Search Results - "Renn, Dominik"
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A systematic analysis of affinity tags in the haloarchaeal expression system, Haloferax volcanii for protein purification
Published in Frontiers in microbiology (30-05-2024)“…Extremophilic proteins are valuable in various fields, but their expression can be challenging in traditional hosts like due to misfolding and aggregation. (…”
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Bioprospecting of Novel Extremozymes From Prokaryotes-The Advent of Culture-Independent Methods
Published in Frontiers in microbiology (10-02-2021)“…Extremophiles are remarkable organisms that thrive in the harshest environments on Earth, such as hydrothermal vents, hypersaline lakes and pools, alkaline…”
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Bioengineering of air-filled protein nanoparticles by genetic and chemical functionalization
Published in Journal of nanobiotechnology (25-03-2023)“…Various bacteria and archaea, including halophilic archaeon Halobacterium sp. NRC-1 produce gas vesicle nanoparticles (GVNPs), a unique class of stable,…”
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Novel Enzymes From the Red Sea Brine Pools: Current State and Potential
Published in Frontiers in microbiology (27-10-2021)“…The Red Sea is a marine environment with unique chemical characteristics and physical topographies. Among the various habitats offered by the Red Sea, the…”
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Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase
Published in Frontiers in microbiology (28-04-2020)“…Environments previously thought to be uninhabitable offer a tremendous wealth of unexplored microorganisms and enzymes. In this paper, we present the discovery…”
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Advances in One-Pot Chiral Amine Synthesis Enabled by Amine Transaminase Cascades: Pushing the Boundaries of Complexity
Published in ACS catalysis (21-04-2023)“…Amine transaminases constitute an important class of enzymes for the synthesis of chiral amines, which are commonly used as building blocks in pharmaceutical…”
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One-Pot Chemoenzymatic Conversion of Alkynes to Chiral Amines
Published in ACS catalysis (15-10-2021)“…A one-pot chemoenzymatic sequential cascade for the synthesis of chiral amines from alkynes was developed. In this integrated approach, just ppm amounts of…”
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Engineering a Polyspecific Pyrrolysyl-tRNA Synthetase by a High Throughput FACS Screen
Published in Scientific reports (19-08-2019)“…The Pyrrolysyl-tRNA synthetase (PylRS) and its cognate tRNA Pyl are extensively used to add non-canonical amino acids (ncAAs) to the genetic code of bacterial…”
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Interactions of Catalytic Enzymes with n‑Type Polymers for High-Performance Metabolite Sensors
Published in ACS applied materials & interfaces (22-02-2023)“…The tight regulation of the glucose concentration in the body is crucial for balanced physiological function. We developed an electrochemical transistor…”
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Robust and Versatile Host Protein for the Design and Evaluation of Artificial Metal Centers
Published in ACS catalysis (06-12-2019)“…Artificial metalloenzymes (ArMs) have high potential in biotechnological applications as they combine the versatility of transition-metal catalysis with the…”
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Air-loaded Gas Vesicle Nanoparticles Promote Cell Growth in Three-dimensional Bioprinted Tissue Constructs
Published in International journal of bioprinting (01-01-2022)“…Three-dimensional (3D) bioprinting has emerged as a promising method for the engineering of tissues and organs. Still, it faces challenges in its widespread…”
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