Search Results - "Resar, Linda Ms"

HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis by Schuldenfrei, Andrew, Belton, Amy, Kowalski, Jeanne, Talbot, Jr, C Conover, Di Cello, Francescopaolo, Poh, Weijie, Tsai, Hua-Ling, Shah, Sandeep N, Huso, Tait H, Huso, David L, Resar, Linda M S

“…Although the high mobility group A1 (HMGA1) gene is widely overexpressed in diverse cancers and portends a poor prognosis in some tumors, the molecular…”
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Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation by DHAR, Arindam, JING HU, REEVES, Raymond, RESAR, Linda M. S, COLBURN, Nancy H

“…Activation of the transcription factor AP-1 (activator protein-1) is required for tumor promotion and maintenance of malignant phenotype. A number of…”
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Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures by Chou, Bin-Kuan, Mali, Prashant, Huang, Xiaosong, Ye, Zhaohui, Dowey, Sarah N, Resar, Linda MS, Zou, Chunlin, Zhang, Y Alex, Tong, Jay, Cheng, Linzhao

“…To identify accessible and permissive human cell types for efficient derivation of induced pluripotent stem cells （iPSCs）, we investigated epigenetic and gene…”
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Use of pegylated interferon in young patients with polycythemia vera and essential thrombocythemia by Kucine, Nicole, Bergmann, Shayla, Krichevsky, Spencer, Jones, Devin, Rytting, Michael, Jain, Juhi, Bennett, Carolyn M., Resar, Linda M.S., Mascarenhas, John, Verstovsek, Srdan, Hoffman, Ronald

“…Myeloproliferative neoplasms (MPN) are rare disorders in young patients, and because of this, standardized treatment recommendations are not available…”
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Doubling up on function: dual-specificity tyrosine-regulated kinase 1A (DYRK1A) in B cell acute lymphoblastic leukemia by Kim, Jung-Hyun, Li, Liping, Resar, Linda Ms

“…DYRK1A, the dual-specificity kinase, is again doubling up on function, as reported by Bhansali, Rammohan, and colleagues in this issue of the JCI. DYRK1A is an…”
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Taking the STING out of acute myeloid leukemia through macrophage-mediated phagocytosis by Dalton, William Brian, Ghiaur, Gabriel, Resar, Linda Ms

“…Macrophages within the bone marrow (BM) microenvironment take on unexpected roles in acute myeloid leukemia (AML) as reported by Moore and colleagues in this…”
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Getting into good trouble: Black lives matter and Black professors matter by Chisholm, Briyana, Neptune, Enid R, Golden, Sherita Hill, Resar, Linda Ms

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A novel method of data analysis for utilization of red blood cell transfusion by Frank, Steven M., Resar, Linda M.S., Rothschild, James A., Dackiw, Elizabeth A., Savage, Will J., Ness, Paul M.

“…Background A necessary component of an effective blood management program is the accurate and comprehensive collection and analysis of blood utilization data…”
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Abstract 1704: High mobility group A1 chromatin remodeling protein expands the intestinal stem cell compartment and Paneth cell niche through Wnt-catenin signaling and Sox9 by Xian, Lingling, Huso, Tait, Belton, Amy, Huso, David, Resar., Linda MS

“…The High Mobility Group A1 (HMGA1) gene is overexpressed in most poorly differentiated cancers and high levels portend adverse clinical outcomes, although the…”
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Efficacy of education followed by computerized provider order entry with clinician decision support to reduce red blood cell utilization by Zuckerberg, Gabriel S., Scott, Andrew V., Wasey, Jack O., Wick, Elizabeth C., Pawlik, Timothy M., Ness, Paul M., Patel, Nishant D., Resar, Linda M.S., Frank, Steven M.

“…BACKGROUND Two necessary components of a patient blood management program are education regarding evidence‐based transfusion guidelines and computerized…”
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Bloodless medicine: current strategies and emerging treatment paradigms by Resar, Linda M.S., Wick, Elizabeth C., Almasri, Talal Nael, Dackiw, Elizabeth A., Ness, Paul M., Frank, Steven M.

“…BACKGROUND Advances in our understanding of the risks associated with allogeneic blood transfusions (ABTs) and the growing number of patients who wish to avoid…”
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Characterizing metabolic changes in human colorectal cancer by Williams, Michael D., Zhang, Xing, Park, Jeong-Jin, Siems, William F., Gang, David R., Resar, Linda M. S., Reeves, Raymond, Hill, Herbert H.

“…Colorectal cancer (CRC) remains a leading cause of cancer death worldwide, despite the fact that it is a curable disease when diagnosed early. The development…”
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Equity and diversity in academic medicine: a perspective from the JCI editors by Resar, Linda Ms, Jaffee, Elizabeth M, Armanios, Mary, Jackson, Sarah, Azad, Nilofer S, Horton, Maureen R, Kaplan, Mariana J, Laiho, Marikki, Maus, Marcela V, Sumner, Charlotte J, Wheelan, Sarah J, Wills-Karp, Marsha

“…The #MeToo movement has taken on sexual harassment in the workplace and served to inform the world that these unacceptable and illegal acts have become…”
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The high mobility group A1 molecular switch: turning on cancer - can we turn it off? by Huso, Tait H, Resar, Linda M S

“…Emerging evidence demonstrates that the high mobility group A1 (HMGA1) chromatin remodeling protein is a key molecular switch required by cancer cells for…”
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HMGA2 Participates in Transformation in Human Lung Cancer by Di Cello, Francescopaolo, Hillion, Joelle, Hristov, Alexandra, Wood, Lisa J, Mukherjee, Mita, Schuldenfrei, Andrew, Kowalski, Jeanne, Bhattacharya, Raka, Ashfaq, Raheela, Resar, Linda M S

“…Although previous studies have established a prominent role for HMGA1 (formerly HMG-I/Y ) in aggressive human cancers, the role of HMGA2 (formerly HMGI-C ) in…”
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Ultramassive transfusion: give blood, save a life by Frank, Steven M., Johnson, Daniel J., Resar, Linda M.S.

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HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma by Hristov, Alexandra C, Cope, Leslie, Di Cello, Francescopaolo, Reyes, Marcelo Delos, Singh, Mansher, Hillion, Joelle A, Belton, Amy, Joseph, Biju, Schuldenfrei, Andrew, Iacobuzio-Donahue, Christine A, Maitra, Anirban, Resar, Linda MS

“…Although pancreatic ductal adenocarcinoma is a common and almost uniformly fatal cancer, little is known about the molecular events that lead to tumor…”
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Hitting the bull’s eye: targeting HMGA1 in cancer stem cells by Yanagisawa, Breann L, Resar, Linda MS

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IBRUTinib: BRUTe force against bortezomib-resistant myeloma cells by Xian, Lingling, Huff, Carol Ann, Resar, Linda MS

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AKNA： Another AT-hook transcription factor ＂hooking-up＂ with inflammation by Moliterno, Alison R, Resar, Linda MS

“…Previous studies highlight a key role for AT-hook transcription factors as master regulators of fundamental cellu- lar processes involved in development,…”
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