Search Results - "Rentsch, Christopher T."

Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans: A nationwide cohort study by Rentsch, Christopher T, Kidwai-Khan, Farah, Tate, Janet P, Park, Lesley S, King, Jr, Joseph T, Skanderson, Melissa, Hauser, Ronald G, Schultze, Anna, Jarvis, Christopher I, Holodniy, Mark, Lo Re, 3rd, Vincent, Akgün, Kathleen M, Crothers, Kristina, Taddei, Tamar H, Freiberg, Matthew S, Justice, Amy C

“…There is growing concern that racial and ethnic minority communities around the world are experiencing a disproportionate burden of severe acute respiratory…”
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Development and validation of a 30-day mortality index based on pre-existing medical administrative data from 13,323 COVID-19 patients: The Veterans Health Administration COVID-19 (VACO) Index by King, Jr, Joseph T, Yoon, James S, Rentsch, Christopher T, Tate, Janet P, Park, Lesley S, Kidwai-Khan, Farah, Skanderson, Melissa, Hauser, Ronald G, Jacobson, Daniel A, Erdos, Joseph, Cho, Kelly, Ramoni, Rachel, Gagnon, David R, Justice, Amy C

“…Available COVID-19 mortality indices are limited to acute inpatient data. Using nationwide medical administrative data available prior to SARS-CoV-2 infection…”
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Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study by Rentsch, Christopher T, Beckman, Joshua A, Tomlinson, Laurie, Gellad, Walid F, Alcorn, Charles, Kidwai-Khan, Farah, Skanderson, Melissa, Brittain, Evan, King, Jr, Joseph T, Ho, Yuk-Lam, Eden, Svetlana, Kundu, Suman, Lann, Michael F, Greevy, Jr, Robert A, Ho, P Michael, Heidenreich, Paul A, Jacobson, Daniel A, Douglas, Ian J, Tate, Janet P, Evans, Stephen J W, Atkins, David, Justice, Amy C, Freiberg, Matthew S

“…To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among…”
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Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February by Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen Jw, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Ys, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M

“…The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is…”
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Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England by Grint, Daniel J, Wing, Kevin, Houlihan, Catherine, Gibbs, Hamish P, Evans, Stephen J W, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Y S, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Smeeth, Liam, Goldacre, Ben, Eggo, Rosalind M

“…Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) alpha variant (B.1.1.7) is associated with higher transmissibility than…”
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Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform by Bhaskaran, Krishnan, Rentsch, Christopher T, Hickman, George, Hulme, William J, Schultze, Anna, Curtis, Helen J, Wing, Kevin, Warren-Gash, Charlotte, Tomlinson, Laurie, Bates, Chris J, Mathur, Rohini, MacKenna, Brian, Mahalingasivam, Viyaasan, Wong, Angel, Walker, Alex J, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Parry, John, Hester, Frank, Harper, Sam, Evans, Stephen Jw, Bacon, Sebastian, Smeeth, Liam, Goldacre, Ben

“…There is concern about medium to long-term adverse outcomes following acute Coronavirus Disease 2019 (COVID-19), but little relevant evidence exists. We aimed…”
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HbA1c and brain health across the entire glycaemic spectrum by Garfield, Victoria, Farmaki, Aliki‐Eleni, Eastwood, Sophie V., Mathur, Rohini, Rentsch, Christopher T., Bhaskaran, Krishnan, Smeeth, Liam, Chaturvedi, Nish

“…Aim To understand the relationship between HbA1c and brain health across the entire glycaemic spectrum. Materials and Methods We used data from the UK Biobank…”
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Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform by Bhaskaran, Krishnan, Bacon, Sebastian, Evans, Stephen JW, Bates, Chris J, Rentsch, Christopher T, MacKenna, Brian, Tomlinson, Laurie, Walker, Alex J, Schultze, Anna, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Curtis, Helen J, Hulme, William J, Parry, John, Hester, Frank, Harper, Sam, Spiegelhalter, David, Smeeth, Liam, Goldacre, Ben

“…Mortality from COVID-19 shows a strong relationship with age and pre-existing medical conditions, as does mortality from other causes. We aimed to investigate…”
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Geographic and temporal variation in racial and ethnic disparities in SARS-CoV-2 positivity between February 2020 and August 2021 in the United States by Ferguson, Jacqueline M., Justice, Amy C., Osborne, Thomas F., Magid, Hoda S. Abdel, Purnell, Amanda L., Rentsch, Christopher T.

“…The coronavirus pandemic has disproportionally impacted racial and ethnic minority communities in the United States. Patterns of these disparities may be…”
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Effects of topiramate therapy on serum bicarbonate concentration in a sample of 10,279 veterans by Naps, Michelle S., Leong, Shirley H., Hartwell, Emily E., Rentsch, Christopher T., Kranzler, Henry R.

“…Background Topiramate, which is increasingly being used to treat alcohol use disorder (AUD), is commonly associated with reduced serum bicarbonate…”
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Survival analysis of localized prostate cancer with deep learning by Dai, Xin, Park, Ji Hwan, Yoo, Shinjae, D’Imperio, Nicholas, McMahon, Benjamin H., Rentsch, Christopher T., Tate, Janet P., Justice, Amy C.

