Search Results - "Renner, Lauren M"

Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates by McGill, Trevor J, Stoddard, Jonathan, Renner, Lauren M, Messaoudi, Ilhem, Bharti, Kapil, Mitalipov, Shoukhrat, Lauer, Andreas, Wilson, David J, Neuringer, Martha

“…To characterize the intraocular immune response following transplantation of iPS-derived allogeneic RPE cells into the subretinal space of…”
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Elevated Fundus Autofluorescence in Monkeys Deficient in Lutein, Zeaxanthin, and Omega-3 Fatty Acids by McGill, Trevor J, Renner, Lauren M, Neuringer, Martha

“…We quantified fundus autofluorescence (FAF) in the nonhuman primate retina as a function of age and diets lacking lutein and zeaxanthin (L/Z) and omega-3 fatty…”
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SUBRETINAL CELL-BASED THERAPY: An Analysis of Surgical Variables to Increase Cell Survival by Wilson, David J, Neuringer, Martha, Stoddard, Jonathan, Renner, Lauren M, Bailey, Steven, Lauer, Andreas, McGill, Trevor J

“…To develop a novel surgical approach to provide consistent delivery of cell suspension into the subretinal space without cell leakage into the vitreous. Cell…”
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New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina by Simpson, Elizabeth M, Korecki, Andrea J, Fornes, Oriol, McGill, Trevor J, Cueva-Vargas, Jorge Luis, Agostinone, Jessica, Farkas, Rachelle A, Hickmott, Jack W, Lam, Siu Ling, Mathelier, Anthony, Renner, Lauren M, Stoddard, Jonathan, Zhou, Michelle, Di Polo, Adriana, Neuringer, Martha, Wasserman, Wyeth W

“…Retinal gene therapy is leading the neurological gene therapy field, with 32 ongoing clinical trials of recombinant adeno-associated virus (rAAV)-based…”
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Development of a translatable gene augmentation therapy for CNGB1-retinitis pigmentosa by Occelli, Laurence M., Zobel, Lena, Stoddard, Jonathan, Wagner, Johanna, Pasmanter, Nathaniel, Querubin, Janice, Renner, Lauren M., Reynaga, Rene, Winkler, Paige A., Sun, Kelian, Marinho, Luis Felipe L.P., O’Riordan, Catherine R., Frederick, Amy, Lauer, Andreas, Tsang, Stephen H., Hauswirth, William W., McGill, Trevor J., Neuringer, Martha, Michalakis, Stylianos, Petersen-Jones, Simon M.

“…In this study, we investigate a gene augmentation therapy candidate for the treatment of retinitis pigmentosa (RP) due to cyclic nucleotide-gated channel beta…”
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Cell Transplantation for Retinal Degeneration: Transition from Rodent to Nonhuman Primate Models by McGill, Trevor J, Wilson, David J, Stoddard, Jonathan, Renner, Lauren M, Neuringer, Martha

“…Transplantation of potentially therapeutic cells into the subretinal space is a promising prospective therapy for the treatment of retinal degenerative…”
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Genetic variants in melanogenesis proteins TYRP1 and TYR are associated with the golden rhesus macaque phenotype by Peterson, Samuel M, Watowich, Marina M, Renner, Lauren M, Martin, Samantha, Offenberg, Emma, Lea, Amanda, Montague, Michael J, Higham, James P, Snyder-Mackler, Noah, Neuringer, Martha, Ferguson, Betsy

“…Abstract Nonhuman primates (NHPs) are vital translational research models due to their high genetic, physiological, and anatomical homology with humans. The…”
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A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy by Steinbach, Rosemary J, Haese, Nicole N, Smith, Jessica L, Colgin, Lois M A, MacAllister, Rhonda P, Greene, Justin M, Parkins, Christopher J, Kempton, J Beth, Porsov, Edward, Wang, Xiaojie, Renner, Lauren M, McGill, Trevor J, Dozier, Brandy L, Kreklywich, Craig N, Andoh, Takeshi F, Grafe, Marjorie R, Pecoraro, Heidi L, Hodge, Travis, Friedman, Robert M, Houser, Lisa A, Morgan, Terry K, Stenzel, Peter, Lindner, Jonathan R, Schelonka, Robert L, Sacha, Jonah B, Roberts, Victoria H J, Neuringer, Martha, Brigande, John V, Kroenke, Christopher D, Frias, Antonio E, Lewis, Anne D, Kelleher, Meredith A, Hirsch, Alec J, Streblow, Daniel Neal

“…Zika virus infection during pregnancy is associated with miscarriage and with a broad spectrum of fetal and neonatal developmental abnormalities collectively…”
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