Search Results - "Ren, Xuxin"

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    METTL1 promotes hepatocarcinogenesis via m7G tRNA modification‐dependent translation control by Chen, Zhihang, Zhu, Wanjie, Zhu, Shenghua, Sun, Kaiyu, Liao, Junbin, Liu, Haining, Dai, Zihao, Han, Hui, Ren, Xuxin, Yang, Qingxia, Zheng, Siyi, Peng, Baogang, Peng, Sui, Kuang, Ming, Lin, Shuibin

    Published in Clinical and translational medicine (01-12-2021)
    “…Background N7‐methylguanosine (m7G) modification is one of the most common transfer RNA (tRNA) modifications in humans. The precise function and molecular…”
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    Journal Article
  3. 3

    Pretreatment of Grape Seed Proanthocyanidin Extract Exerts Neuroprotective Effect in Murine Model of Neonatal Hypoxic-ischemic Brain Injury by Its Antiapoptotic Property by Tu, Xing, Wang, Mengxia, Liu, Yilin, Zhao, Wenyan, Ren, Xuxin, Li, Yuanjun, Liu, Hongqing, Gu, Ziting, Jia, Hui, Liu, Jing, Li, Guoying, Luo, Li

    Published in Cellular and molecular neurobiology (01-10-2019)
    “…Grape seed proanthocyanidin extract (GSPE), an active component extracted from the grape, has been reported to demonstrate antioxidant, anti-inflammatory,…”
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    Journal Article
  4. 4

    The activation of mTOR signalling modulates DNA methylation by enhancing DNMT1 translation in hepatocellular carcinoma by Chen, Mengke, Fang, Yi, Liang, Meinong, Zhang, Ning, Zhang, Xinyue, Xu, Lixia, Ren, Xuxin, Zhang, Qingfeng, Zhou, Yufeng, Peng, Sui, Yu, Jun, Zeng, Judeng, Li, Xiaoxing

    Published in Journal of translational medicine (23-04-2023)
    “…Both dysregulation of mechanistic target of rapamycin (mTOR) signalling and DNA methylation patterns have been shown to be closely associated with tumor…”
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  5. 5

    Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer by Chen, Zhihang, Zhang, Guopei, Ren, Xiaoxue, Yao, Zhijia, Zhou, Qian, Ren, Xuxin, Chen, Shuling, Xu, Lixia, Sun, Kaiyu, Zeng, Qianwen, Kuang, Ming, Kuang, Dong-Ming, Peng, Sui

    Published in Cancer research (Chicago, Ill.) (01-11-2023)
    “…Abstract The tumor microenvironment is distinctive in primary and secondary liver cancer. B cells represent an important component of immune infiltrates. Here,…”
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    Targeting tumour-intrinsic N 7 -methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy by Liu, Haining, Zeng, Xuezhen, Ren, Xuxin, Zhang, Yifan, Huang, Manling, Tan, Li, Dai, Zihao, Lai, Jiaming, Xie, Wenxuan, Chen, Zebin, Peng, Sui, Xu, Lixia, Chen, Shuling, Shen, Shunli, Kuang, Ming, Lin, Shuibin

    Published in Gut (01-08-2023)
    “…Intrahepatic cholangiocarcinoma (ICC) exhibits very low response rate to immune checkpoint inhibitors (ICIs) and the underlying mechanism is largely unknown…”
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    Journal Article
  9. 9

    METTL5-mediated 18S rRNA m6A modification promotes oncogenic mRNA translation and intrahepatic cholangiocarcinoma progression by Dai, Zihao, Zhu, Wanjie, Hou, Yingdong, Zhang, Xinyue, Ren, Xuxin, Lei, Kai, Liao, Junbin, Liu, Haining, Chen, Zhihang, Peng, Sui, Li, Shaoqiang, Lin, Shuibin, Kuang, Ming

    Published in Molecular therapy (01-11-2023)
    “…Intrahepatic cholangiocarcinoma (ICC) is a deadly cancer with rapid tumor progression. While hyperactive mRNA translation caused by mis-regulated mRNA or tRNA…”
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  10. 10

    Crosstalk between myeloid and B cells shapes the distinct microenvironments of primary and secondary liver cancer by Chen, Zhihang, Zhang, Guopei, Ren, Xiaoxue, Yao, Zhijia, Zhou, Qian, Ren, Xuxin, Chen, Shuling, Xu, Lixia, Sun, Kaiyu, Zeng, Qianwen, Kuang, Ming, Kuang, Dong-Ming, Peng, Sui

    Published in Cancer research (Chicago, Ill.) (23-06-2023)
    “…The tumor microenvironment is distinctive in primary and secondary liver cancer. B cells represent an important component of immune infiltrates. Here, we…”
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    Journal Article
  11. 11

    Intratumoral erythroblastic islands restrain anti-tumor immunity in hepatoblastoma by Wang, Yuanqi, Xiang, Xiao, Chen, Huadong, Zhou, Luyao, Chen, Shuling, Zhang, Guopei, Liu, Xiaofei, Ren, Xuxin, Liu, Juncheng, Kuang, Ming, Jiang, Juan, She, Jinbiao, Zhang, Zhichong, Xue, Ruidong, Jiang, Hong, Wang, Ji, Peng, Sui

    Published in Cell reports. Medicine (16-05-2023)
    “…Erythroblastic islands (EBIs) are the specialized structures for erythropoiesis, but they have never been found functional in tumors. As the most common…”
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  12. 12

    Decreased expression of ubiquilin‑1 following neonatal hypoxia‑ischemic brain injury in mice by Luo, Li, Liu, Yilin, Tu, Xing, Ren, Xuxin, Zhao, Wenyan, Liu, Jing, Zhang, Li, Chen, Weiqiang, Zhang, Pei, Wang, Weicai, Lü, Lanhai, Wang, Mengxia

    Published in Molecular medicine reports (01-06-2019)
    “…Ubiquilin‑1 (Ubqln), a ubiquitin‑like protein, regulates degradation of misfolded proteins and has been reported to have a crucial role in multiple pathologic…”
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  13. 13

    METTL1 promotes hepatocarcinogenesis via m 7 G tRNA modification-dependent translation control by Chen, Zhihang, Zhu, Wanjie, Zhu, Shenghua, Sun, Kaiyu, Liao, Junbin, Liu, Haining, Dai, Zihao, Han, Hui, Ren, Xuxin, Yang, Qingxia, Zheng, Siyi, Peng, Baogang, Peng, Sui, Kuang, Ming, Lin, Shuibin

    Published in Clinical and translational medicine (01-12-2021)
    “…N -methylguanosine (m G) modification is one of the most common transfer RNA (tRNA) modifications in humans. The precise function and molecular mechanism of m…”
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    Journal Article