Search Results - "Rentzsch, Fabian"
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Genomics and development of Nematostella vectensis and other anthozoans
Published in Current opinion in genetics & development (01-08-2016)“…Due to their rather simple body plan with only few organs and a low number of cell types, cnidarians have long been recognized as an important animal group for…”
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Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis
Published in Nature communications (24-01-2022)“…Chromatin regulation is a key process in development but its contribution to the evolution of animals is largely unexplored. Chromatin is regulated by a…”
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RGM regulates BMP-mediated secondary axis formation in the sea anemone Nematostella vectensis
Published in Cell reports (Cambridge) (11-12-2014)“…Patterning of the metazoan dorsoventral axis is mediated by a complex interplay of BMP signaling regulators. Repulsive guidance molecule (RGM) is a conserved…”
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The bilaterian head patterning gene six3/6 controls aboral domain development in a cnidarian
Published in PLoS biology (01-02-2013)“…The origin of the bilaterian head is a fundamental question for the evolution of animal body plans. The head of bilaterians develops at the anterior end of…”
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Making head or tail of cnidarian hox gene function
Published in Nature communications (05-06-2018)“…Distantly related animals have spectacularly different shapes and body plans, which can render it difficult to understand which of their body parts may have a…”
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Molecular characterization of the apical organ of the anthozoan Nematostella vectensis
Published in Developmental biology (01-02-2015)“…Apical organs are sensory structures present in many marine invertebrate larvae where they are considered to be involved in their settlement, metamorphosis and…”
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A cnidarian homologue of an insect gustatory receptor functions in developmental body patterning
Published in Nature communications (18-02-2015)“…Insect gustatory and odorant receptors (GRs and ORs) form a superfamily of novel transmembrane proteins, which are expressed in chemosensory neurons that…”
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Back to the Basics: Cnidarians Start to Fire
Published in Trends in neurosciences (Regular ed.) (01-02-2017)“…The nervous systems of cnidarians, pre-bilaterian animals that diverged close to the base of the metazoan radiation, are structurally simple and thus have…”
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A developmental role for the chromatin-regulating CoREST complex in the cnidarian Nematostella vectensis
Published in BMC biology (23-08-2022)“…Chromatin-modifying proteins are key players in the regulation of development and cell differentiation in animals. Most chromatin modifiers, however, predate…”
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Cnidarian microRNAs frequently regulate targets by cleavage
Published in Genome research (01-04-2014)“…In bilaterians, which comprise most of extant animals, microRNAs (miRNAs) regulate the majority of messenger RNAs (mRNAs) via base-pairing of a short sequence…”
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NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis
Published in Nature communications (10-08-2023)“…Neurogenesis has been studied extensively in the ectoderm, from which most animals generate the majority of their neurons. Neurogenesis from non-ectodermal…”
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FGF signalling controls formation of the apical sensory organ in the cnidarian Nematostella vectensis
Published in Development (Cambridge) (15-05-2008)“…Fibroblast growth factor (FGF) signalling regulates essential developmental processes in vertebrates and invertebrates, but its role during early metazoan…”
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Doublecortin-like kinase is required for cnidocyte development in Nematostella vectensis
Published in Neural development (22-06-2024)“…The complex morphology of neurons requires precise control of their microtubule cytoskeleton. This is achieved by microtubule-associated proteins (MAPs) that…”
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Zebrafish Bmp4 regulates left–right asymmetry at two distinct developmental time points
Published in Developmental biology (15-05-2007)“…Left–right (LR) asymmetry is regulated by early asymmetric signals within the embryo. Even though the role of the bone morphogenetic protein (BMP) pathway in…”
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Wnt/β-Catenin and noncanonical Wnt signaling interact in tissue evagination in the simple eumetazoan Hydra
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-2009)“…In and evaginations of 2D cell sheets are major shape generating processes in animal development. They result from directed movement and intercalation of…”
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Bmp and Fgf signaling are essential for liver specification in zebrafish
Published in Development (Cambridge) (01-06-2007)“…Based on data from in vitro tissue explant and ex vivo cell/bead implantation experiments, Bmp and Fgf signaling have been proposed to regulate hepatic…”
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BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway
Published in Cell stem cell (01-01-2008)“…The formation of blood in the embryo is dependent on bone morphogenetic protein (BMP), but how BMP signaling intersects with other regulators of hematopoietic…”
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Asymmetric expression of the BMP antagonists chordin and gremlin in the sea anemone Nematostella vectensis: Implications for the evolution of axial patterning
Published in Developmental biology (15-08-2006)“…The evolutionary origin of the anterior–posterior and the dorsoventral body axes of Bilateria is a long-standing question. It is unclear how the main body axis…”
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Repeated evolution of identical domain architecture in metazoan netrin domain-containing proteins
Published in Genome biology and evolution (01-01-2012)“…The majority of proteins in eukaryotes are composed of multiple domains, and the number and order of these domains is an important determinant of protein…”
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A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons
Published in Nature ecology & evolution (01-04-2019)“…The mechanisms by which entire programmes of gene regulation emerged during evolution are poorly understood. Neuronal microexons represent the most conserved…”
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