…Female rats develop less severe pulmonary hypertension (PH) in response to chronic hypoxia compared with males, thus implicating a potential role for ovarian…”
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Glibenclamide does not reverse attenuated vasoreactivity to acute or chronic hypoxia by Eichinger, M R, Resta, T C, Balderrama, D S, Herrera, G M, Richardson, L A, Resta, J M, Walker, B R

“…Recent studies from our laboratory have shown that acute and chronic hypoxic exposures are associated with attenuated systemic vasoreactivity in conscious…”
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Maintained Vasodilatory Response to Cromakalim After Inhibition of Nitric Oxide Synthesis by Herrera, Gerald M, Resta, Thomas C, Candelaria, John J, Walker, Benjimen R

“…Activation of vascular smooth-muscle adenosine triphosphate-sensitive potassium channels (KATP channels) causes membrane hyperpolarization, reduced entry of Ca…”
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Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia by Caudill, T K, Resta, T C, Kanagy, N L, Walker, B R

“…Chronic hypoxic exposure has been previously demonstrated to attenuate systemic vasoconstrictor activity to a variety of agents. This attenuated responsiveness…”
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Nitric oxide-dependent pulmonary vasodilation in polycythemic rats by Walker, B R, Resta, T C, Nelin, L D

“…Polycythemia causes increased vascular production of nitric oxide (NO), most likely secondary to an effect of elevated vascular shear stress to enhance…”
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A67 BREAKDOWN: THE CELLULAR CONTRIBUTION TO PULMONARY HYPERTENSION: Enhanced Endothelium-Dependent Pulmonary Vasodilation And Enos Expression Limit Increased Vasoconstrictor Sensitivity In Neonatal Chronic Hypoxia by Sheak, J R, DeKay, R J, Jernigan, N L, Walker, B R, Resta, T C

“…To test this hypothesis, we assessed effects of the NO synthase (NOS) inhibitor Nw-nitro-L-arginine (L-NNA) on baseline pulmonary vascular resistance (PVR) and…”
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PULMONARY CIRCULATION DEMONSTRATION USING AN ISOLATED RAT LUNG MODEL by Resta, Thomas C, Eichinger, Mark R, Russ, Roy D, Walker, Benjimen R

“…We have developed a pulmonary circulation laboratory exercise that effectively illustrates basic concepts typically taught in a graduate physiology curriculum…”
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Unaltered vasoconstrictor responsiveness after iNOS inhibition in lungs from chronically hypoxic rats by Resta, T C, O'Donaughy, T L, Earley, S, Chicoine, L G, Walker, B R

“…Previous studies suggest that inducible (i) nitric oxide synthase (NOS) expression within the pulmonary vasculature is increased in rats with chronic hypoxia…”
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B27 HYPOXIA AND THE PULMONARY VASCULATURE: BREATHLESS IN SAN FRANCISCO: T Helper 17 Cells Contribute To Chronic Hypoxia-Induced Pulmonary Hypertension by Maston, L D, Jones, D T, Cannon, J L, Wang, W, Wei, Y, Xuan, W, Resta, T C, Bosc, L Gonzalez

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Reactive oxygen species and RhoA signaling in vascular smooth muscle: role in chronic hypoxia-induced pulmonary hypertension by Resta, Thomas C, Broughton, Brad R S, Jernigan, Nikki L

“…Increases in myofilament Ca2+ sensitivity resulting from stimulation of RhoA and Rho kinase represent a primary mechanism of vasoconstriction and associated…”
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Segmental vasodilatory effectiveness of inhaled NO in lungs from chronically hypoxic rats by Resta, ThomasC, Sanders, ThomasC, Eichinger, MarkR, Crowley, MarkR, Walker, BenjimenR

“…Inhaled nitric oxide (iNO) is being used to treat pulmonary hypertension in a variety of chronic lung diseases associated with pulmonary vascular remodeling…”
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Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia by Resta, T C, Chicoine, L G, Omdahl, J L, Walker, B R

“…We previously demonstrated augmented endothelium-derived nitric oxide (EDNO)-dependent pulmonary arterial dilation and increased arterial endothelial nitric…”
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