Search Results - "Rens, Elisabeth G"
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From energy to cellular forces in the Cellular Potts Model: An algorithmic approach
Published in PLoS computational biology (01-12-2019)“…Single and collective cell dynamics, cell shape changes, and cell migration can be conveniently represented by the Cellular Potts Model, a computational…”
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Cellular Potts modeling of complex multicellular behaviors in tissue morphogenesis
Published in Development, growth & differentiation (01-06-2017)“…Mathematical modeling is an essential approach for the understanding of complex multicellular behaviors in tissue morphogenesis. Here, we review the cellular…”
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3
Mechanical cell-matrix feedback explains pairwise and collective endothelial cell behavior in vitro
Published in PLoS computational biology (01-08-2014)“…In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells during vasculogenesis and angiogenesis…”
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4
Cell Shape and Durotaxis Explained from Cell-Extracellular Matrix Forces and Focal Adhesion Dynamics
Published in iScience (25-09-2020)“…Many cells are small and rounded on soft extracellular matrices (ECM), elongated on stiffer ECMs, and flattened on hard ECMs. Cells also migrate up stiffness…”
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Cell Contractility Facilitates Alignment of Cells and Tissues to Static Uniaxial Stretch
Published in Biophysical journal (28-02-2017)“…During animal development and homeostasis, the structure of tissues, including muscles, blood vessels, and connective tissues, adapts to mechanical strains in…”
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6
Nodal Signaling Range Is Regulated by Proprotein Convertase-Mediated Maturation
Published in Developmental cell (09-03-2015)“…Tissue patterning is established by extracellular growth factors or morphogens. Although different theoretical models explaining specific patterns have been…”
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Cellular Tango: how extracellular matrix adhesion choreographs Rac-Rho signaling and cell movement
Published in Physical biology (01-11-2021)“…The small GTPases Rac and Rho are known to regulate eukaryotic cell shape, promoting front protrusion (Rac) or rear retraction (Rho) of the cell edge. Such…”
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Spots, stripes, and spiral waves in models for static and motile cells: GTPase patterns in cells
Published in Journal of mathematical biology (04-03-2021)“…The polarization and motility of eukaryotic cells depends on assembly and contraction of the actin cytoskeleton and its regulation by proteins called GTPases…”
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Symmetry and fluctuation of cell movements in neural crest-derived facial mesenchyme
Published in Development (Cambridge) (01-05-2021)“…In the face, symmetry is established when bilateral streams of neural crest cells leave the neural tube at the same time, follow identical migration routes and…”
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10
Spots, stripes, and spiral waves in models for static and motile cells
Published in Journal of mathematical biology (01-03-2021)“…The polarization and motility of eukaryotic cells depends on assembly and contraction of the actin cytoskeleton and its regulation by proteins called GTPases…”
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11
Autocrine inhibition of cell motility can drive epithelial branching morphogenesis in the absence of growth
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (14-09-2020)“…Epithelial branching morphogenesis drives the development of organs such as the lung, salivary gland, kidney and the mammary gland. It involves cell…”
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12
Association with pathogenic bacteria affects life‐history traits and population growth in Caenorhabditis elegans
Published in Ecology and evolution (01-04-2015)“…Determining the relationship between individual life‐history traits and population dynamics is an essential step to understand and predict natural selection…”
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13
Mechanical Cell-Matrix Feedback Explains Pairwise and Collective Endothelial Cell Behavior In Vitro: e1003774
Published in PLoS computational biology (01-08-2014)“…In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells during vasculogenesis and angiogenesis…”
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14
Cellular tango: How extracellular matrix adhesion choreographs Rac-Rho signaling and cell movement
Published 19-04-2021“…The small GTPases Rac and Rho are known to regulate eukaryotic cell shape, promoting front protrusion (Rac) or rear retraction (Rho) of the cell edge. Such…”
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15
Cell Shape and Durotaxis Follow from Mechanical Cell-Substrate Reciprocity and Focal Adhesion Dynamics: A Unifying Mathematical Model
Published 21-06-2019“…Many animal cells change their shape depending on the stiffness of the substrate on which they are cultured: they assume small, rounded shapes in soft ECMs,…”
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16
Spots, strips, and spiral waves in models for static and motile cells
Published 23-09-2019“…J. Math. Biol. 82, 28 (2021) The polarization and motility of eukaryotic cells depends on assembly and contraction of the actin cytoskeleton and its regulation…”
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17
Cell contractility facilitates alignment of cells and tissues to static uniaxial stretch
Published 03-03-2017“…Biophysical Journal 112 (4): 755-766 (2017) During animal development and homeostasis, the structure of tissues, including muscles, blood vessels and…”
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18
Mechanical cell-matrix feedback explains pairwise and collective endothelial cell behavior in vitro
Published 04-07-2014“…PLoS Comput Biol 10(8): e1003774, 2014 In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells…”
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