Search Results - "Rentzsch, C"

458P - Safety, efficacy, PK and PD biomarker results of the first-in-human study of mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor BAY 1436032 in patients (pts) with mIDH1 advanced solid tumours by Wick, W., Tabatabai, G., Schuler, M., Rorhberg, K., Chawla, S.P., Janku, F., Schiff, D., Heinemann, V., Narita, Y., Ando, Y., Lenz, H.J., Ikeda, M., Genvresse, I., Rentzsch, C., Reschke, S., Cyris, C., Cai, C., Jeffers, M., Peña, C., Bähr, O.

“…BAY 1436032 (BAY) inhibits R132X-mIDH1, which aberrantly generates oncometabolite 2-hydroxyglutarate (2-HG). In animal studies, BAY decreased 2-HG levels in…”
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Safety, efficacy, PK and PD biomarker results of the first-in-human study of mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor BAY 1436032 in patients (pts) with mIDH1 advanced solid tumours by Wick, W., Tabatabai, G., Schuler, M., Rorhberg, K., Chawla, S.P., Janku, F., Schiff, D., Heinemann, V., Narita, Y., Ando, Y., Lenz, H.J., Ikeda, M., Genvresse, I., Rentzsch, C., Reschke, S., Cyris, C., Cai, C., Jeffers, M., Peña, C., Bähr, O.

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Development, monitoring and first immunological results of a phase I/II vaccination trial using genetically modified allogeneic breast cancer cells by Gückel, B, Stumm, S, Rentzsch, C, Kayser, S, Gruber, I, Marmé, A, Huober, J, Autschbach, F, Meuer, S, Wallwiener, D

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458PSafety, efficacy, PK and PD biomarker results of the first-in-human study of mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor BAY 1436032 in patients (pts) with mIDH1 advanced solid tumours by Wick, W, Tabatabai, G, Schuler, M, Rorhberg, K, Chawla, S P, Janku, F, Schiff, D, Heinemann, V, Narita, Y, Ando, Y, Lenz, H J, Ikeda, M, Genvresse, I, Rentzsch, C, Reschke, S, Cyris, C, Cai, C, Jeffers, M, Peña, C, Bähr, O

“…Abstract Background BAY 1436032 (BAY) inhibits R132X-mIDH1, which aberrantly generates oncometabolite 2-hydroxyglutarate (2-HG). In animal studies, BAY…”
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Evaluation of pre-existent immunity in patients with primary breast cancer: Molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells by RENTZSCH, Christine, KAYSER, Simone, STUMM, Susanne, WATERMANN, Iris, WALTER, Steffen, STEVANOVIC, Stefan, WALLWIENER, Diethelm, GÜCKEL, Brigitte

“…Breast cancers are known to frequently (over)express several well-characterized tumor-associated antigens (TAAs) such as carcinoembryonic antigen, MUC-1,…”
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A CD80-transfected human breast cancer cell variant induces HER-2/neu-specific T cells in HLA-A02-matched situations in vitro as well as in vivo by GÜCKEL, Brigitte, STUMM, Susanne, RENTZSCH, Christine, MARME, Alexander, MANNHARDT, Geeske, WALLWIENER, Diethelm

“…Adjuvant treatment is still only working in a small percentage of breast cancer patients. Therefore, new strategies need to be developed. Immunotherapies are a…”
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Pre-existing T-cell immunity against mucin-1 in breast cancer patients and healthy volunteers by GUCKEL, Brigitte, RENTZSCH, Christine, NASTKE, Maria-Dorothea, MARME, Alexander, GRUBER, Ines, STEVANOVIC, Stefan, KAYSER, Simone, WALLWIENER, Diethelm

“…There is evidence that some tumor patients are able to generate tumor-associated antigen (TAA)-specific T-cell immunity spontaneously. However, little is…”
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Pathogenesis of Borna Disease Virus: Granulocyte Fractions of Psychiatric Patients Harbor Infectious Virus in the Absence of Antiviral Antibodies by Planz, O, Rentzsch, C, Batra, A, Winkler, T, Büttner, M, Rziha, H J, Stitz, L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tumor-associated antigen profiling in breast and ovarian cancer: mRNA, protein or T cell recognition? by KAYSER, Simone, WATERMANN, Iris, RENTZSCH, Christine, WEINSCHENK, Toni, WALLWIENER, Diethelm, GÜCKEL, Brigitte

“…The absence of tumor-associated antigens (TAA) which might elicit an immune response is one reason for the disappointing results of therapeutical vaccines in…”
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Persistence of Borna disease virus-specific nucleic acid in blood of psychiatric patient by Planz, Oliver, Rentzsch, Christine, Batra, Anil, Rziha, Hanns-Joachim, Stitz, Lothar

“…Planz et al's study indicates that both p24-specific and p40-specific mRNA can be detected in the blood of patients with a psychiatric disorder over eight…”
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CD80-modified tumor cell lines: implications for cell-based vaccinations in breast cancer patients by Gückel, B, Stumm, S, Kayser, S, Rentzsch, C, Gruber, I, Marmé, A, Huober, J, Meuer, S C, Wallwiener, D

“…A number of genetic alterations are required for malignant transformation. However, these mutations provide the source for tumor-associated antigens which can…”
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Persistence of Borna disease virus-specific nucleic acid in blood of psychiatric patient by Planz, O, Rentzsch, C, Batra, A, Rziha, H-J, Stitz, L

“…Evidence of Borna disease virus (BDV) in patients with psychiatric diseases has been found by several researchers; BDV-specific antigen and nucleic acid has…”
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Persistence of Borna disease virus-specific nucleic acid in blood of psychiatric patient by Planz, O, Rentzsch, C, Batra, A, Rziha, H J, Stitz, L

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