Search Results - "Ren, Chien Tai"

An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3 by Kizuka, Yasuhiko, Nakano, Miyako, Yamaguchi, Yoshiki, Nakajima, Kazuki, Oka, Ritsuko, Sato, Keiko, Ren, Chien-Tai, Hsu, Tsui-Ling, Wong, Chi-Huey, Taniguchi, Naoyuki

“…Fucosylation is a glycan modification critically involved in cancer and inflammation. Although potent fucosylation inhibitors are useful for basic and clinical…”
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Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies by Shivatare, Sachin S., Chang, Shih-Huang, Tsai, Tsung-I, Tseng, Susan Yu, Shivatare, Vidya S., Lin, Yih-Shyan, Cheng, Yang-Yu, Ren, Chien-Tai, Lee, Chang-Chun David, Pawar, Sujeet, Tsai, Charng-Sheng, Shih, Hao-Wei, Zeng, Yi-Fang, Liang, Chi-Hui, Kwong, Peter D., Burton, Dennis R., Wu, Chung-Yi, Wong, Chi-Huey

“…A new class of broadly neutralizing antibodies (bNAbs) from HIV donors has been reported to target the glycans on gp120—a glycoprotein found on the surface of…”
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Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer by Huang, Yen-Lin, Hung, Jung-Tung, Cheung, Sarah K. C., Lee, Hsin-Yu, Chu, Kuo-Ching, Li, Shiou-Ting, Lin, Yu-Chen, Ren, Chien-Tai, Cheng, Ting-Jen R., Hsu, Tsui-Ling, Yu, Alice L., Wu, Chung-Yi, Wong, Chi-Huey

“…Globo H (GH) is a hexasaccharide specifically overexpressed on a variety of cancer cells and therefore, a good candidate for cancer vaccine development. To…”
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Highly Alpha-Selective Sialyl Phosphate Donors for Efficient Preparation of Natural Sialosides by Hsu, Che-Hsiung, Chu, Kuo-Ching, Lin, Yih-Shyan, Han, Jeng-Liang, Peng, Yu-Shiang, Ren, Chien-Tai, Wu, Chung-Yi, Wong, Chi-Huey

“…Hubble, bubble, toil, and trouble: The use of a new sialyl phosphate donor allows the stereoselective, one‐pot multicomponent synthesis of…”
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Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases by Lin, Tzu-Lung, Yang, Feng-Ling, Ren, Chien-Tai, Pan, Yi-Jiun, Liao, Kuo-Shiang, Tu, I-Fan, Chang, Yu-Pei, Cheng, Yang-Yu, Wu, Chung-Yi, Wu, Shih-Hsiung, Wang, Jin-Town

“…is an important pathogen associated with nosocomial infection and has developed increasing resistance to antibiotics such as extended-spectrum β-lactams and…”
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Synthesis of Asymmetric N‑Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation by Pawar, Sujeet, Hsu, Li, Narendar Reddy, Thatikonda, Ravinder, Mettu, Ren, Chien-Tai, Lin, Yu-Wei, Cheng, Yang-Yu, Lin, Tzu-Wen, Hsu, Tsui-Ling, Wang, Sheng-Kai, Wong, Chi-Huey, Wu, Chung-Yi

“…N-glycans on the cell surface provide distinct signatures that are recognized by different glycan-binding proteins (GBPs) and pathogens. Most glycans in humans…”
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Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer by Wang, Cheng-Chi, Huang, Yen-Lin, Ren, Chien-Tai, Lin, Chin-Wei, Hung, Jung-Tung, Yu, Jyh-Cherng, Yu, Alice L, Wu, Chung-Yi, Wong, Chi-Huey

“…Cancer-associated carbohydrate antigens are often found on the surface of cancer cells. Understanding their roles in cancer progression will lead to the…”
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Cancer-associated carbohydrate antigens as potential biomarkers for hepatocellular carcinoma by Wu, Chen-Shiou, Yen, Chia-Jui, Chou, Ruey-Hwang, Li, Shiou-Ting, Huang, Wei-Chien, Ren, Chien-Tai, Wu, Chung-Yi, Yu, Yung-Luen

“…Hepatocellular carcinoma (HCC) is one of the most common human malignancies. Therefore, developing the early, high-sensitivity diagnostic biomarkers to prevent…”
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Synthesis and Vaccine Evaluation of the Tumor-Associated Carbohydrate Antigen RM2 from Prostate Cancer by Chuang, Hong-Yang, Ren, Chien-Tai, Chao, Chung-An, Wu, Chung-Yi, Shivatare, Sachin S, Cheng, Ting-Jen R, Wu, Chung-Yi, Wong, Chi-Huey

“…We have successfully developed a [1+2+3] one-pot strategy to synthesize the RM2 antigen hexasaccharide that was proposed to be a prostate tumor antigen. The…”
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Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes by Liao, Shih-Fen, Liang, Chi-Hui, Ho, Ming-Yi, Hsu, Tsui-Ling, Tsai, Tsung-I, Hsieh, Yves S.-Y., Tsai, Chih-Ming, Li, Shiou-Ting, Cheng, Yang-Yu, Tsao, Shu-Ming, Lin, Tung-Yi, Lin, Zong-Yan, Yang, Wen-Bin, Ren, Chien-Tai, Lin, Kuo-I, Khoo, Kay-Hooi, Lin, Chun-Hung, Hsu, Hsien-Yeh, Wu, Chung-Yi, Wong, Chi-Huey

