Search Results - "Ren, Hongguang"
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In vivo structure and dynamics of the SARS-CoV-2 RNA genome
Published in Nature communications (28-09-2021)“…The dynamics of SARS-CoV-2 RNA structure and their functional relevance are largely unknown. Here we develop a simplified SPLASH assay and comprehensively map…”
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Predicting the transmission trend of respiratory viruses in new regions via geospatial similarity learning
Published in International journal of applied earth observation and geoinformation (01-12-2023)“…The outbreak and spread of COVID-19 remind us again of the devastating attack that human-to-human transmitted respiratory infectious diseases (H-HRIDs) bring…”
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Genome-based classification of Burkholderia cepacia complex provides new insight into its taxonomic status
Published in Biology direct (04-03-2020)“…Accurate classification of different Burkholderia cepacia complex (BCC) species is essential for therapy, prognosis assessment and research. The taxonomic…”
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Comparative genomic analysis provides insights into the genetic diversity and pathogenicity of the genus Brucella
Published in Frontiers in microbiology (24-04-2024)“…Some spp. are important pathogens. According to the latest prokaryotic taxonomy, the genus consists of facultative intracellular parasitic species and…”
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Spatio-temporal spread and evolution of Lassa virus in West Africa
Published in BMC infectious diseases (14-03-2024)“…Lassa fever is a hemorrhagic disease caused by Lassa virus (LASV), which has been classified by the World Health Organization as one of the top infectious…”
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Characterization and Diversity of Klebsiella pneumoniae Prophages
Published in International journal of molecular sciences (23-05-2023)“…is a common human commensal and opportunistic pathogen. In recent years, the clinical isolation and resistance rates of have shown a yearly increase, leading…”
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Origin and Possible Genetic Recombination of the Middle East Respiratory Syndrome Coronavirus from the First Imported Case in China: Phylogenetics and Coalescence Analysis
Published in mBio (08-09-2015)“…The Middle East respiratory syndrome coronavirus (MERS-CoV) causes a severe acute respiratory tract infection with a high fatality rate in humans…”
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Reassortment Network of Influenza A Virus
Published in Frontiers in microbiology (16-12-2021)“…Influenza A virus (IAV) genomes are composed of eight single-stranded RNA segments. Genetic exchange through reassortment of the segmented genomes often endows…”
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Comparative genomics reveals new insights into the evolution of the IncA and IncC family of plasmids
Published in Frontiers in microbiology (16-11-2022)“…Incompatibility groups IncA and IncC plasmids are of great concern due to their ability to disseminate antibiotic resistance in bacteria via conjugative…”
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Global Mutational Sweep of SARS-CoV-2: From Chaos to Order
Published in Frontiers in microbiology (08-02-2022)Get full text
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Detecting genetic gain and loss events in terms of protein domain: Method and implementation
Published in Heliyon (15-06-2024)“…Continuous gain and loss of genes are the primary driving forces of bacterial evolution and environmental adaptation. Studying bacterial evolution in terms of…”
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Evaluating the effect of SARS-CoV-2 spike mutations with a linear doubly robust learner
Published in Frontiers in cellular and infection microbiology (19-04-2023)“…Driven by various mutations on the viral Spike protein, diverse variants of SARS-CoV-2 have emerged and prevailed repeatedly, significantly prolonging the…”
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Characterizing the Core Internal Gene Pool of H9N2 Responsible for Continuous Reassortment With Other Influenza A Viruses
Published in Frontiers in microbiology (16-12-2021)“…Reassortment among avian influenza viruses is the main source of novel avian influenza virus subtypes. Studies have shown that the H9N2 virus often donates…”
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Characterization of Burkholderia cepacia Complex Core Genome and the Underlying Recombination and Positive Selection
Published in Frontiers in genetics (21-05-2020)“…Recombination and positive selection are two key factors that play a vital role in pathogenic microorganisms’ population adaptation and diversification. The…”
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Genetic Characteristic and Global Transmission of Influenza A H9N2 Virus
Published in Frontiers in microbiology (22-12-2017)“…The H9N2 virus has been demonstrated to donate its genes to other subtypes of influenza A virus, forming new reassortant virus which may infect human beings…”
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A Vaccine Based on the Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2 Stimulates Neutralizing and Protective Antibody Responses
Published in Engineering (Beijing, China) (01-06-2022)“…In 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, caused a global pandemic. Vaccines are expected to reduce…”
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A Non-phylogeny-dependent Reassortment Detection Method for Influenza A Viruses
Published in Frontiers in virology (online) (07-12-2021)“…Influenza A virus is a segmented RNA virus whose genome consists of 8 single-stranded negative-sense RNA segments. This unique genetic structure allows viruses…”
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Different Subtypes of Influenza Viruses Target Different Human Proteins and Pathways Leading to Different Pathogenic Phenotypes
Published in BioMed research international (2019)“…Different subtypes of influenza A viruses (IAVs) cause different pathogenic phenotypes after infecting human bodies. Analysis of the interactions between viral…”
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DSS: Applying asynchronous techniques to architectures exploiting ILP at compile time
Published in 2010 IEEE International Conference on Computer Design (01-10-2010)“…Embedded application environments require both high performance and low power. Architectures exploiting instruction-level parallelism (ILP) at compile time,…”
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