Search Results - "Ren, Xiangmei"
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Rational construction of genome-reduced Burkholderiales chassis facilitates efficient heterologous production of natural products from proteobacteria
Published in Nature communications (23-07-2021)“…Heterologous expression of biosynthetic gene clusters (BGCs) avails yield improvements and mining of natural products, but it is limited by lacking of more…”
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2
Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice
Published in Ecotoxicology and environmental safety (01-11-2021)“…The present work aimed to explore the protective effect of APSP on Pb-induced reproductive toxicity and possible mechanism. APSP (100 mg/kg) was administered…”
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3
Exploring the association and causal effect between white blood cells and psoriasis using large-scale population data
Published in Frontiers in immunology (14-02-2023)“…Psoriasis is a chronic inflammatory disease of the skin. A few studies have shown that psoriasis is an immune-mediated disease in which multiple immune cells…”
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4
Recombineering enables genome mining of novel siderophores in a non-model Burkholderiales strain
Published in Engineering Microbiology (01-09-2023)“…Iron is essential for bacterial survival, and most bacteria capture iron by producing siderophores. Burkholderiales bacteria produce various types of bioactive…”
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5
Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study
Published in Frontiers in nutrition (Lausanne) (2024)“…Recent studies have shown that a higher intake of ascorbic acid was associated with a lower prevalence of depression. Nevertheless, the recall bias was common…”
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Corrigendum: Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study
Published in Frontiers in nutrition (Lausanne) (03-10-2024)“…[This corrects the article DOI: 10.3389/fnut.2024.1375053.]…”
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Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study
Published in Frontiers in nutrition (Lausanne) (27-08-2024)“…Systemic immune-inflammation index (SII) is associated with increased risk in a wide range of illnesses. However, few studies have explored the associations…”
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8
Characterization of intratumor microbiome in cancer immunotherapy
Published in Innovation (New York, NY) (11-09-2023)Get full text
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9
BMI growth trajectory from birth to 5 years and its sex-specific association with prepregnant BMI and gestational weight gain
Published in Frontiers in nutrition (Lausanne) (14-02-2023)“…The purpose of the study was to identify the latent body mass index (BMI) z-score trajectories of children from birth to 5 years of age and evaluate their…”
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10
Liquiritigenin induces mitochondria-mediated apoptosis via cytochrome c release and caspases activation in heLa Cells
Published in Phytotherapy research (01-02-2011)“…It has been demonstrated that many flavonoids possess a potent and broad spectrum of antitumor activity. Liquiritigenin is a flavanone extracted from…”
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11
Cadmium-induced apoptosis through reactive oxygen species-mediated mitochondrial oxidative stress and the JNK signaling pathway in TM3 cells, a model of mouse Leydig cells
Published in Toxicology and applied pharmacology (01-04-2019)“…Cadmium (Cd) is a heavy metal that widely exists in the environment and industry, and which causes serious damages to reproductive system. Recent studies have…”
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Selenium ameliorates cadmium-induced mouse leydig TM3 cell apoptosis via inhibiting the ROS/JNK /c-jun signaling pathway
Published in Ecotoxicology and environmental safety (01-04-2020)“…Despite the well-known acknowledgement of both the toxicity of cadmium (Cd) and the ameliorative effect of selenium (Se), the mechanism of the protective…”
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13
Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway
Published in Chemico-biological interactions (01-11-2021)“…Selenium is an essential trace element for human, and has anti-tumor effects. In this study, we investigated the anti-tumor activity of sodium selenite…”
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14
Astellolides R–W, Drimane-Type Sesquiterpenoids from an Aspergillus parasiticus Strain Associated with an Isopod
Published in Journal of natural products (Washington, D.C.) (28-07-2023)“…Sesquiterpenoids with a cage-like multiring frame are rarely found in nature. Mining of the isopod-derived fungus Aspergillus parasiticus SDU001 by the one…”
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15
Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway
Published in International journal of environmental health research (2021)“…This study was designed to investigate the cytotoxicity of lead acetate (Pb(AC) 2 , a representative air pollutant) by focusing on PPARγ/caspase-3/PARP…”
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16
Nano-selenium Alleviates Cadmium-Induced Mouse Leydig Cell Injury, via the Inhibition of Reactive Oxygen Species and the Restoration of Autophagic Flux
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-06-2023)“…Cadmium (Cd) is a well-known environmental pollutant that can contribute to male reproductive toxicity through oxidative stress. Nano-selenium (Nano-se) is an…”
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17
Discovery of Polycyclic Macrolide Shuangdaolides by Heterologous Expression of a Cryptic trans-AT PKS Gene Cluster
Published in Organic letters (03-09-2021)“…A cryptic trans-acyltransferase polyketide synthase biosynthetic gene cluster sdl (80 kb) from Streptomyces sp. B59 was cloned and transferred into a…”
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18
Biosynthesis of trans-AT PKS-Derived Shuangdaolides Featuring a trans-acting Enzyme for Online Epoxidation
Published in ACS chemical biology (15-12-2023)“…Bacterial trans-acyltransferase polyketide synthases (trans-AT PKSs) synthesize natural products with intricate structures and potent biological activities…”
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Genome-Guided Discovery of Highly Oxygenated Aromatic Polyketides, Saccharothrixins D–M, from the Rare Marine Actinomycete Saccharothrix sp. D09
Published in Journal of natural products (Washington, D.C.) (26-11-2021)“…Angucyclines and angucyclinones are aromatic polyketides with intriguing structures and therapeutic value. Genome mining of the rare marine actinomycete…”
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Saccharochelins A-H, Cytotoxic Amphiphilic Siderophores from the Rare Marine Actinomycete Saccharothrix sp. D09
Published in Journal of natural products (Washington, D.C.) (27-08-2021)“…Siderophores are secreted by microorganisms to survive in iron-depleted conditions, and they also possess tremendous therapeutic potential. Genomic-inspired…”
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