Search Results - "Renkema, H."

Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE2 biosynthesis by sonlicromanol’s metabolite KH176m by Jiang, X., Renkema, H., Pennings, B., Pecheritsyna, S., Schoeman, J. C., Hankemeier, T., Smeitink, J., Beyrath, J.

“…Increased prostaglandin E2 (PGE 2 ) levels were detected in mitochondrial disease patient cells harboring nuclear gene mutations in structural subunits of…”
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Mutated PET117 causes complex IV deficiency and is associated with neurodevelopmental regression and medulla oblongata lesions by Renkema, G. H., Visser, G., Baertling, F., Wintjes, L. T., Wolters, V. M., van Montfrans, J., de Kort, G. A. P., Nikkels, P. G. J., van Hasselt, P. M., van der Crabben, S. N., Rodenburg, R. J. T.

“…The genetic basis of the many progressive, multi systemic, mitochondrial diseases that cause a lack of cellular ATP production is heterogeneous, with defects…”
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UP-2.063: Conceiving a Child After Vasovasostomy: Live Birth Rates by Renkema, H, Schroeder, R, De Kemp, V, Kastrop, P, Lock, T

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Cyclic AMP-dependent Protein Kinase Phosphorylates Merlin at Serine 518 Independently of p21-activated Kinase and Promotes Merlin-Ezrin Heterodimerization by Alfthan, Kaija, Heiska, Leena, Grönholm, Mikaela, Renkema, G Herma, Carpén, Olli

“…Mutations in the NF2 tumor suppressor gene encoding merlin induce the development of tumors of the nervous system. Merlin is highly homologous to the ERM ( e…”
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Strong Induction of Members of the Chitinase Family of Proteins in Atherosclerosis: Chitotriosidase and Human Cartilage gp-39 Expressed in Lesion Macrophages by Boot, Rolf G, van Achterberg, Tanja A.E, van Aken, Benien E, Renkema, G. Herma, Jacobs, Michael J.H.M, Aerts, Johannes M.F.G, de Vries, Carlie J.M

“…Atherosclerosis is initiated by the infiltration of monocytes into the subendothelial space of the vessel wall and subsequent lipid accumulation of the…”
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Human Immunodeficiency Virus Type 1 Nef Selectively Associates with a Catalytically Active Subpopulation of p21-Activated Kinase 2 (PAK2) Independently of PAK2 Binding to Nck or β-PIX by Renkema, G H, Manninen, A, Saksela, K

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The human chitotriosidase gene. Nature of inherited enzyme deficiency by Boot, R G, Renkema, G H, Verhoek, M, Strijland, A, Bliek, J, de Meulemeester, T M, Mannens, M M, Aerts, J M

“…The human chitinase, named chitotriosidase, is a member of family 18 of glycosylhydrolases. Following the cloning of the chitotriosidase cDNA (Boot, R. G.,…”
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Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase by Aguilera, Begoña, Ghauharali-van der Vlugt, Karen, Helmond, Mariette T J, Out, Jos M M, Donker-Koopman, Wilma E, Groener, Johanna E M, Boot, Rolf G, Renkema, G Herma, van der Marel, Gijs A, van Boom, Jacques H, Overkleeft, Hermen S, Aerts, Johannes M F G

“…Chitotriosidase is a chitinase that is massively expressed by lipid-laden tissue macrophages in man. Its enzymatic activity is markedly elevated in serum of…”
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Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE 2 biosynthesis by sonlicromanol's metabolite KH176m by Jiang, X, Renkema, H, Pennings, B, Pecheritsyna, S, Schoeman, J C, Hankemeier, T, Smeitink, J, Beyrath, J

“…Increased prostaglandin E2 (PGE ) levels were detected in mitochondrial disease patient cells harboring nuclear gene mutations in structural subunits of…”
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Host–microflora interaction in Systemic Lupus Erythematosus (SLE): colonization resistance of the indigenous bacteria of the intestinal tract by Apperloo-Renkema, H. Z., Bootsma, H., Mulder, B. I., Kallenberg, C. G., Van Der Waaij, D.

