Search Results - "Requena Ibáñez, Juan Antonio"
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Cardioprotective Effect of Empagliflozin and Circulating Ketone Bodies During Acute Myocardial Infarction
Published in Circulation. Cardiovascular imaging (01-04-2023)“…SGLT2i (sodium-glucose cotransporter-2 inhibitors) improve clinical outcomes in patients with heart failure, but the mechanisms of action are not completely…”
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Empagliflozin improves quality of life in nondiabetic HFrEF patients. Sub-analysis of the EMPATROPISM trial
Published in Diabetes & metabolic syndrome clinical research & reviews (01-02-2022)“…Initially considered as just anti-diabetic agents, SGLT2-i show remarkable cardiac and renal benefits independently of its hypoglycemic activity. We used the…”
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Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics
Published in Journal of the American College of Cardiology (23-04-2019)“…Empagliflozin cardiac benefits in the EMPA-REG OUTCOME (Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients) trial cannot be…”
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Mechanistic Insights of Empagliflozin in Nondiabetic Patients With HFrEF: From the EMPA-TROPISM Study
Published in JACC. Heart failure (01-08-2021)“…OBJECTIVESThe goal of this study was to evaluate the effect of empagliflozin, in addition to optimal medical treatment, on epicardial adipose tissue (EAT),…”
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Rationale and Design of the SOTA-P-CARDIA Trial (ATRU-V): Sotagliflozin in HFpEF Patients Without Diabetes
Published in Cardiovascular drugs and therapy (15-06-2023)“…Heart failure with preserved ejection fraction (HFpEF) is now the most common form of heart failure (HF). This syndrome is associated with an elevated…”
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Per-Protocol Versus Intention-to-Treat in Clinical Trials: The Example of GLOBAL-LEADERS Trial
Published in Journal of the American Heart Association (17-05-2022)Get full text
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Patent foramen ovale and anticardiolipin antibodies, a strange cause of bilateral kidney infarcion
Published in Nefrología (01-01-2018)Get full text
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Prolyl Hydroxylase Inhibitors: a New Opportunity in Renal and Myocardial Protection
Published in Cardiovascular drugs and therapy (01-12-2022)“…Hypoxia, via the activity of hypoxia-inducible factors (HIFs), plays a crucial role in fibrosis, inflammation, and oxidative injury, processes which are…”
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Not only how much, but also how to, when measuring epicardial adipose tissue
Published in Magnetic resonance imaging (01-02-2022)“…Epicardial Adipose Tissue (EAT) is drawing increasing attention. As a quantifiable, modifiable, and potentially new cardiovascular therapeutic target, its…”
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Dual SGLT1 and SGLT2 inhibition: more than the sum of its parts
Published in Revista española de cardiología (English ed.) (01-07-2024)Get full text
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Foramen oval permeable con anticardiolipina+, una causa rara de infartos renales múltiples
Published in Nefrología (01-01-2018)Get full text
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SGLT2i in heart failure: can their benefits be expanded across the entire spectrum of ejection fraction?
Published in Revista española de cardiología (English ed.) (01-10-2022)“…The publication of the EMPEROR-Preserved trial and data on the benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with heart failure…”
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Empagliflozin Ameliorates Diastolic Dysfunction and Left Ventricular Fibrosis/Stiffness in Nondiabetic Heart Failure
Published in JACC. Cardiovascular imaging (01-02-2021)“…The purpose of this study was to investigate the effect of empagliflozin on diastolic function in a nondiabetic heart failure with reduced ejection fraction…”
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EMPAGLIFLOZIN INDUCES A MYOCARDIAL METABOLIC SHIFT FROM GLUCOSE CONSUMPTION TO KETONE METABOLISM THAT MITIGATES ADVERSE CARDIAC REMODELING AND IMPROVES MYOCARDIAL CONTRACTILITY
Published in Journal of the American College of Cardiology (10-03-2018)“…Given that EMPA causes mild, persistent hyperketonemia, we hypothesized that cardiac benefits of EMPA are due to a shift in myocardial fuel metabolism away…”
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Clinical Prognosis Associated With the Use of Overlapping Stents With Homogenous Versus Heterogeneous Pharmacological Characteristics for the Treatment of Diffuse Coronary Artery Disease
Published in Cardiovascular revascularization medicine (01-11-2020)“…The clinical impact of percutaneous coronary intervention (PCI) and implantation of overlapping stents (OS) using platforms with the same versus different…”
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Inhibición dual del SGLT1 y SGLT2: algo más que su suma
Published in Revista española de cardiologia (01-07-2024)Get full text
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High-density lipoprotein cholesterol: a new marker in heart failure
Published in Revista española de cardiología (English ed.) (01-11-2022)Get full text
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Mechanistic Insights of Empagliflozin in Nondiabetic Patients With HFrEF
Published in JACC. Heart failure (01-08-2021)Get full text
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HDL: un nuevo biomarcador para la insuficiencia cardiaca
Published in Revista española de cardiologia (01-11-2022)Get full text
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