Search Results - "Repkova, Marina N."

High antiviral effect of TiO2·PL–DNA nanocomposites targeted to conservative regions of (−)RNA and (+)RNA of influenza A virus in cell culture by Levina, Asya S, Repkova, Marina N, Bessudnova, Elena V, Filippova, Ekaterina I, Mazurkova, Natalia A, Zarytova, Valentina F

“…Summary Background: The development of new antiviral drugs based on nucleic acids is under scrutiny. An important problem in this aspect is to find the most…”
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Non-agglomerated silicon-organic nanoparticles and their nanocomplexes with oligonucleotides: synthesis and properties by Levina, Asya S, Repkova, Marina N, Shikina, Nadezhda V, Ismagilov, Zinfer R, Yashnik, Svetlana A, Semenov, Dmitrii V, Savinovskaya, Yulia I, Mazurkova, Natalia A, Pyshnaya, Inna A, Zarytova, Valentina F

“…The development of efficient and convenient systems for the delivery of nucleic-acid-based drugs into cells is an urgent task. А promising approach is the use…”
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Substantial Antiviral Potential of Deoxyribozymes Fixed on Anatase Nanoparticles Against Influenza A Viruses in vitro and in vivo by Levina, Asya S, Repkova, Marina N, Netesova, Nina A, Ternovoi, Vladimir A, Mazurkov, Oleg Yu, Filippova, Ekaterina I, Mazurkova, Natalia A, Zarytova, Valentina F

“…Influenza A viruses (IAV) are a high threat to humanity because of a lack of proper effective antiviral drugs and resistance of viruses to existing vaccines…”
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Knockdown of different influenza A virus subtypes in cell culture by a single antisense oligodeoxyribonucleotide by Levina, Asya S, Repkova, Marina N, Mazurkova, Natalia A, Makarevich, Elena V, Ismagilov, Zinfer R, Zarytova, Valentina F

“…Highlights • A single oligonucleotide efficiently inhibited various influenza A virus (IAV) strains. • Oligonucleotide is delivered into cells in a TiO2…”
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Nanocomposites consisting of titanium dioxide nanoparticles, antisense oligonucleotides, and photoactive groups as agents for effective action on nucleic acids by Levina, Asya S., Repkova, Marina N., Mazurkov, Oleg Y., Makarevich, Elena V., Mazurkova, Natalya A., Zarytova, Valentina F.

“…Relevance. Studies on model systems have confirmed the effectiveness of antisense oligonucleotides, including those that contain photoactive groups, for the…”
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Nanoparticle-Mediated Nonviral DNA Delivery for Effective Inhibition of Influenza a Viruses in Cells by Levina, Asya S., Repkova, Marina N., Mazurkova, Natalia A., Zarytova, Valentina F.

“…Development of new antiviral nucleic acid-based drugs and the search for their efficient delivery into cells are an urgent task. We prepared the TiO2·PL-DNA…”
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SiO2 nanoparticles as platform for delivery of 3′-triazole analogues of AZT-triphosphate into cells by Vasilyeva, Svetlana V., Levina, Asya S., Li-Zhulanov, Nikolai S., Shatskaya, Natalia V., Baiborodin, Sergei I., Repkova, Marina N., Zarytova, Valentina F., Mazurkova, Natalia A., Silnikov, Vladimir N.

“…[Display omitted] A system for delivery of analogues of AZT-triphosphates (AZT*TP) based on SiO2 nanoparticles was proposed. For this purpose, a simple and…”
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High-performance method for specific effect on nucleic acids in cells using TiO2~DNA nanocomposites by Levina, Asya S., Repkova, Marina N., Ismagilov, Zinfer R., Shikina, Nadezhda V., Malygin, Ernst G., Mazurkova, Natalia A., Zinov'ev, Victor V., Evdokimov, Alexei A., Baiborodin, Sergei I., Zarytova, Valentina F.

“…Nanoparticles are used to solve the current drug delivery problem. We present a high-performance method for efficient and selective action on nucleic acid…”
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SiO2 nanoparticles as platform for delivery of nucleoside triphosphate analogues into cells by Vasilyeva, Svetlana V., Silnikov, Vladimir N., Shatskaya, Natalia V., Levina, Asya S., Repkova, Marina N., Zarytova, Valentina F.