“…Experimental data suggest a role for the microflora in Systemic Lupus Erythematosus (SLE). Anti–ds–DNA antibodies may be pathogenic in SLE by forming immune…”
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Applicability of random primer R143 for determination of Aspergillus fumigatus DNA by Erjavec, Z., Brinker, M., Apperloo-Renkem, H.Z., Arends, J.P., De Vries-Hospers, H.G., Ruiters, M.H.J.

“…The specificity of random primer R143 for Aspergillus fumigatus DNA was determined in order to test its usefulness in establishing the presence of A. fumigatus…”
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Identification of the Nef-associated kinase as p21-activated kinase 2 by Renkema, G.Herma, Manninen, Aki, Mann, Derek A., Harris, Mark, Saksela, Kalle

“…The Nef protein of primate immunodeficiency viruses plays an important role in the pathogenesis of acquired immunodeficiency syndrome (AIDS) [1,2]. The…”
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Determination of colonization resistance of the digestive tract by biotyping of Enterobacteriaceae by Apperloo-Renkema, H. Z., Van der Waaij, B. D., Van der Waaij, D.

“…In studies concerning the effect of antibiotics on faecal microflora, Colonization Resistance is an important parameter. Colonization Resistance correlates…”
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Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin by MURANEN, Taru, GRÖNHOLM, Mikaela, HERMA RENKEMA, G, CARPEN, Olli

“…The neurofibromatosis 2 tumour suppressor merlin/schwannomin is structurally related to the ezrin-radixin-moesin family of proteins, which anchor actin…”
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Activation of NFAT-Dependent Gene Expression by Nef: Conservation among Divergent Nef Alleles, Dependence on SH3 Binding and Membrane Association, and Cooperation with Protein Kinase C-θ by Manninen, A, Huotari, P, Hiipakka, M, Renkema, G H, Saksela, K

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cloning of a cDNA Encoding Chitotriosidase, a Human Chitinase Produced by Macrophages (∗) by Boot, Rolf G., Renkema, G. Herma, Strijland, Anneke, van Zonneveld, Anton Jan, Aerts, Johannes M. F.G.

“…We have recently observed that chitotriosidase, a chitinolytic enzyme, is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher…”
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Synergistic Activation of NFAT by HIV-1 Nef and the Ras/MAPK Pathway by Manninen, Aki, Herma Renkema, G., Saksela, Kalle

“…Nef is a lentiviral protein involved in pathogenesis of AIDS, but its molecular mechanisms of action remain incompletely understood. Here we report a novel…”
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Study of colonization resistance for Enterobacteriaceae in man by experimental contamination and biotyping as well as the possible role of antibodies in the clearance of these bacteria from the intestines by Apperloo-Renkema, H. Z., Van Der Waaij, D.

“…The colonization resistance (CR) of the digestive tract was determined in 10 healthy volunteers by oral contamination with a neomycin resistant Escherichia…”
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Host-microflora interaction in systemic lupus erythematosus (SLE): circulating antibodies to the indigenous bacteria of the intestinal tract by Apperloo-Renkema, H. Z., Bootsma, H., Mulder, B. I., Kallenberg, C. G. M., Van der Waaij, D.

“…Experimental data suggest a role for the microflora in the disease expression of systemic lupus erythematosus (SLE). In active SLE anti-ds-DNA antibodies are…”
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Healthy individuals possess circulating antibodies against their indigenous faecal microflora as well as against allogenous faecal microflora: an immunomorphometrical study by Apperloo-Renkema, H. Z., Jagt, T. G., Tonk, R. H. J, van der Waaij, D.

“…Healthy persons were shown to possess circulating antibodies of both IgA, IgG and IgM isotype directed against the bacteria of their faecal microflora,…”
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