“…Carbohydrate-based vaccines have shown therapeutic efficacy for infectious disease and cancer. The mushroom Ganoderma lucidum (Reishi) containing complex…”
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Differential Receptor Binding Affinities of Influenza Hemagglutinins on Glycan Arrays by Liao, Hsin-Yu, Hsu, Che-Hsiung, Wang, Shih-Chi, Liang, Chi-Hui, Yen, Hsin-Yung, Su, Ching-Yao, Chen, Chien-Hung, Jan, Jia-Tsrong, Ren, Chien-Tai, Chen, Chung-Hsuan, Cheng, Ting-Jen R, Wu, Chung-Yi, Wong, Chi-Huey

“…A library of 27 sialosides, including seventeen 2,3-linked and ten 2,6-linked glycans, has been prepared to construct a glycan array and used to profile the…”
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Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids: From Monomers to Dodecamers by Chu, Kuo-Ching, Ren, Chien-Tai, Lu, Chun-Ping, Hsu, Che-Hsiung, Sun, Tsung-Hsien, Han, Jeng-Liang, Pal, Bikash, Chao, Tsung-An, Lin, Yung-Feng, Wu, Shih-Hsiung, Wong, Chi-Huey, Wu, Chung-Yi

“…The chain gang: The α(2→9) dodecasialic acid has been stereoselectively synthesized in 12 steps by using a convergent block synthesis (see scheme). The use of…”
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Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation by Chen, Chiang-Yun, Lin, Yu-Wei, Wang, Szu-Wen, Lin, Yung-Chu, Cheng, Yang-Yu, Ren, Chien-Tai, Wong, Chi-Huey, Wu, Chung-Yi

“…Globo H (GH) is a tumor-associated carbohydrate antigen (TACA), and GH conjugations have been evaluated as potential cancer vaccines. However, like all…”
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Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin by Chen, Ming-Wei, Liao, Hsin-Yu, Huang, Yaoxing, Jan, Jia-Tsrong, Huang, Chih-Cheng, Ren, Chien-Tai, Wu, Chung-Yi, Cheng, Ting-Jen Rachel, Ho, David D, Wong, Chi-Huey

“…The rapid genetic drift of influenza virus hemagglutinin is an obstacle to vaccine efficacy. Previously, we found that the consensus hemagglutinin DNA vaccine…”
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Desorption Ionization of Biomolecules on Metals by Hsu, Nien-Yeen, Tseng, Susan Yu, Wu, Chung-Yi, Ren, Chien-Tai, Lee, Yuan-Chang, Wong, Chi-Huey, Chen, Chung-Hsuan

“…Direct desorption ionization of various types of biomolecules on metal substrates without the need of matrices was observed by a time-of-flight mass…”
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Development of an Activity-Based Probe for Steroid Sulfatases by Lu, Chun-Ping, Ren, Chien-Tai, Wu, Shih-Hsiung, Chu, Chi-Yuan, Lo, Lee-Chiang

“…Selecting sulfatase. By loading probe 1 onto beads, we have demonstrated a protocol that allows for the selective labeling of a human steroid sulfatase (STS)…”
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Chemical Probes for Drug-Resistance Assessment by Binding Competition (RABC): Oseltamivir Susceptibility Evaluation by Cheng, Ting-Jen R., Wang, Shi-Yun, Wen, Wen-Hsien, Su, Ching-Yao, Lin, Mengi, Huang, Wen-I, Liu, Ming-Tsan, Wu, Ho-Sheng, Wang, Nung-Sen, Cheng, Chung-Kai, Chen, Chun-Lin, Ren, Chien-Tai, Wu, Chung-Yi, Fang, Jim-Min, Cheng, Yih-Shyun E., Wong, Chi-Huey

“…The wizard of OS (resistance): The binding difference of neuraminidase inhibitors (zanamivir versus oseltamivir (OS)) was used to establish an assay to…”
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Design of a Mechanism-Based Probe for Neuraminidase To Capture Influenza Viruses by Lu, Chun-Ping, Ren, Chien-Tai, Lai, Yi-Ning, Wu, Shih-Hsiung, Wang, Wei-Man, Chen, Jean-Yin, Lo, Lee-Chiang

“…Getting a grip on the flu: A mechanism‐based probe, 1, for neuraminidase was developed. It is capable of forming a biotinylated adduct with neuraminidase (NA)…”
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Pseudaminic Acid on Exopolysaccharide of Acinetobacter baumannii Plays a Critical Role in Phage-Assisted Preparation of Glycoconjugate Vaccine with High Antigenicity by Lee, I-Ming, Yang, Feng-Ling, Chen, Te-Li, Liao, Kuo-Shiang, Ren, Chien-Tai, Lin, Nien-Tsung, Chang, Yu-Pei, Wu, Chung-Yi, Wu, Shih-Hsiung

“…Pseudaminic acid (Pse) has been known for participating in crucial bacterial virulence and thus is an attractive target in the development of glycoconjugate…”
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Enhancement of fucosylated N-glycan isomer separation with an ultrahigh column temperature in porous graphitic carbon liquid chromatography-mass spectrometry by Chen, Chein-Hung, Lin, Ya-Ping, Ren, Chien-Tai, Shivatare, Sachin S., Lin, Nan-Hon, Wu, Chung-Yi, Chen, Chung-Hsuan, Lin, Jung-Lee

“…•The advantage of UHT-PGC column had high peak capacity and selectivity for native glycans.•UHT-PGC-LC-MSMS provided the RIR of diagnostic ions to predict…”
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