Search Results - "Renne, Ulla"
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Lifelong obesity in a polygenic mouse model prevents age- and diet-induced glucose intolerance- obesity is no road to late-onset diabetes in mice
Published in PloS one (13-11-2013)“…Visceral obesity holds a central position in the concept of the metabolic syndrome characterized by glucose intolerance in humans. However, until now it is…”
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High-fat diets rich in ω-3 or ω-6 polyunsaturated fatty acids have distinct effects on lipid profiles and lipid peroxidation in mice selected for either high body weight or leanness
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-05-2013)“…Abstract Objective The aim of the study is to determine the response of muscle lipid peroxidation and the fatty-acid profile of three groups of mice—high body…”
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3
Dynamics of Fat Mass in DUhTP Mice Selected for Running Performance - Fat Mobilization in a Walk
Published in Obesity facts (01-01-2015)“…Objective: Reduction of body fat can be achieved by dietary programs and/or aerobic exercise training. More convenient methods to rid the body of excess fat…”
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4
Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice
Published in PloS one (29-06-2012)“…We have investigated molecular mechanisms for muscle mass accretion in a non-inbred mouse model (DU6P mice) characterized by extreme muscle mass. This extreme…”
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Metabolic responses to high-fat diets rich in n-3 or n-6 long-chain polyunsaturated fatty acids in mice selected for either high body weight or leanness explain different health outcomes
Published in Nutrition & metabolism (11-08-2011)“…Increasing evidence suggests that diets high in polyunsaturated fatty acids (PUFA) confer health benefits by improving insulin sensitivity and lipid metabolism…”
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High-protein diet in lactation leads to a sudden infant death-like syndrome in mice
Published in PloS one (09-03-2011)“…It is well accepted that reduced foetal growth and development resulting from maternal malnutrition are associated with a number of chronic conditions in later…”
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Extrinsic and intrinsic regulation of DOR/TP53INP2 expression in mice: effects of dietary fat content, tissue type and sex in adipose and muscle tissues
Published in Nutrition & metabolism (21-09-2012)“…DOR/TP53INP2 acts both at the chromosomal level as a nuclear co-factor e.g. for the thyroid hormone receptor and at the extrachromosomal level as an organizing…”
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Two high-fertility mouse lines show differences in component fertility traits after long-term selection
Published in Reproduction fertility and development (01-01-2007)“…Two selected high-fertility mouse lines, namely FL1 and FL2, and a non-selected control (Fzt:DU), all derived from the same genetic pool, were analysed as an…”
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9
Relationships between quantitative and reproductive fitness traits in animals
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-07-2005)“…The relationships between quantitative and reproductive fitness traits in animals are of general biological importance for the development of population…”
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10
Quantitative trait loci affecting body weight and fatness from a mouse line selected for extreme high growth
Published in Genetics (Austin) (01-09-1998)“…Quantitative trait loci (QTL) influencing body weight were mapped by linkage analysis in crosses between a high body weight selected line (DU6) and a control…”
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QTLs for pre- and postweaning body weight and body composition in selected mice
Published in Mammalian genome (01-08-2004)“…In an intercross between the high-body-weight-selected mouse line NMRI8 and the inbred line DBA/2, we analyzed genetic effects on growth during the suckling…”
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Phenotypic characterisation of extreme growth-selected mouse lines: An important prerequisite for future QTL analysis
Published in Open life sciences (01-09-2006)Get full text
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13
Increased fat mass, decreased myofiber size, and a shift to glycolytic muscle metabolism in adolescent male transgenic mice overexpressing IGFBP-2
Published in American journal of physiology: endocrinology and metabolism (01-08-2010)“…To elucidate the functional role of insulin-like growth factor (IGF)-binding protein-2 (IGFBP-2) for in vivo skeletal muscle growth and function, skeletal…”
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14
Metabolic Adaptations in the Liver of Born Long-Distance Running Mice
Published in Medicine and science in sports and exercise (01-05-2013)“…Long-distance runners have increased needs of energy supply. To unravel genetically based mechanisms required for efficient energy supply, we have analyzed…”
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High-fat diets rich in [omega]-3 or [omega]-6 polyunsaturated fatty acids have distinct effects on lipid profiles and lipid peroxidation in mice selected for either high body weight or leanness
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-05-2013)“…Objective The aim of the study is to determine the response of muscle lipid peroxidation and the fatty-acid profile of three groups of mice--high body weight…”
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Single QTL Effects, Epistasis, and Pleiotropy Account for Two-thirds of the Phenotypic F2 Variance of Growth and Obesity in DU6i x DBA/2 Mice
Published in Genome research (01-12-2000)“…Genes influencing body weight and composition and serum concentrations of leptin, insulin, and insulin-like growth factor I (IGF-I) in nonfasting animals were…”
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Chromosome-Wise Dissection of the Genome of the Extremely Big Mouse Line DU6i
Published in Genetics (Austin) (01-01-2006)“…The extreme high-body-weight-selected mouse line DU6i is a polygenic model for growth research, harboring many small-effect QTL. We dissected the genome of…”
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Mice long-term selected for high body mass are more susceptible to body fat deposition in response to a high fat diet due to insufficient increase in heat production
Published in Archiv für Tierzucht (10-10-2012)“…Using a mouse model long-term selected for high body mass (DU6i), we investigated if their higher degree of body fat as compared to unselected controls (DUKsi)…”
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Genetic control of lipids in the mouse cross DU6i × DBA/2
Published in Mammalian genome (01-11-2007)“…An F^sub 2^ pedigree based on the mouse lines DU6i and DBA/2 with extremely different growth and obesity characteristics was generated to search for QTLs…”
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Genetic control of lipids in the mouse cross DU6i x DBA/2
Published in Mammalian genome (01-11-2007)“…An F₂ pedigree based on the mouse lines DU6i and DBA/2 with extremely different growth and obesity characteristics was generated to search for QTLs affecting…”
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