Search Results - "Ren, Chunyan"
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Accumulation, ecological-health risks assessment, and source apportionment of heavy metals in paddy soils: A case study in Hanzhong, Shaanxi, China
Published in Environmental pollution (1987) (01-05-2019)“…Contamination of agricultural soil by heavy metals has become a global issue concerning food security and human health risk. In this study, a soil…”
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Therapeutic base editing of human hematopoietic stem cells
Published in Nature medicine (01-04-2020)“…Base editing by nucleotide deaminases linked to programmable DNA-binding proteins represents a promising approach to permanently remedy blood disorders,…”
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Highly efficient therapeutic gene editing of human hematopoietic stem cells
Published in Nature medicine (01-05-2019)“…Re-expression of the paralogous γ-globin genes ( HBG1/2 ) could be a universal strategy to ameliorate the severe β-globin disorders sickle cell disease (SCD)…”
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Performance of the emerging biochar on the stabilization of potentially toxic metals in smelter- and mining-contaminated soils
Published in Environmental science and pollution research international (01-12-2020)“…Soil potentially toxic metals (PTMs) pollution caused by anthropogenic activities has become serious concern with respect to the crop safety production. In…”
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Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation
Published in Molecular cell (16-03-2017)“…The BET proteins are major transcriptional regulators and have emerged as new drug targets, but their functional distinction has remained elusive. In this…”
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Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis
Published in Nature genetics (01-07-2019)“…Developmental silencing of fetal globins serves as both a paradigm of spatiotemporal gene regulation and an opportunity for therapeutic intervention of…”
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Novel rhamnolipid biosurfactants produced by a polycyclic aromatic hydrocarbon-degrading bacterium Pseudomonas aeruginosa strain NY3
Published in Biotechnology advances (01-09-2010)“…A novel rhamnolipid biosurfactant-producing and Polycyclic Aromatic Hydrocarbon (PAH)-degrading bacterium Pseudomonas aeruginosa strain NY3 was isolated from…”
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PHISDetector: A Tool to Detect Diverse In Silico Phage–host Interaction Signals for Virome Studies
Published in Genomics, proteomics & bioinformatics (01-06-2022)“…Phage–microbe interactions are appealing systems to study coevolution, and have also been increasingly emphasized due to their roles in human health, disease,…”
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Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2018)“…The importance of BET protein BRD4 in gene transcription is well recognized through the study of chemical modulation of its characteristic tandem bromodomain…”
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Voluntary CSR disclosure, institutional environment, and independent audit demand
Published in China journal of accounting research (01-12-2019)“…Using a sample of A-share listed companies on the Shanghai and Shenzhen Stock Exchanges, this study examines the impact of voluntary corporate social…”
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Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
Published in Molecular cell (06-07-2023)“…Histone lysine acylation, including acetylation and crotonylation, plays a pivotal role in gene transcription in health and diseases. However, our…”
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Screening and identification of lncRNAs in preadipocyte differentiation in sheep
Published in Scientific reports (04-03-2024)“…Studies of preadipocyte differentiation and fat deposition in sheep have mainly focused on functional genes, and with no emphasis placed on the role that long…”
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Fli-1 Activation through Targeted Promoter Activity Regulation Using a Novel 3', 5'-diprenylated Chalcone Inhibits Growth and Metastasis of Prostate Cancer Cells
Published in International journal of molecular sciences (23-03-2020)“…The friend leukemia integration 1 (Fli-1) gene is involved in the expression control of key genes in multiple pathogenic/physiological processes, including…”
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Dissecting ELANE neutropenia pathogenicity by human HSC gene editing
Published in Cell stem cell (06-05-2021)“…Severe congenital neutropenia (SCN) is a life-threatening disorder most often caused by dominant mutations of ELANE that interfere with neutrophil maturation…”
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MicroRNA-148a Targets DNMT1 and PPARGC1A to Regulate the Viability, Proliferation, and Milk Fat Synthesis of Ovine Mammary Epithelial Cells
Published in International journal of molecular sciences (06-08-2024)“…In this study, the expression profiles of miR-148a were constructed in eight different ovine tissues, including mammary gland tissue, during six different…”
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Performance of Streptomyces pactum–assisted phytoextraction of Cd and Pb: in view of soil properties, element bioavailability, and phytoextraction indices
Published in Environmental science and pollution research international (01-12-2020)“…Microbe-assisted phytoremediation provides an eco-friendly and cost-effective approach to reclaim Cd- and Pb-contaminated soils. In this work, incubation and…”
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Molecular Characteristics of JAK2 and Its Effect on the Milk Fat and Casein Synthesis of Ovine Mammary Epithelial Cells
Published in International journal of molecular sciences (01-04-2024)“…In addition to its association with milk protein synthesis via the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, also…”
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DBSCAN-SWA: An Integrated Tool for Rapid Prophage Detection and Annotation
Published in Frontiers in genetics (19-04-2022)“…As an intracellular form of a bacteriophage in the bacterial host genome, a prophage usually integrates into bacterial DNA with high specificity and…”
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A mild and simple method to fabricate commercial TiO2 (P25) and C60 composite for highly enhancing H2 generation
Published in International journal of hydrogen energy (24-01-2020)“…Photocatalytic hydrogen evolution from water is a valid method to face the challenge of energy shortage. TiO2, as the most well-known and investigated…”
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Tunable Luminescence in Sr2MgSi2O7:Tb3+, Eu3+Phosphors Based on Energy Transfer
Published in Materials (24-02-2017)“…A series of Tb3+, Eu3+-doped Sr2MgSi2O7 (SMSO) phosphors were synthesized by high temperature solid-state reaction. X-ray diffraction (XRD) patterns, Rietveld…”
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