Search Results - "Resende, Diana I. S. P."
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Evaluation of the Cytotoxic and Antiviral Effects of Small Molecules Selected by In Silico Studies as Inhibitors of SARS-CoV-2 Cell Entry
Published in Molecules (Basel, Switzerland) (01-10-2023)“…The spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relies on host cell surface glycans to facilitate interaction with the…”
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2
Antibacterial Potential of Symmetrical Twin-Drug 3,6-Diaminoxanthones
Published in Pharmaceuticals (Basel, Switzerland) (01-02-2024)“…Global health faces a significant issue with the rise of infectious diseases caused by bacteria, fungi, viruses, and parasites. The increasing number of…”
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Effect of Indole-Containing Pyrazino[2,1- b ]quinazoline-3,6-diones in the Virulence of Resistant Bacteria
Published in Antibiotics (Basel) (17-05-2023)“…Drug resistance is rising to alarming levels, constituting one of the major threats to global health. The overexpression of efflux pumps and the formation of…”
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4
Natural and Synthetic Xanthone Derivatives Counteract Oxidative Stress via Nrf2 Modulation in Inflamed Human Macrophages
Published in International journal of molecular sciences (01-11-2022)“…Natural products have attracted attention due to their safety and potential effectiveness as anti-inflammatory drugs. Particularly, xanthones owning a unique 9…”
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5
Antithrombotics from the Sea: Polysaccharides and Beyond
Published in Marine drugs (16-03-2019)“…Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural…”
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Synthesis of a Small Library of Nature-Inspired Xanthones and Study of Their Antimicrobial Activity
Published in Molecules (Basel, Switzerland) (21-05-2020)“…A series of thirteen xanthones - was prepared based on substitutional (appendage) diversity reactions. The series was structurally characterized based on their…”
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Marine Ingredients for Sensitive Skin: Market Overview
Published in Marine drugs (17-08-2021)“…Marine ingredients are a source of new chemical entities with biological action, which is the reason why they have gained relevance in the cosmetic industry…”
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From Natural Xanthones to Synthetic C-1 Aminated 3,4-Dioxygenated Xanthones as Optimized Antifouling Agents
Published in Marine drugs (13-11-2021)“…Biofouling, which occurs when certain marine species attach and accumulate in artificial submerged structures, represents a serious economic and environmental…”
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Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products
Published in Marine drugs (31-07-2018)“…Many fungal quinazolinone metabolites, which contain the methyl-indole pyrazino [1,2- ]quinazoline-3,6-dione core, have been found to possess promising…”
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10
Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects
Published in Molecules (Basel, Switzerland) (01-02-2019)“…New quinazolinone derivatives of the marine-derived alkaloids fiscalin B ( ) and fumiquinazoline G ( ), with neuroprotective and antitumor effects, were…”
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11
Up-to-Date Overview of the Use of Natural Ingredients in Sunscreens
Published in Pharmaceuticals (Basel, Switzerland) (18-03-2022)“…The photoprotective skincare segment is in high demand to meet consumer concerns on UV-induced skin damage, with a recent trend towards sunscreen alternatives…”
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12
Xanthones Active against Multidrug Resistance and Virulence Mechanisms of Bacteria
Published in Antibiotics (Basel) (19-05-2021)“…The emergence of multidrug and extensively drug-resistant pathogenic bacteria able to resist to the action of a wide range of antibiotics is becoming a growing…”
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13
New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles
Published in RSC advances (21-08-2020)“…Due to the emergence of multidrug-resistant pathogenic microorganisms, the search for novel antimicrobials is urgent. Inspired by marine alkaloids, a series of…”
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14
Determination of the Absolute Configuration of Bioactive Indole-Containing Pyrazino[2,1- b ]quinazoline-3,6-diones and Study of Their In Vitro Metabolic Profile
Published in Molecules (Basel, Switzerland) (21-08-2021)“…In recent decades, fungi-derived naturally occurring quinazolines have emerged as potential drug candidates. Nevertheless, most studies are conducted for…”
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Efficacy, Stability, and Safety Evaluation of New Polyphenolic Xanthones Towards Identification of Bioactive Compounds to Fight Skin Photoaging
Published in Molecules (Basel, Switzerland) (16-06-2020)“…Antioxidants have long been used in the cosmetic industry to prevent skin photoaging, which is mediated by oxidative stress, making the search for new…”
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From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones
Published in Molecules (Basel, Switzerland) (15-01-2021)“…This work reviews the contributions of the corresponding author (M.M.M.P.) and her research group to Medicinal Chemistry concerning the isolation from plant…”
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17
Lichen Xanthones as Models for New Antifungal Agents
Published in Molecules (Basel, Switzerland) (12-10-2018)“…Due to the emergence of multidrug-resistant pathogenic microorganisms, the search for new antimicrobial compounds plays an important role in current medicinal…”
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18
Usage of Synthetic Peptides in Cosmetics for Sensitive Skin
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2021)“…Sensitive skin is characterized by symptoms of discomfort when exposed to environmental factors. Peptides are used in cosmetics for sensitive skin and stand…”
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A Practical Toolkit for the Detection, Isolation, Quantification, and Characterization of Siderophores and Metallophores in Microorganisms
Published in ACS omega (25-06-2024)“…Siderophores are well-recognized low-molecular-weight compounds produced by numerous microorganisms to acquire iron from the surrounding environments. These…”
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Skin Depigmenting Agents in Anti-Aging Cosmetics: A Medicinal Perspective on Emerging Ingredients
Published in Applied sciences (01-01-2022)“…Human skin aging results from intrinsic and extrinsic factors. Uneven pigmentation is one of the major changes of extrinsic aging. Many compounds have been…”
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