Search Results - "Ren, Zhenning"

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    Structure and mechanism of human diacylglycerol O-acyltransferase 1 by Wang, Lie, Qian, Hongwu, Nian, Yin, Han, Yimo, Ren, Zhenning, Zhang, Hanzhi, Hu, Liya, Prasad, B. V. Venkataram, Laganowsky, Arthur, Yan, Nieng, Zhou, Ming

    Published in Nature (London) (01-05-2020)
    “…Diacylglycerol O -acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans 1 . DGAT1…”
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    Structural basis of ion transport and inhibition in ferroportin by Pan, Yaping, Ren, Zhenning, Gao, Shuai, Shen, Jiemin, Wang, Lie, Xu, Zhichun, Yu, Ye, Bachina, Preetham, Zhang, Hanzhi, Fan, Xiao, Laganowsky, Arthur, Yan, Nieng, Zhou, Ming

    Published in Nature communications (10-11-2020)
    “…Ferroportin is an iron exporter essential for releasing cellular iron into circulation. Ferroportin is inhibited by a peptide hormone, hepcidin. In humans,…”
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    Mechanism of ligand activation of a eukaryotic cyclic nucleotide−gated channel by Zheng, Xiangdong, Fu, Ziao, Su, Deyuan, Zhang, Yuebin, Li, Minghui, Pan, Yaping, Li, Huan, Li, Shufang, Grassucci, Robert A., Ren, Zhenning, Hu, Zhengshan, Li, Xueming, Zhou, Ming, Li, Guohui, Frank, Joachim, Yang, Jian

    Published in Nature structural & molecular biology (01-07-2020)
    “…Cyclic nucleotide–gated (CNG) channels convert cyclic nucleotide (CN) binding and unbinding into electrical signals in sensory receptors and neurons. The…”
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    Structural basis for inhibition and regulation of a chitin synthase from Candida albicans by Ren, Zhenning, Chhetri, Abhishek, Guan, Ziqiang, Suo, Yang, Yokoyama, Kenichi, Lee, Seok-Yong

    Published in Nature structural & molecular biology (01-07-2022)
    “…Chitin is an essential component of the fungal cell wall. Chitin synthases (Chss) catalyze chitin formation and translocation across the membrane and are…”
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    Extracellular domain of PepT1 interacts with TM1 to facilitate substrate transport by Shen, Jiemin, Hu, Miaohui, Fan, Xiao, Ren, Zhenning, Portioli, Corinne, Yan, Xiuwen, Rong, Mingqiang, Zhou, Ming

    Published in Structure (London) (07-07-2022)
    “…Mammalian peptide transporters, PepT1 and PepT2, mediate uptake of small peptides and are essential for their absorption. PepT also mediates absorption of many…”
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    Insight into the mechanism of H + -coupled nucleobase transport by Weng, Jun, Zhou, Xiaoming, Wiriyasermkul, Pattama, Ren, Zhenning, Chen, Kehan, Gil-Iturbe, Eva, Zhou, Ming, Quick, Matthias

    “…Members of the nucleobase/ascorbic acid transporter (NAT) gene family are found in all kingdoms of life. In mammals, the concentrative uptake of ascorbic acid…”
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    Molecular Simulation and Biochemical Studies Support an Elevator-type Transport Mechanism in EIIC by Lee, Jumin, Ren, Zhenning, Zhou, Ming, Im, Wonpil

    Published in Biophysical journal (06-06-2017)
    “…Enzyme IIC (EIIC) is a membrane-embedded sugar transport protein that is part of the phosphoenolpyruvate-dependent phosphotransferases. Crystal structures of…”
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    The Structure of a Sugar Transporter of the Glucose EIIC Superfamily Provides Insight into the Elevator Mechanism of Membrane Transport by McCoy, Jason G., Ren, Zhenning, Stanevich, Vitali, Lee, Jumin, Mitra, Sharmistha, Levin, Elena J., Poget, Sebastien, Quick, Matthias, Im, Wonpil, Zhou, Ming

    Published in Structure (London) (07-06-2016)
    “…The phosphoenolpyruvate:carbohydrate phosphotransferase systems are found in bacteria, where they play central roles in sugar uptake and regulation of cellular…”
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    Structure of an EIIC sugar transporter trapped in an inward-facing conformation by Ren, Zhenning, Lee, Jumin, Moosa, Mahdi Muhammad, Nian, Yin, Hu, Liya, Xu, Zhichun, McCoy, Jason G., Ferreon, Allan Chris M., Im, Wonpil, Zhou, Ming

    “…The phosphoenolpyruvate-dependent phosphotransferase system (PTS) transports sugar into bacteria and phosphorylates the sugar for metabolic consumption. The…”
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    Controllable Molecule Transport and Release by a Restorable Surface-tethered DNA nanodevice by Wang, Zhaoyin, Xu, Yuanyuan, Wang, Haiyan, Liu, Fengzhen, Ren, Zhenning, Wang, Zhaoxia

    Published in Scientific reports (07-07-2016)
    “…In this paper, we report a novel surface-tethered DNA nanodevice that may present three states and undergo conformational changes under the operation of pH…”
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