Search Results - "Renzulli, Cecilia"
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Rifaximin: beyond the traditional antibiotic activity
Published in Journal of antibiotics (01-09-2014)“…Rifaximin is a non-systemic oral antibiotic derived from rifampin and characterized by a broad spectrum of antibacterial activity against Gram-positive and…”
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Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention
Published in Frontiers in pharmacology (29-11-2018)“…Non-steroidal anti-inflammatory drugs (NSAIDs) can damage the small intestine, mainly through an involvement of enteric bacteria. This study examined the…”
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Small bowel protection against NSAID-injury in rats: Effect of rifaximin, a poorly absorbed, GI targeted, antibiotic
Published in Pharmacological research (01-02-2016)“…[Display omitted] Nonsteroidal anti-inflammatory drugs, besides exerting detrimental effects on the upper digestive tract, can also damage the small and large…”
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Evaluation of Antioxidant Activity of Some Natural Polyphenolic Compounds Using the Briggs−Rauscher Reaction Method
Published in Journal of agricultural and food chemistry (18-12-2002)“…A new method based on the inhibitory effects of antioxidants on the oscillations of the hydrogen peroxide, acidic iodate, malonic acid, and Mn(II)-catalyzed…”
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Disposition and Metabolism of [14C]SB-649868, an Orexin 1 and 2 Receptor Antagonist, in Humans
Published in Drug metabolism and disposition (01-02-2011)“…N-[[(2S)-1-[[5-(4-fluorophenyl)-2-methyl-4-thiazolyl]carbonyl]-2-piperidinyl]methyl]-4-benzofurancarboxamide (SB-649868) is a novel orexin 1 and 2 receptor…”
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Rifaximin Reduces the Number and Severity of Intestinal Lesions Associated With Use of Nonsteroidal Anti-Inflammatory Drugs in Humans
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)“…The intestinal microbiota might contribute to enteropathy associated with use of nonsteroidal anti-inflammatory drugs (NSAIDs), but there have been few human…”
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Velusetrag accelerates gastric emptying in subjects with gastroparesis: a multicentre, double‐blind, randomised, placebo‐controlled, phase 2 study
Published in Alimentary pharmacology & therapeutics (01-05-2021)“…Summary Background Gastroparesis is a serious gastrointestinal (GI) condition characterised by delayed gastric emptying (GE). Velusetrag—a potent, selective,…”
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Editorial: on the road towards treatment of gastroparesis—accelerating, but do we get closer? Authors' reply
Published in Alimentary pharmacology & therapeutics (01-07-2021)“…LINKED CONTENT This article is linked to Kuo et al and Wuestenberghs & Gourcerol papers. To view these articles, visit https://doi.org/10.1111/apt.16344 and…”
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A randomized, double‐blind, placebo‐controlled, phase 2b study of the efficacy and safety of velusetrag in subjects with diabetic or idiopathic gastroparesis
Published in Neurogastroenterology and motility (01-04-2023)“…Background This study assessed the efficacy and safety of velusetrag—a 5‐HT4 agonist with pan‐gastrointestinal prokinetic activity—for gastroparesis symptom…”
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The Relationship Between Endoscopic and Clinical Recurrence in Postoperative Crohn’s Disease: A Systematic Review and Meta-analysis
Published in Journal of Crohn's and colitis (14-03-2022)“…Abstract Background and Aims We aimed to quantify the magnitude of the association between endoscopic recurrence and clinical recurrence [symptom relapse] in…”
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Rifaximin Reduces Number and Severity of Intestinal Lesions Associated With use of Non-steroidal Anti-inflammatory Drugs in Humans
Published in Gastroenterology (New York, N.Y. 1943) (2016)“…Abstract The intestinal microbiota might contribute to enteropathy associated with use of non-steroidal anti-inflammatory drugs (NSAIDs), but there have been…”
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Su1193 Rifaximin Prevents Enteric Bacteria Alterations and Inflammation in a Rat Model of Diclofenac-Induced Enteropathy
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)Get full text
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398 Rifaximin Displays a Protective Activity in Experimental Enteropathy Induced by Indomethacin in Rats
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2015)Get full text
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