Search Results - "Rempel, Julia D"

Hepatitis C virus in American Indian/Alaskan Native and Aboriginal peoples of North America by Rempel, Julia D, Uhanova, Julia

“…Liver diseases, such as hepatitis C virus (HCV) infection, are "broken spirit" diseases. The prevalence of HCV infection for American Indian/Alaskan Native…”
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Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K by Curzio, Domenico Di, Gurm, Mamneet, Turnbull, Matthew, Nadeau, Marie-Josée, Meek, Breanna, Rempel, Julia D, Fineblit, Samuel, Jonasson, Michael, Hebert, Sherry, Ferguson-Parry, Jennifer, Douville, Renée N

“…Motor neuron degeneration and spinal cord demyelination are hallmark pathological events in Amyotrophic Lateral Sclerosis (ALS). Endogenous retrovirus-K (ERVK)…”
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Preliminary analysis of immune activation in early onset type 2 diabetes by Rempel, Julia D., Packiasamy, Juliet, Dean, Heather J., McGavock, Jonathon, Janke, Alyssa, Collister, Mark, Wicklow, Brandy, