Search Results - "Repka, M. A."

A novel thermosensitive polymer with pH-dependent degradation for drug delivery by Garripelli, V.K., Kim, J.-K., Namgung, R., Kim, W.J., Repka, M.A., Jo, S.

“…A class of thermosensitive biodegradable multiblock copolymers with acid-labile acetal linkages were synthesized from Pluronic ® triblock copolymers (Pluronic…”
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Influence of Tartaric Acid on the Bioadhesion and Mechanical Properties of Hot-Melt Extruded Hydroxypropyl Cellulose Films for the Human Nail by Mididoddi, P. K., Prodduturi, S., Repka, M. A.

“…ABSTRACT The objective of this study was to investigate the influence of tartaric acid (TTA) on the bioadhesive, moisture sorption, and mechanical properties…”
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Stability of Vaccines by Dumpa, N., Goel, K., Guo, Yuhan, McFall, H., Pillai, Amit Raviraj, Shukla, Ashay, Repka, M. A., Murthy, S. Narasimha

“…Vaccines are considered the most economical and effective preventive measure against most deadly infectious diseases. Vaccines help protect around three…”
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Effect of surfactant on quality and performance attributes of topical semisolids by Kumar Sharma, Purnendu, Panda, A., Parajuli, S., Badani Prado, R.M., Kundu, S., Repka, M.A., Ureña-Benavides, E., Narasimha Murthy, S.

“…[Display omitted] Surfactants are the most common inactive ingredients used in topical drug products. Surfactants in topical products play many functional…”
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Influence of Vitamin E TPGS on the properties of hydrophilic films produced by hot-melt extrusion by Repka, Michael A, McGinity, James W

“…Films containing hydroxypropylcellulose (HPC) and polyethylene oxide (PEO) were prepared using a Randcastle extruder (Model 750) with and without Vitamin E…”
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Interactions Between Biological Products and Product Packaging and Potential Approaches to Overcome Them by Wang, Minjia, Li, Yusheng, Srinivasan, Priyanka, Hu, Zhiqing, Wang, Rui, Saragih, Anggrida, Repka, M. A., Murthy, S. N.

“…Biological products such as protein-based biopharmaceuticals are playing an important role in the healthcare and pharmaceutical industry. The interaction…”
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Influence of Plasticizers and Drugs on the Physical-Mechanical Properties of Hydroxypropylcellulose Films Prepared by Hot Melt Extrusion by Repka, Michael A., Gerding, Thomas G., Repka, Staci L., McGinity, James W.

“…Hydroxypropylcellulose (HPC) films containing drugs or hydrophilic or hydrophobic plasticizers were prepared by a hot melt extrusion process. Polyethylene…”
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Transungual drug delivery: an update by Shivakumar, H.N., Repka, M.A., Narasimha Murthy, S.

“…Topical therapy continues to be the treatment of choice for the patients and clinicians in treating certain infections of the nails. Topical treatment is…”
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Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods by Thumma, S, Repka, M A

“…The compatibility of promethazine hydrochloride (PMZ) with various tableting excipients has been investigated by isothermal stress testing (IST) and…”
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Pre-treatment with chemical penetration enhancers in dermal/transdermal drug delivery by Maurya, A., Repka, M.A., Cegu, P., Narasimha Murthy, S.

“…Delivery of drugs through skin is an alternative route of drug administration. However dermal/transdermal delivery of drugs is limited by the exceptional…”
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Preparation and anti-bacterial properties of a temperature-sensitive gel containing silver nanoparticles by Chen, Meiwan, Pan, Xin, Wu, Hongmei, Han, Ke, Xie, Xiaobao, Wedge, D E, Repka, M A, Wu, Chuanbin

“…The purpose of this study was to prepare a temperature-sensitive gel containing silver nanoparticles and to investigate its anti-bacterial properties in vitro…”
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Accurate determination of the time of cell birth using a sequential labeling technique with [3H]-thymidine and bromodeoxyuridine ("window labeling") by Repka, AM, Adler, R

“…During tissue embryogenesis, precursor cells divide actively and eventually withdraw from the mitotic cycle before differentiation. Accurate information about…”
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Application of co-grinding to formulate a model pMDI suspension by WILLIAMS, R. O, REPKA, M. A, BARRON, M. K

“…The objective of this study was to investigate the effect of co-grinding the model drug, triamcinolone acetonide (TAA), with a polymeric surfactant on the in…”
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Development and validation of a HPLC method for the analysis of promethazine hydrochloride in hot-melt extruded dosage forms by Thumma, S, Zhang, Shuang-Qing, Repka, M A

“…A simple and rapid stability-indicating HPLC method was developed for determination of promethazine hydrochloride (PMZ) in hot-melt extruded (HME) films and…”
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Bioadhesive properties of hydroxypropylcellulose topical films produced by hot-melt extrusion by Repka, Michael A, McGinity, James W

“…The objective of this study was to investigate the in vivo bioadhesive properties of hydroxypropylcellulose (HPC) films containing seven polymer additives on…”
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Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens by Boddu, S P, Yamsani, M Rao, Potharaju, S, Veeraraghavan, S, Rajak, S, Kuma, S V V S, Avery, B A, Repka, M A, Varanasi, V S K Kiran

“…Drug efflux by intestinal P-glycoprotein (P-gp) is recognized as a significant biochemical barrier affecting oral absorption for a number of drugs apart from…”
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Development and characterization of taste masked Efavirenz pellets utilizing hot melt extrusion by Singh, A., Majumdar, S., Deng, W., Mohammed, N.N., Chittiboyina, A.G., Raman, V., Shah, S., Repka, M.A.

“…The objective of this study was to formulate taste-masked pellets of Efavirenz (EFZ) with Eudragit E PO as the matrix polymer utilizing hot melt extrusion…”
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Solid-state stability and characterization of hot-melt extruded poly(ethylene oxide) films by Prodduturi, Suneela, Manek, Rahul V, Kolling, William M, Stodghill, Steven P, Repka, Michael A

“…Poly(ethylene oxide) (PEO) was used to prepare thin polymer films containing clotrimazole (CT) utilizing hot-melt extrusion (HME) technology. Films containing…”
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Physical–mechanical, moisture absorption and bioadhesive properties of hydroxypropylcellulose hot-melt extruded films by Repka, Michael A., McGinity, James W.

“…The objective of this study was to investigate the moisture absorption, physical–mechanical and bioadhesive properties of hot-melt extruded…”
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The influence of guaifenesin and ketoprofen on the properties of hot-melt extruded polyethylene oxide films by Crowley, Michael M, Fredersdorf, Anke, Schroeder, Britta, Kucera, Shawn, Prodduturi, Suneela, Repka, Michael A, McGinity, James W

“…Films containing polyethylene oxide (PEO) and a model drug, either guaifenesin (GFN) or ketoprofen (KTP), were prepared by hot-melt extrusion. The thermal…”
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