Search Results - "Renes, Ingrid"

The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection by Burger-van Paassen, Nanda, Vincent, Audrey, Puiman, Patrycja J, van der Sluis, Maria, Bouma, Janneke, Boehm, Günther, van Goudoever, Johannes B, van Seuningen, Isabelle, Renes, Ingrid B

“…SCFAs (short-chain fatty acids), fermentation products of bacteria, influence epithelial-specific gene expression. We hypothesize that SCFAs affect…”
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Targeting the gut microbiota to influence brain development and function in early life by Wang, Shugui, Harvey, Louise, Martin, Rocio, van der Beek, Eline M., Knol, Jan, Cryan, John F., Renes, Ingrid B.

“…•There are developmental parallels between the brain and the gut during early life.•Three mechanisms are proposed as to how gut microbiota may communicate with…”
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Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic Protection by Van der Sluis, Maria, De Koning, Barbara A.E., De Bruijn, Adrianus C.J.M., Velcich, Anna, Meijerink, Jules P.P., Van Goudoever, Johannes B., Büller, Hans A., Dekker, Jan, Van Seuningen, Isabelle, Renes, Ingrid B., Einerhand, Alexandra W.C.

“…Background & Aims: Expression of mucin MUC2, the structural component of the colonic mucus layer, is lowered in inflammatory bowel disease. Our aim was to…”
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A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small Intestine by Roodsant, Thomas, Navis, Marit, Aknouch, Ikrame, Renes, Ingrid B, van Elburg, Ruurd M, Pajkrt, Dasja, Wolthers, Katja C, Schultsz, Constance, van der Ark, Kees C H, Sridhar, Adithya, Muncan, Vanesa

“…Gut organoids are stem cell derived 3D models of the intestinal epithelium that are useful for studying interactions between enteric pathogens and their host…”
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Mouse fetal intestinal organoids: new model to study epithelial maturation from suckling to weaning by Navis, Marit, Martins Garcia, Tânia, Renes, Ingrid B, Vermeulen, Jacqueline LM, Meisner, Sander, Wildenberg, Manon E, van den Brink, Gijs R, van Elburg, Ruurd M, Muncan, Vanesa

“…During the suckling‐to‐weaning transition, the intestinal epithelium matures, allowing digestion of solid food. Transplantation experiments with rodent fetal…”
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Intervention strategies for cesarean section–induced alterations in the microbiota-gut-brain axis by Moya-Pérez, Angela, Luczynski, Pauline, Renes, Ingrid B., Wang, Shugui, Borre, Yuliya, Anthony Ryan, C., Knol, Jan, Stanton, Catherine, Dinan, Timothy G., Cryan, John F.

“…Microbial colonization of the gastrointestinal tract is an essential process that modulates host physiology and immunity. Recently, researchers have begun to…”
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Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse by Morais, Livia H., Golubeva, Anna V., Moloney, Gerard M., Moya-Pérez, Angela, Ventura-Silva, Ana Paula, Arboleya, Silvia, Bastiaanssen, Thomaz F.S., O’Sullivan, Orla, Rea, Kieran, Borre, Yuliya, Scott, Karen A., Patterson, Elaine, Cherry, Paul, Stilling, Roman, Hoban, Alan E., El Aidy, Sahar, Sequeira, Ana M., Beers, Sasja, Moloney, Rachel D., Renes, Ingrid B., Wang, Shugui, Knol, Jan, Ross, R. Paul, O’Toole, Paul W., Cotter, Paul D., Stanton, Catherine, Dinan, Timothy G., Cryan, John F.

“…Birth by Caesarean (C)-section impacts early gut microbiota colonization and is associated with an increased risk of developing immune and metabolic disorders…”
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Gastrointestinal Protein Hydrolysis Kinetics: Opportunities for Further Infant Formula Improvement by Abrahamse, Evan, Thomassen, Gabriël G M, Renes, Ingrid B, Wierenga, Peter A, Hettinga, Kasper A

“…The postprandial plasma essential amino acid (AA) peak concentrations of infant formula (IF) are higher than those of human milk (HM) in infants. In addition,…”
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Association between duration of intravenous antibiotic administration and early-life microbiota development in late-preterm infants by Zwittink, Romy D, Renes, Ingrid B, van Lingen, Richard A, van Zoeren-Grobben, Diny, Konstanti, Prokopis, Norbruis, Obbe F, Martin, Rocio, Groot Jebbink, Liesbeth J M, Knol, Jan, Belzer, Clara

“…Antibiotic treatment is common practice in the neonatal ward for the prevention and treatment of sepsis, which is one of the leading causes of mortality and…”
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Delayed growth, motor function and learning in preterm pigs during early postnatal life by Andersen, Anders D, Sangild, Per T, Munch, Sara L, van der Beek, Eline M, Renes, Ingrid B, Ginneken, Chris van, Greisen, Gorm O, Thymann, Thomas

