Search Results - "Repouskou, Anastasia"
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Long term transcriptional and behavioral effects in mice developmentally exposed to a mixture of endocrine disruptors associated with delayed human neurodevelopment
Published in Scientific reports (09-06-2020)“…Accumulating evidence suggests that gestational exposure to endocrine disrupting chemicals (EDCs) may interfere with normal brain development and predispose…”
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Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes
Published in Scientific reports (23-04-2019)“…The increasing concern for the reproductive toxicity of abundantly used phthalates requires reliable tools for exposure risk assessment to mixtures of…”
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c-MYC targets the central oscillator gene Per1 and is regulated by the circadian clock at the post-transcriptional level
Published in Biochimica et biophysica acta (01-04-2016)“…Cell proliferation in mammals follows a circadian rhythm while disruption of clock gene expression has been linked to tumorigenesis. Expression of the c-Myc…”
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In utero exposure to phthalates and reproductive toxicity in rodents
Published in Baillière's best practice & research. Clinical endocrinology & metabolism (01-09-2021)“…Phthalates, widely used as plasticizers, are contained in many everyday products. Human biomonitoring studies detect their presence in biological fluids of a…”
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Synergistic effects of early life mild adversity and chronic social defeat on rat brain microglia and cytokines
Published in Physiology & behavior (01-03-2020)“…•Mild early life stress primes microglia and alters its later response to stress.•Mild ELS reduces PPARγ expression in the hippocampus.•Mild ELS followed by…”
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A human-relevant mixture of endocrine disrupting chemicals induces changes in hippocampal DNA methylation correlating with hyperactive behavior in male mice
Published in Chemosphere (Oxford) (01-02-2023)“…Humans are ubiquitously exposed to endocrine disrupting chemicals (EDCs), substances that interfere with endogenous hormonal signaling. Exposure during early…”
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The circadian expression of c-MYC is modulated by the histone deacetylase inhibitor trichostatin A in synchronized murine neuroblastoma cells
Published in Chronobiology international (01-05-2010)“…Circadian clocks govern the mammalian physiology in a day/night-dependent manner. The circadian oscillator of peripheral organs is composed of the same…”
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