Search Results - "Resende, Isabela"
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Human leptospirosis: In search for a better vaccine
Published in Scandinavian journal of immunology (01-11-2023)“…Leptospirosis is a neglected disease caused by bacteria of the genus Leptospira and is more prevalent in tropical and subtropical countries. This pathogen…”
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Occurrence of human visceral leishmaniasis in the Central-West region of Brazil: A systematic review
Published in Acta tropica (01-01-2023)“…•Visceral Leishmaniasis is urbanizing in Brazil in recent decades;•This systematic review shows factors associated with Visceral Leishmaniasis;•In Central-West…”
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Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue
Published in PloS one (05-01-2021)“…Memory impairment has been associated with chronic Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. In…”
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Maternal care and child physical health: Impact of the exposure to adverse experiences during the first year of life of vulnerable children
Published in Child : care, health & development (01-05-2022)“…Introduction Adverse childhood experiences (ACEs) can negatively affect children's current and future health. Objectives This study aims to analyse the impact…”
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CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi -Induced Chronic Cardiomyopathy
Published in Frontiers in immunology (03-03-2020)“…CCL3, a member of the CC-chemokine family, has been associated with macrophage recruitment to heart tissue and parasite control in the acute infection of mouse…”
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Prevalence and epidemiological aspects of Chikungunya fever in states of the Northeast region of Brazil: A systematic review
Published in Acta tropica (01-05-2023)“…•Chikungunya fever is caused by the chikungunya virus, which is common in urban areas;.•This systematic review analyzes factors associated with chikungunya…”
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Clinical-epidemiological aspects and prognostic factors associated with death from visceral leishmaniasis between the years 2010 to 2019 in the Central-West region of Brazil
Published in Parasitology international (01-02-2024)“…In Brazil, the fatality rate for visceral leishmaniasis is high, and it is important to investigate its associated factors. The aim of this study was to…”
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Association of maternal depression, family composition and poverty with maternal care and physical health of children in the first year of life
Published in Revista brasileira de crescimento e desenvolvimento humano (31-03-2021)“…Objetivo: Analisar como depressão materno, composição da família e condições socioeconômicas afetam a saúde física de crianças no primeiro ano de vida…”
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A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy
Published in PLoS pathogens (01-01-2015)“…Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical neglected tropical disease. Specific immunity promotes acute phase survival…”
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MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes
Published in PLoS neglected tropical diseases (18-06-2015)“…Chagas disease is caused by the parasite Trypanosoma cruzi, and it begins with a short acute phase characterized by high parasitemia followed by a life-long…”
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Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection
Published in Scientific reports (21-12-2017)“…Chagas disease, caused by the parasite Trypanosoma cruzi , is endemic in Latin America. Its acute phase is associated with high parasitism, myocarditis and…”
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CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy
Published in PLoS pathogens (01-04-2012)“…In Chagas disease, CD8(+) T-cells are critical for the control of Trypanosoma cruzi during acute infection. Conversely, CD8(+) T-cell accumulation in the…”
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Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy
Published in PLoS neglected tropical diseases (01-03-2023)“…Chronic Chagas cardiomyopathy (CCC) is one of the leading causes of morbidity and mortality due to cardiovascular disorders in endemic areas of Chagas disease…”
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Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease
Published in Memórias do Instituto Oswaldo Cruz (01-06-2014)“…Heart tissue inflammation, progressive fibrosis and electrocardiographic alterations occur in approximately 30% of patients infected by Trypanosoma cruzi,…”
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Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy
Published in Frontiers in cellular and infection microbiology (14-07-2021)“…Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe form of Chagas disease, a neglected tropical illness caused by the protozoan Trypanosoma…”
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Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu
Published in Journal of neuroinflammation (06-09-2017)“…In conditions of immunosuppression, the central nervous sty 5ystem (CNS) is the main target tissue for the reactivation of infection by Trypanosoma cruzi, the…”
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Pentoxifylline reverses chronic experimental Chagasic cardiomyopathy in association with repositioning of abnormal CD8+ T-cell response
Published in PLoS neglected tropical diseases (01-03-2015)“…Chronic chagasic cardiomyopathy (CCC), the main clinical sign of Chagas disease, is associated with systemic CD8+ T-cell abnormalities and CD8-enriched…”
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An experimental analysis of coffee beans dynamics in a rotary drum
Published in Canadian journal of chemical engineering (01-12-2017)“…Brazil is the largest producer and exporter of coffee in the world, one of the main global commodities. During the processing of coffee beans, rotary drums are…”
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Pro-Inflammatory Profile of Children Exposed to Maternal Chikungunya Virus Infection during the Intrauterine Period: A One-Year Follow-Up Study
Published in Viruses (26-08-2022)“…Chikungunya virus (CHIKV) vertical transmission occurs due to maternal viremia in the prepartum. Clinical presentation in neonates can be varied; however, the…”
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Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas' Heart Disease
Published in Mediators of Inflammation (01-01-2014)“…Background. Chagas disease (CD) is characterized by parasite persistence and immunological unbalance favoring systemic inflammatory profile. Chronic chagasic…”
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