“…Preterm birth interrupts normal fetal growth with consequences for postnatal growth and organ development. In preterm infants, many physiological deficits…”
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Maturation of the preterm gastrointestinal tract can be defined by host and microbial markers for digestion and barrier defense by Henderickx, Jannie G. E., Zwittink, Romy D., Renes, Ingrid B., van Lingen, Richard A., van Zoeren-Grobben, Diny, Jebbink, Liesbeth J. Groot, Boeren, Sjef, van Elburg, Ruurd M., Knol, Jan, Belzer, Clara

“…Functionality of the gastrointestinal tract is essential for growth and development of newborns. Preterm infants have an immature gastrointestinal tract, which…”
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Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3β, Reg3γ and angiogenin-4 by Burger-van Paassen, Nanda, Loonen, Linda M P, Witte-Bouma, Janneke, Korteland-van Male, Anita M, de Bruijn, Adrianus C J M, van der Sluis, Maria, Lu, Peng, Van Goudoever, Johannes B, Wells, Jerry M, Dekker, Jan, Van Seuningen, Isabelle, Renes, Ingrid B

“…Mucin Muc2 is the structural component of the intestinal mucus layer. Absence of Muc2 leads to loss of this layer allowing direct bacterial-epithelial…”
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Dynamics of the bacterial gut microbiota in preterm and term infants after intravenous amoxicillin/ceftazidime treatment by Zwittink, Romy D, van Zoeren-Grobben, Diny, Renes, Ingrid B, van Lingen, Richard A, Norbruis, Obbe F, Martin, Rocio, Groot Jebbink, Liesbeth J, Knol, Jan, Belzer, Clara

“…It is important to understand the consequences of pre-emptive antibiotic treatment in neonates, as disturbances in microbiota development during this key…”
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Ischaemia-induced mucus barrier loss and bacterial penetration are rapidly counteracted by increased goblet cell secretory activity in human and rat colon by Grootjans, Joep, Hundscheid, Inca H R, Lenaerts, Kaatje, Boonen, Bas, Renes, Ingrid B, Verheyen, Fons K, Dejong, Cornelis H, von Meyenfeldt, Maarten F, Beets, Geerard L, Buurman, Wim A

“…Colonic ischaemia is frequently observed in clinical practice. This study provides a novel insight into the pathophysiology of colon ischaemia/reperfusion (IR)…”
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Beneficial Effect of Mildly Pasteurized Whey Protein on Intestinal Integrity and Innate Defense in Preterm and Near-Term Piglets by Navis, Marit, Muncan, Vanesa, Sangild, Per Torp, Møller Willumsen, Line, Koelink, Pim J, Wildenberg, Manon E, Abrahamse, Evan, Thymann, Thomas, van Elburg, Ruurd M, Renes, Ingrid B

“…The human digestive tract is structurally mature at birth, yet maturation of gut functions such as digestion and mucosal barrier continues for the next 1-2…”
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Mildly Pasteurized Whey Protein Promotes Gut Tolerance in Immature Piglets Compared with Extensively Heated Whey Protein by Navis, Marit, Schwebel, Lauriane, Soendergaard Kappel, Susanne, Muncan, Vanesa, Sangild, Per Torp, Abrahamse, Evan, Aunsholt, Lise, Thymann, Thomas, van Elburg, Ruurd M, Renes, Ingrid B

“…Human milk is the optimal diet for infant development, but infant milk formula (IMF) must be available as an alternative. To develop high-quality IMF, bovine…”
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Endoplasmic reticulum stress, unfolded protein response and altered T cell differentiation in necrotizing enterocolitis by Lu, Peng, Struijs, Marie-Chantal, Mei, Jiaping, Witte-Bouma, Janneke, Korteland-van Male, Anita M, de Bruijn, Adrianus C J M, van Goudoever, Johannes B, Renes, Ingrid B

“…Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) play important roles in chronic intestinal inflammation. Necrotizing…”
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Synbiotics Combined with Glutamine Stimulate Brain Development and the Immune System in Preterm Pigs by Andersen, Anders D, Nguyen, Duc Ninh, Langhorn, Louise, Renes, Ingrid B, van Elburg, Ruurd M, Hartog, Anita, Tims, Sebastian, van de Looij, Yohan, Sangild, Per T, Thymann, Thomas

“…Preterm infants are born with an immature gut, brain, and immune system, predisposing them to short- and long-term complications. We hypothesized that a milk…”
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Metaproteomics reveals functional differences in intestinal microbiota development of preterm infants by Zwittink, Romy D., van Zoeren-Grobben, Diny, Martin, Rocio, van Lingen, Richard A., Groot Jebbink, Liesbeth J., Boeren, Sjef, Renes, Ingrid B., van Elburg, Ruurd M., Belzer, Clara, Knol, Jan

“…Objective: Development of the gastrointestinal tract and immune system can be modulated by the gut microbiota. Establishment of the intestinal microbiota, in…”
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High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice by Lu, Peng, Bar-Yoseph, Fabiana, Levi, Liora, Lifshitz, Yael, Witte-Bouma, Janneke, de Bruijn, Adrianus C J M, Korteland-van Male, Anita M, van Goudoever, Johannes B, Renes, Ingrid B

“…Palmitic-acid esterified to the sn-1,3 positions of the glycerol backbone (alpha, alpha'-palmitate), the predominant palmitate conformation in regular infant…”
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