Search Results - "Ren, Binhai"

Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells by Simpson, Ann, Nassif, Najah, Ren, Binhai, Habib, Rosaline, Martiniello-Wilks, Rosetta, Gerace, Dario, O’Brien, Bronwyn Anne

“…Combinatorial gene and cell therapy as a means of generating surrogate β-cells has been investigated for the treatment of type 1 diabetes (T1D) for a number of…”
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Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice by La, Que T, Ren, Binhai, Logan, Grant J, Cunningham, Sharon C, Khandekar, Neeta, Nassif, Najah T, O'Brien, Bronwyn A, Alexander, Ian E, Simpson, Ann M

“…Previously, we used a lentiviral vector to deliver furin-cleavable human insulin ( ) to the livers in several animal models of diabetes using intervallic…”
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Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line by Ren, Binhai, Tao, Chang, Swan, Margaret Anne, Joachim, Nichole, Martiniello-Wilks, Rosetta, Nassif, Najah T, O'Brien, Bronwyn A, Simpson, Ann M

“…Due to the limitations of current treatment regimes, gene therapy is a promising strategy being explored to correct blood glucose concentrations in diabetic…”
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Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells by Lawandi, Janet, Tao, Chang, Ren, Binhai, Williams, Paul, Ling, Dora, Swan, M Anne, Nassif, Najah T, Torpy, Fraser R, O'Brien, Bronwyn A, Simpson, Ann M

“…As an alternative to the transplantation of islets, a human liver cell line has been genetically engineered to reverse type 1 diabetes (TID). The initial liver…”
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Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic [beta]-Cells by Habib, Rosaline, O'Brien, Bronwyn Anne, Nassif, Najah Therese, Simpson, Ann Margaret, Martiniello-Wilks, Rosetta, Ren, Binhai, Gerace, Dario

“…Combinatorial gene and cell therapy as a means of generating surrogate [beta]-cells has been investigated for the treatment of type 1 diabetes (T1D) for a…”
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1778-P: Delivery of the Insulin Gene Using an Integrating Adeno-Associated Viral Vector (AAV) to Diabetic NOD Mice by LA, QUE T., REN, BINHAI, LOGAN, GRANT J., CUNNINGHAM, SHARON C., KHANDEKAR, NEETA, NASSIF, NAJAH T., O'BRIEN, BRONWYN A., ALEXANDER, IAN E., SIMPSON, ANN M.

“…Previously we introduced furin-cleavable human insulin (INSFUR) to the livers in several animal models using a lentiviral vector. Reversal of diabetes with…”
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High-Efficiency Lentiviral Gene Modification of Primary Murine Bone-Marrow Mesenchymal Stem Cells by Gerace, Dario, Ren, Binhai, Martiniello-Wilks, Rosetta, Simpson, Ann M

“…Lentiviral vectors are the method of choice for stable gene modification of a variety of cell types. However, the efficiency with which they transduce target…”
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275. Pancreatic Transdiffereniation of Human Hepatocytes in the Livers of a Humanized Mouse Model by Ren, Binhai, O'Brien, Bronwyn A., Alexander, Ian E., Nassif, Najah T., Tan, Yi, Martiniello-Wilks, Rosetta, Simpson, Ann M.

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Partial pancreatic transdifferentiation of primary human hepatocytes in the livers of a humanised mouse model by Ren, Binhai, La, Que T., O'Brien, Bronwyn A., Nassif, Najah T., Tan, Yi, Gerace, Dario, Martiniello‐Wilks, Rosetta, Torpy, Fraser, Dane, Allison P., Alexander, Ian E., Simpson, Ann M.

“…Background Gene therapy is one treatment that may ultimately cure type 1 diabetes. We have previously shown that the introduction of furin‐cleavable human…”
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Long-term reversal of diabetes in non-obese diabetic mice by liver-directed gene therapy by Ren, Binhai, O'Brien, Bronwyn A., Byrne, Michelle R., Ch'ng, Edwin, Gatt, Prudence N., Swan, M. Anne, Nassif, Najah T., Wei, Ming Q., Gijsbers, Rik, Debyser, Zeger, Simpson, Ann M.

“…Background Type 1 diabetes (T1D) results from an autoimmune attack against the insulin‐producing β‐cells of the pancreas. The present study aimed to reverse…”
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Response to the letter to the editor by M. Elsner et al: "Comment on Binhai Ren et al (2013;15:28-41). Long term reversal of diabetes in non-obese diabetic mice by liver-directed gene therapy" by Simpson, Ann M., Ren, Binhai, O'Brien, Bronwyn A., Nassif, Najah T.

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A new vascularized skin transplant model in rats by Ren, Binhai, Sun, Junhong, Painter, Dorothy M., Sheil, A.G. Ross

“…The aim of this work was to develop a vascularized skin transplantation model in the rat to allow comparison of the immunological events with those of classic…”
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