Search Results - "Ren, Xingjie"
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Enhanced droplet repellency and jumping condensation on superhydrophobic lubricant-infused surfaces at high subcooling temperatures
Published in Applied physics. A, Materials science & processing (01-12-2023)“…Superhydrophobic surfaces (SHSs) have received significant attention due to their low surface energy, which facilitates droplet dewetting transition and…”
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2
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes
Published in Nature genetics (01-08-2019)“…Mutations in gene regulatory elements have been associated with a wide range of complex neuropsychiatric disorders. However, due to their cell-type specificity…”
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3
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2013)“…The ability to engineer genomes in a specific, systematic, and cost-effective way is critical for functional genomic studies. Recent advances using the…”
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Enhanced Specificity and Efficiency of the CRISPR/Cas9 System with Optimized sgRNA Parameters in Drosophila
Published in Cell reports (Cambridge) (06-11-2014)“…The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies in Drosophila melanogaster. However, single-guide RNA (sgRNA)…”
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5
Phosphatidylserine Externalization Results from and Causes Neurite Degeneration in Drosophila
Published in Cell reports (Cambridge) (28-08-2018)“…Phagocytic clearance of degenerating dendrites or axons is critical for maintaining tissue homeostasis and preventing neuroinflammation. Externalized…”
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6
miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila
Published in PLoS pathogens (01-11-2016)“…microRNAs are endogenous small regulatory RNAs that modulate myriad biological processes by repressing target gene expression in a sequence-specific manner…”
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7
Structure Design of Polymer-Based Films for Passive Daytime Radiative Cooling
Published in Micromachines (Basel) (02-12-2022)“…Passive daytime radiative cooling (PDRC), a cooling method that needs no additional energy, has become increasingly popular in recent years. The combination of…”
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8
An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila
Published in Nature communications (08-10-2018)“…Being relatively simple and practical, Drosophila transgenic RNAi is the technique of top priority choice to quickly study genes with pleiotropic functions…”
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Efficient bi-allelic tagging in human induced pluripotent stem cells using CRISPR
Published in STAR protocols (17-03-2023)“…Allelic tagging of endogenous genes enables studying gene function and transcriptional control in the native genomic context. Here, we present an efficient…”
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P568: Efficient allelic tagging in human induced pluripotent stem cells using CRISPR
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11
Histone H1-mediated epigenetic regulation controls germline stem cell self-renewal by modulating H4K16 acetylation
Published in Nature communications (19-11-2015)“…Epigenetics plays critical roles in controlling stem cell self-renewal and differentiation. Histone H1 is one of the most critical chromatin regulators, but…”
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The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription
Published in PLoS genetics (28-05-2020)“…Dysregulation of CDK8 (Cyclin-Dependent Kinase 8) and its regulatory partner CycC (Cyclin C), two subunits of the conserved Mediator (MED) complex, have been…”
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13
The Lysine Demethylase dKDM2 Is Non-essential for Viability, but Regulates Circadian Rhythms in Drosophila
Published in Frontiers in genetics (04-09-2018)“…Post-translational modification of histones, such as histone methylation controlled by specific methyltransferases and demethylases, play critical roles in…”
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14
Heterochromatin remodeling by CDK12 contributes to learning in Drosophila
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-2015)“…Dynamic regulation of chromatin structure is required to modulate the transcription of genes in eukaryotes. However, the factors that contribute to the…”
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15
Histone H1 defect in escort cells triggers germline tumor in Drosophila ovary
Published in Developmental biology (01-04-2017)“…Drosophila ovary is recognized as one of the best model systems to study stem cell biology in vivo. We had previously identified an autonomous role of the…”
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Enhanced Efficiency of flySAM by Optimization of sgRNA Parameters in Drosophila
Published in G3 : genes - genomes - genetics (01-12-2020)“…The flySAM/CRISPRa system has recently emerged as a powerful tool for gain-of-function studies in This system includes Gal4/UAS-driven dCas9 activators and U6…”
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17
A Toolkit of CRISPR-Based Genome Editing Systems in Drosophila
Published in Journal of genetics and genomics (20-04-2015)“…The last couple of years have witnessed an explosion in development of CRISPR-based genome editing technologies in cell lines as well as in model organisms. In…”
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Genome editing in Drosophila melanogaster: from basic genome engineering to the multipurpose CRISPR-Cas9 system
Published in Science China. Life sciences (01-05-2017)“…Nowadays, genome editing tools are indispensable for studying gene function in order to increase our knowledge of biochemical processes and disease mechanisms…”
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19
Genetically encoded chemical crosslinking of RNA in vivo
Published in Nature chemistry (01-01-2023)“…Protein–RNA interactions regulate RNA fate and function, and defects can lead to various disorders. Such interactions have mainly been studied by…”
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High-throughput CRISPRi and CRISPRa technologies in 3D genome regulation for neuropsychiatric diseases
Published in Human molecular genetics (20-10-2022)“…Advances in genomics have led to the identification of many risk loci with hundreds of genes and thousands of DNA variants associated with neuropsychiatric…”
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