Search Results - "Ren, Xiubao"

Cancer immunology and immunotherapy by Ren, Xiubao

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Immunosuppressive checkpoint Siglec-15: a vital new piece of the cancer immunotherapy jigsaw puzzle by Ren, Xiubao

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Immunotherapy for hepatocellular carcinoma by Li, Shuzhan, Yang, Fan, Ren, Xiubao

“…Hepatocellular carcinoma (HCC) is the most common type of hepatic malignancies, with poor prognosis. Treatment for HCC are limited, especially for patients…”
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Novel strategies for cancer immunotherapy: counter-immunoediting therapy by Liu, Shaochuan, Sun, Qian, Ren, Xiubao

“…The advent of immunotherapy has made an indelible mark on the field of cancer therapy, especially the application of immune checkpoint inhibitors in clinical…”
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The role of toll-like receptor 4 in tumor microenvironment by Li, Jing, Yang, Fan, Wei, Feng, Ren, Xiubao

“…Tumors are closely related to chronic inflammation, during which there are various changes in inflammatory sites, such as immune cells infiltration,…”
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New Insights into Tumor-Infiltrating B Lymphocytes in Breast Cancer: Clinical Impacts and Regulatory Mechanisms by Shen, Meng, Wang, Jian, Ren, Xiubao

“…Currently, tumor-infiltrating B lymphocytes have been recognized as a new hallmark of breast cancer (BC). The function seems to be controversial, either with…”
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The Clinical Significance of SIRT2 in Malignancies: A Tumor Suppressor or an Oncogene? by Zhang, Lin, Kim, Sungjune, Ren, Xiubao

“…Sirtuin 2 (SIRT2) is a member of the sirtuin protein family. It is a Class III histone deacetylase (HDACs) and predominantly localized to the cytosol. SIRT2…”
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Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting ONECUT2 by Shen, Meng, Dong, Chuan, Ruan, Xianhui, Yan, Wei, Cao, Minghui, Pizzo, Donald, Wu, Xiwei, Yang, Lin, Liu, Liang, Ren, Xiubao, Wang, Shizhen Emily

“…Cancer-secreted, extracellular vesicle (EV)-encapsulated miRNAs enable cancer cells to communicate with each other and with noncancerous cells in tumor…”
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Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis by Fong, Miranda Y., Zhou, Weiying, Liu, Liang, Alontaga, Aileen Y., Chandra, Manasa, Ashby, Jonathan, Chow, Amy, O’Connor, Sean Timothy Francis, Li, Shasha, Chin, Andrew R., Somlo, George, Palomares, Melanie, Li, Zhuo, Tremblay, Jacob R., Tsuyada, Akihiro, Sun, Guoqiang, Reid, Michael A., Wu, Xiwei, Swiderski, Piotr, Ren, Xiubao, Shi, Yanhong, Kong, Mei, Zhong, Wenwan, Chen, Yuan, Wang, Shizhen Emily

“…Reprogrammed glucose metabolism as a result of increased glycolysis and glucose uptake is a hallmark of cancer. Here we show that cancer cells can suppress…”
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Editorial: Endogenous danger signals in cancer immunology and immunotherapy by Ren, Xiubao, Gao, Jinming, Jiang, Jingting

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Myeloid-derived suppressor cells regulate the immunosuppressive functions of PD-1−PD-L1+ Bregs through PD-L1/PI3K/AKT/NF-κB axis in breast cancer by Liu, Min, Wei, Feng, Wang, Jian, Yu, Wenwen, Shen, Meng, Liu, Ting, Zhang, Dong, Wang, Yang, Ren, Xiubao, Sun, Qian

“…Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of myeloid cells that are closely related to tumor immune escape, but the mechanism by which…”
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Exhausted T cells and epigenetic status by Zeng, Ziqing, Wei, Feng, Ren, Xiubao

“…Exhausted T cells are a group of dysfunctional T cells, which are present in chronic infections or tumors. The most significant characteristics of exhausted T…”
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Chromosome Abnormalities: New Insights into Their Clinical Significance in Cancer by Kou, Fan, Wu, Lei, Ren, Xiubao, Yang, Lili

“…Chromosomal abnormalities, consisting of numerical and structural chromosome abnormalities, are a common characteristic of cancer. Numerical chromosome…”
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High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer by Wei, Lijuan, Zhu, Shanshan, Li, Menghui, Li, Fangxuan, Wei, Feng, Liu, Juntian, Ren, Xiubao

“…Indoleamine 2,3-dioxygenase (IDO), which catalyzes the breakdown of the essential amino acid tryptophan into kynurenine, is understood to have a key role in…”
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Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma by WU, YANSHENG, ZHANG, LI, ZHANG, LUN, WANG, YANG, LI, HUI, REN, XIUBAO, WEI, FENG, YU, WENWEN, LIU, TING, WANG, XUDONG, ZHOU, XUAN, YU, JINPU, HAO, XISHAN

“…HOX transcript antisense RNA (HOTAIR), a long intergenic non-coding RNA (lncRNA), functions as a molecular scaffold to link and target the histone modification…”
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Fibroblast activation protein: A potential therapeutic target in cancer by Liu, Rui, Li, Hui, Liu, Liang, Yu, Jinpu, Ren, Xiubao

“…The concept of targeting antigens selectively expressed on the surface of tumor capillary endothelial cells or in tumor stroma has emerged as a promising…”
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The role of phosphoglycerate mutase 1 in tumor aerobic glycolysis and its potential therapeutic implications by Jiang, Xiangli, Sun, Qian, Li, Hui, Li, Kai, Ren, Xiubao

“…A significant characteristic of cancer cell metabolism is the high level of aerobic glycolysis with high glucose consumption and lactate production…”
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CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells by TSUYADA, Akihiro, CHOW, Amy, SHIUAN CHEN, WEIYING ZHOU, YANG YU, WANG, Yuan-Zhong, XIUBAO REN, HUI LI, SCHERLE, Peggy, KUROKI, Yukio, WANG, Shizhen Emily, JUN WU, SOMLO, George, PEIGUO CHU, LOERA, Sofia, LUU, Thehang, XUEJUN LI, Arthur, XIWEI WU, WEI YE

“…Cancer stem cells (CSC) play critical roles in cancer initiation, progression, and therapeutic refractoriness. Although many studies have focused on the genes…”
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Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis by Li, Baihui, Zhang, Bailu, Wang, Xuezhou, Zeng, Ziqing, Huang, Ziqi, Zhang, Lin, Wei, Feng, Ren, Xiubao, Yang, Lili

“…Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) is considered a novel anti-tumor target comparable to programmed cell death 1 ligand 1(PD-L1)…”
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Insights into tertiary lymphoid structures in the solid tumor microenvironment: anti-tumor mechanism, functional regulation, and immunotherapeutic strategies by Zhao, Hua, Wang, Hao, Zhou, Qiuru, Ren, Xiubao

“…Tertiary lymphoid structures (TLSs) are ectopic immune cell aggregations that develop in peripheral tissues in response to a wide range of chronic inflammatory…”
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