Search Results - "Ressler, Valerie T"

Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor by Thomas, Sydney P, Hoang, Trish T, Ressler, Valerie T, Raines, Ronald T

“…Angiogenin (ANG) is a secretory ribonuclease that promotes the proliferation of endothelial cells, leading to angiogenesis. This function relies on its…”
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Development of a rapid, simple, and sensitive point-of-care technology platform utilizing ternary NanoLuc by Torio, Emily A., Ressler, Valerie T., Kincaid, Virginia A., Hurst, Robin, Hall, Mary P., Encell, Lance P., Zimmerman, Kristopher, Forsyth, Stuart K., Rehrauer, William M., Accola, Molly A., Hsu, Chia-Chang, Machleidt, Thomas, Dart, Melanie L.

“…Point-of-care tests are highly valuable in providing fast results for medical decisions for greater flexibility in patient care. Many diagnostic tests, such as…”
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Consequences of the Endogenous N‑Glycosylation of Human Ribonuclease 1 by Ressler, Valerie T, Raines, Ronald T

“…Ribonuclease 1 (RNase 1) is the most prevalent human homologue of the archetypal enzyme RNase A. RNase 1 contains sequons for N-linked glycosylation at Asn34,…”
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Esterification Delivers a Functional Enzyme into a Human Cell by Ressler, Valerie T, Mix, Kalie A, Raines, Ronald T

“…A major hurdle in chemical biology is the delivery of native proteins into the cytosol of mammalian cells. Herein, we report that esterification of the…”
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Structure and Dynamics of N‑Glycosylated Human Ribonuclease 1 by Kilgore, Henry R, Latham, Andrew P, Ressler, Valerie T, Zhang, Bin, Raines, Ronald T

“…Glycosylation is a common modification that can endow proteins with altered physical and biological properties. Ribonuclease 1 (RNase 1), which is the human…”
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Toward a Point-of-Need Bioluminescence-Based Immunoassay Utilizing a Complete Shelf-Stable Reagent by Hall, Mary P, Kincaid, Virginia A, Jost, Emily A, Smith, Thomas P, Hurst, Robin, Forsyth, Stuart K, Fitzgerald, Connor, Ressler, Valerie T, Zimmermann, Kris, Lazar, Dan, Wood, Monika G, Wood, Keith V, Kirkland, Thomas A, Encell, Lance P, Machleidt, Thomas, Dart, Melanie L

“…Enzyme-linked immunosorbent assays (ELISAs) are used extensively for the detection and quantification of biomolecules in clinical diagnostics as well as in…”
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Simple, Rapid Chemical Labeling and Screening of Antibodies with Luminescent Peptides by Kincaid, Virginia A., Wang, Hui, Sondgeroth, Casey A., Torio, Emily A., Ressler, Valerie T., Fitzgerald, Connor, Hall, Mary P., Hurst, Robin, Wood, Monika G., Gilden, Julia K., Kirkland, Thomas A., Lazar, Dan, Chia-Chang, Hsu, Encell, Lance P., Machleidt, Thomas, Zhou, Wenhui, Dart, Melanie L.

“…Sensitive and selective detection assays are essential for the accurate measurement of analytes in both clinical and research laboratories. Immunoassays that…”
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Monofunctionalization with dextrans endows cell‐penetrative properties to proteins by Kilgore, Henry Ralph, Ressler, Valerie T, Raines, Ronald T

“…Dextrans have proven to be a widely useful class of polysaccharides, with applications ranging from antithrombotic agents to enhancers of vaccine stability. We…”
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