Search Results - "Rene Koopman"
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Time-resolved phosphoproteome and proteome analysis reveals kinase signaling on master transcription factors during myogenesis
Published in iScience (17-06-2022)“…Myogenesis is governed by signaling networks that are tightly regulated in a time-dependent manner. Although different protein kinases have been identified,…”
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Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity
Published in Molecular metabolism (Germany) (01-03-2021)“…Preferential damage to fast, glycolytic myofibers is common in many muscle-wasting diseases, including Duchenne muscular dystrophy (DMD). Promoting an…”
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Distinct roles for dietary protein and amino acids in health and disease
Published in Current opinion in clinical nutrition and metabolic care (01-01-2021)Get full text
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Aging Is Accompanied by a Blunted Muscle Protein Synthetic Response to Protein Ingestion
Published in PloS one (04-11-2015)“…Progressive loss of skeletal muscle mass with aging (sarcopenia) forms a global health concern. It has been suggested that an impaired capacity to increase…”
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Dietary protein and exercise training in ageing
Published in Proceedings of the Nutrition Society (01-02-2011)“…Ageing is accompanied by a progressive loss of skeletal muscle mass and strength, leading to the loss of functional capacity and an increased risk for…”
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Dietary meat and protection against sarcopenia
Published in Meat science (01-10-2018)“…Sarcopenia describes the age-related loss of skeletal muscle mass and associated muscle weakness. Sarcopenia is a major global health problem given that the…”
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Assessment of impairment and activity limitations in the critically ill: a systematic review of measurement instruments and their clinimetric properties
Published in Intensive care medicine (01-05-2015)“…Purpose To identify measures used to evaluate the broad constructs of functional impairment and limitations in the critically ill across the continuum of…”
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A Single Session of Resistance Exercise Induces Oxidative Damage in Untrained Men
Published in Medicine and science in sports and exercise (01-12-2007)“…During exercise, the production of reactive oxygen and nitrogen species significantly increases. The aim of the present study was to investigate the effects of…”
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Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function
Published in Journal of critical care (01-10-2015)“…Abstract Purpose This study aimed to (1) document patterns of quadriceps muscle wasting in the first 10 days of admission and (2) determine the relationship…”
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Aging, exercise, and muscle protein metabolism
Published in Journal of applied physiology (1985) (01-06-2009)“…1 Department of Human Movement Sciences, Nutrition, and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands; and 2…”
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Age-Related Changes in Skeletal Muscle Iron Homeostasis
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (26-01-2023)“…Sarcopenia is an age-related condition of slow, progressive loss of muscle mass and strength, which contributes to frailty, increased risk of hospitalization…”
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Spatiotemporal Mapping Reveals Regional Gastrointestinal Dysfunction in mdx Dystrophic Mice Ameliorated by Oral L-arginine Supplementation
Published in Journal of neurogastroenterology and motility (31-01-2020)“…Background/Aims Patients with Duchenne muscular dystrophy exhibit significant, ongoing impairments in gastrointestinal (GI) function likely resulting from…”
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Exercising before protein intake allows for greater use of dietary protein–derived amino acids for de novo muscle protein synthesis in both young and elderly men
Published in The American journal of clinical nutrition (01-02-2011)“…Background: Sarcopenia seems to be attributed to a blunted muscle protein synthetic response to food intake and exercise. This blunted response could be the…”
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Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia
Published in Clinical nutrition (Edinburgh, Scotland) (01-06-2014)“…Summary Background and aims The non-essential amino acid, glycine, is often considered biologically neutral, but some studies indicate that it could be an…”
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Suicide prevention and management in the SA National Defence Force : a psychological discussion
Published in Scientia militaria : South African journal of military studies (25-05-2012)“…Suicidal behaviour is a challenge for military forces around the world. Suicide can be a reaction in peacekeeping operations or conventional warfare, because…”
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Leucine as a treatment for muscle wasting: A critical review
Published in Clinical nutrition (Edinburgh, Scotland) (01-12-2014)“…Summary Amino acids are potent modulators of protein turnover and skeletal muscle cells are highly sensitive to changes in amino acid availability. During…”
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Symposium 2: Exercise and protein nutrition Dietary protein and exercise training in ageing
Published in Proceedings of the Nutrition Society (01-02-2011)Get full text
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Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly
Published in American journal of physiology: endocrinology and metabolism (01-01-2007)“…Satellite cells (SC) are essential for skeletal muscle growth and repair. Because sarcopenia is associated with type II muscle fiber atrophy, we hypothesized…”
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Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice
Published in Scientific reports (10-09-2019)“…Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids…”
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A metabolic link to skeletal muscle wasting and regeneration
Published in Frontiers in physiology (2014)“…Due to its essential role in movement, insulating the internal organs, generating heat to maintain core body temperature, and acting as a major energy storage…”
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