“…In recent years, data-driven, deep-learning-based models have shown great promise in medical risk prediction. By utilizing the large-scale Electronic Health…”
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Core Concepts in Pharmacoepidemiology: Quantitative Bias Analysis by Brown, Jeremy P., Hunnicutt, Jacob N., Ali, M. Sanni, Bhaskaran, Krishnan, Cole, Ashley, Langan, Sinead M., Nitsch, Dorothea, Rentsch, Christopher T., Galwey, Nicholas W., Wing, Kevin, Douglas, Ian J.

“…ABSTRACT Pharmacoepidemiological studies provide important information on the safety and effectiveness of medications, but the validity of study findings can…”
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UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records by Walker, Jemma L, Grint, Daniel J, Strongman, Helen, Eggo, Rosalind M, Peppa, Maria, Minassian, Caroline, Mansfield, Kathryn E, Rentsch, Christopher T, Douglas, Ian J, Mathur, Rohini, Wong, Angel Y S, Quint, Jennifer K, Andrews, Nick, Bernal, Jamie Lopez, Scott, J Anthony, Ramsay, Mary, Smeeth, Liam, McDonald, Helen I

“…Characterising the size and distribution of the population at risk of severe COVID-19 is vital for effective policy and planning. Older age, and underlying…”
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Social determinants of pertussis and influenza vaccine uptake in pregnancy: a national cohort study in England using electronic health records by Walker, Jemma L, Rentsch, Christopher T, McDonald, Helen I, Bak, JeongEun, Minassian, Caroline, Amirthalingam, Gayatri, Edelstein, Michael, Thomas, Sara

“…ObjectiveTo examine the social determinants of influenza and pertussis vaccine uptake among pregnant women in England.DesignNationwide population-based cohort…”
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Are infections associated with cognitive decline and neuroimaging outcomes? A historical cohort study using data from the UK Biobank study linked to electronic health records by Muzambi, Rutendo, Bhaskaran, Krishnan, Rentsch, Christopher T., Smeeth, Liam, Brayne, Carol, Garfield, Victoria, Williams, Dylan M., Chaturvedi, Nish, Warren-Gash, Charlotte

“…While there is growing evidence of associations between infections and dementia risk, associations with cognitive impairment and potential structural…”
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Impact of linkage quality on inferences drawn from analyses using data with high rates of linkage errors in rural Tanzania by Rentsch, Christopher T, Harron, Katie, Urassa, Mark, Todd, Jim, Reniers, Georges, Zaba, Basia

“…Studies based on high-quality linked data in developed countries show that even minor linkage errors, which occur when records of two different individuals are…”
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Pharmacogenomics driven decision support prototype with machine learning: A framework for improving patient care by Kidwai-Khan, Farah, Rentsch, Christopher T., Pulk, Rebecca, Alcorn, Charles, Brandt, Cynthia A., Justice, Amy C.

“…IntroductionA growing number of healthcare providers make complex treatment decisions guided by electronic health record (EHR) software interfaces. Many…”
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Sustained virological response after treatment with direct antiviral agents in individuals with HIV and hepatitis C co-infection by Lodi, Sara, Klein, Marina, Rauch, Andri, Epstein, Rachel, Wittkop, Linda, Logan, Roger, Rentsch, Christopher T, Justice, Amy C, Touloumi, Giota, Berenguer, Juan, Jarrin, Inma, Egger, Matthias, Puoti, Massimo, D'Arminio Monforte, Antonella, Gill, John, Salmon Ceron, Dominique, van Sighem, Ard, Linas, Benjamin, van der Valk, Marc, Hernán, Miguel A

“…Randomized trials and observational studies have consistently reported rates of sustained virological response (SVR), equivalent to hepatitis C virus (HCV)…”
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Incident dementia risk among patients with type 2 diabetes receiving metformin versus alternative oral glucose-lowering therapy: an observational cohort study using UK primary healthcare records by Doran, William, Tunnicliffe, Louis, Muzambi, Rutendo, Rentsch, Christopher T, Bhaskaran, Krishnan, Smeeth, Liam, Brayne, Carol, Williams, Dylan M, Chaturvedi, Nish, Eastwood, Sophie V, Dunachie, Susanna J, Mathur, Rohini, Warren-Gash, Charlotte

“…Introduction4.2 million individuals in the UK have type 2 diabetes, a known risk factor for dementia and mild cognitive impairment (MCI). Diabetes treatment…”
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Risk of 16 cancers across the full glycemic spectrum: a population-based cohort study using the UK Biobank by Rentsch, Christopher T, Farmer, Ruth E, Eastwood, Sophie V, Mathur, Rohini, Garfield, Victoria, Farmaki, Aliki-Eleni, Bhaskaran, Krishnan, Chaturvedi, Nish, Smeeth, Liam

“…IntroductionDiabetes is observed to increase cancer risk, leading to hypothesized direct effects of either hyperglycemia or medication. We investigated…”
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