Search Results - "Ren, Shanhui"
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Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections
Published in International journal of molecular sciences (23-05-2020)“…Viruses have evolved different strategies to hijack subcellular organelles during their life cycle to produce robust infectious progeny. Successful viral…”
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ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication
Published in Frontiers in cell and developmental biology (27-07-2021)“…Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative agent for the coronavirus disease 2019 (COVID-19) pandemic and there is an urgent…”
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3
TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro
Published in Frontiers in microbiology (01-12-2023)“…TMP269, a small molecular inhibitor of IIa histone deacetylase, plays a vital role in cancer therapeutic. However, the effect of TMP269 on the regulation of…”
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4
ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells
Published in PLoS pathogens (01-06-2020)“…Deoxyribonucleic acid (DNA) damage response (DDR) is the fundamental cellular response for maintaining genomic integrity and suppressing tumorigenesis. The…”
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Knockout of HDAC9 Gene Enhances Foot-and-Mouth Disease Virus Replication
Published in Frontiers in microbiology (18-02-2022)“…Foot-and-mouth disease virus (FMDV) is a highly contagious viral disease that mainly infects cloven-hoofed animals. Propagation of FMDV by cell culture is an…”
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6
Newcastle disease virus induces testicular damage and disrupts steroidogenesis in specific pathogen free roosters
Published in Veterinary research (Paris) (29-06-2020)“…Newcastle disease (ND), which is caused by Newcastle disease virus (NDV), can cause heavy economic losses to the poultry industry worldwide. It is…”
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Supplementation of Vitamin E Protects Chickens from Newcastle Disease Virus-Mediated Exacerbation of Intestinal Oxidative Stress and Tissue Damage
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Newcastle disease virus (NDV) causes a highly devastating and contagious disease in poultry, which is mainly attributed to extensive tissue…”
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Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion-fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress
Published in Veterinary research (Paris) (22-05-2019)“…The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 and A549 cells. However, the effect of both glycoproteins…”
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Identification of Newcastle disease virus P-gene editing using next-generation sequencing
Published in Journal of Veterinary Medical Science (2020)“…Avian paramyxoviruses 1 has the ability to edit its P gene to generate three amino-coterminal proteins (P, V and W), but its kinetic change is unclear. In this…”
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10
Foot-and-Mouth Disease Virus Capsid Protein VP1 Antagonizes Type I Interferon Signaling via Degradation of Histone Deacetylase 5
Published in Cells (Basel, Switzerland) (19-03-2024)“…Foot-and-mouth disease (FMD) is a highly contagious and economically important disease of cloven-hoofed animals that hampers trade and production. To ensure…”
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11
The 16S rRNA Gene Sequencing of Gut Microbiota in Chickens Infected with Different Virulent Newcastle Disease Virus Strains
Published in Animals (Basel) (24-09-2022)“…Newcastle disease virus (NDV) which is pathogenic to chickens is characterized by dyspnea, diarrhea, nervous disorder and hemorrhages. However, the influence…”
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12
Full Genomic Characterization of a Lentogenic Newcastle Disease Virus Isolated from Farm-Reared Ostriches ( Struthio camelus ) in Northwest China
Published in Genome announcements (Washington, DC) (09-02-2017)“…To our knowledge, our study is the first to report the whole-genome sequence of an ostrich-origin Newcastle disease virus (NDV) isolate, abbreviated as…”
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Lumpy skin disease virus enters into host cells via dynamin-mediated endocytosis and macropinocytosis
Published in Veterinary microbiology (01-11-2024)“…Lumpy skin disease virus (LSDV), a ruminant poxvirus of the Capripoxvirus genus, is the etiologic agent of an economically important cattle disease categorized…”
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14
Platform establishment of the Cre-loxP recombination system for genetic manipulation of the Lumpy skin disease virus
Published in Veterinary microbiology (01-07-2024)“…Lumpy skin disease virus (LSDV) is a rapidly emerging pathogen in Asia, including China. Genetic manipulation of the LSDV is essential for the elucidation of…”
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Phylogenetic and pathogenic characterization of lumpy skin disease virus circulating in China
Published in Virology (New York, N.Y.) (01-08-2023)“…The genomic characterization of emerging pathogens is critical for unraveling their origin and tracking their dissemination. Lumpy skin disease virus (LSDV) is…”
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Lumpy skin disease virus ORF127 protein suppresses type I interferon responses by inhibiting K63‐linked ubiquitination of tank binding kinase 1
Published in The FASEB journal (15-02-2024)“…Lumpy skin disease (LSD) is a severe animal infectious disease caused by lumpy skin disease virus (LSDV), inducing extensive nodules on the cattle mucosa or…”
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Newcastle disease virus infection triggers HMGB1 release to promote the inflammatory response
Published in Virology (New York, N.Y.) (01-12-2018)“…High mobility group box 1 (HMGB1) is a key member of the “danger associated molecular patterns” (DAMPs) which plays important roles in systemic inflammation…”
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Establishment of a fetal cow (Bos Borus) skin fibroblasts cell line with immortalized characterization through human telomerase reverse transcriptase (hTERT) ectopic expression
Published in Journal of virological methods (01-11-2022)“…The ectopic introduction of the human telomerase reverse transcriptase (hTERT) is an effective way to establish an immortalized cell line. Here, hTERT was…”
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9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β
Published in Journal of virology (30-03-2023)“…The paramyxoviruses represent a large family of human and animal pathogens that cause significant health and economic burdens worldwide. However, there are no…”
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Molecular characterization, expression, and functional identification of TANK-binding kinase 1 (TBK1) of the cow (Bos taurus) and goat (Capra hircus)
Published in Developmental and comparative immunology (01-08-2022)“…The role of TANK-binding kinase 1 (TBK1) of humans and mice in innate immunity is well elucidated. Still, the molecular characterization and biological…”
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