“…A system for delivery of analogues of 2′-deoxyribonucleoside triphosphate (dNTP) based on SiO2 nanoparticles was proposed. A simple and versatile method was…”
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Positioning of the mRNA stop signal with respect to polypeptide chain release factors and ribosomal proteins in 80S ribosomes by Bulygin, Konstantin N, Repkova, Marina N, Ven’yaminova, Aliya G, Graifer, Dmitri M, Karpova, Galina G, Frolova, Ludmila Yu, Kisselev, Lev L

“…To study positioning of the mRNA stop signal with respect to polypeptide chain release factors (RFs) and ribosomal components within human 80S ribosomes,…”
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High antiviral effect of TiO 2 ·PL-DNA nanocomposites targeted to conservative regions of (-)RNA and (+)RNA of influenza A virus in cell culture by Levina, Asya S, Repkova, Marina N, Bessudnova, Elena V, Filippova, Ekaterina I, Mazurkova, Natalia A, Zarytova, Valentina F

“…The development of new antiviral drugs based on nucleic acids is under scrutiny. An important problem in this aspect is to find the most vulnerable…”
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Nucleotide G-1207 of 18S rRNA is an essential component of the human 80S ribosomal decoding center by Bulygin, K N, Graifer, D M, Repkova, M N, Smolenskaya, I A, Veniyaminova, A G, Karpova, G G

“…mRNA analogues-derivatives of oligoribonucleotides consisting of two different codons and bearing an aryl azide group at the 5'-phosphates-were crosslinked to…”
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TiO2∼DNA nanocomposites as efficient site-specific antiviral agents against influenza A virus in cell culture by Levina, Asya S., Repkova, Marina N., Zarytova, Valentina F., Mazurkova, Natalia A.

“…The development of new antiviral nucleic acid-based drugs and the search for their efficient delivery into cells are an urgent task. We developed methods of…”
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Proteins neighboring 18S rRNA conserved sequences 609–618 and 1047–1061 within the 40S human ribosomal subunit by MALYGIN, ALEXEY A., DOBRIKOV, MIKHAIL I., REPKOVA, MARINA N., SHISHKIN, GENNADI V., VEN'YAMINOVA, ALIYA G., KARPOVA, GALINA G.

“…The structure of human 40S ribosomal subunits has been probed by a cross-linking strategy based on the use of oligonucleotide derivatives that modify proteins…”
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Interaction of primer tRNA(Lys3) with the p51 subunit of human immunodeficiency virus type 1 reverse transcriptase: a possible role in enzyme activation by Zakharova, O D, Tarrago-Litvak, L, Fournier, M, Andreola, M L, Repkova, M N, Venyaminova, A G, Litvak, S, Nevinsky, G A

“…In the interaction between HIV-1 RT and tRNA(Lys3) each subunit of the heterodimer interacts with tRNA showing a different affinity: Kd (p66) = 23 nM, Kd (p51)…”
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Interaction of primer tRNALys3 with the p51 subunit of human immunodeficiency virus type 1 reverse transcriptase: a possible role in enzyme activation by Zakharova, Olga D., Tarrago-Litvak, Laura, Fournier, Michel, Andreola, Marie Line, Repkova, Marina N., Venyaminova, Alija G., Litvak, Simon, Nevinsky, Georgyi A.

“…In the interaction between HIV‐1 RT and tRNALys3 each subunit of the heterodimer interacts with tRNA showing a different affinity: K d (p66) = 23 nM, K d (p51)…”
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Interaction of primer tRNA Lys3 with the p51 subunit of human immunodeficiency virus type 1 reverse transcriptase: a possible role in enzyme activation by Zakharova, Olga D., Tarrago-Litvak, Laura, Fournier, Michel, Andreola, Marie Line, Repkova, Marina N., Venyaminova, Alija G., Litvak, Simon, Nevinsky, Georgyi A.

“…In the interaction between HIV-1 RT and tRNA Lys3 each subunit of the heterodimer interacts with tRNA showing a different affinity: K d (p66) = 23 nM, K d…”
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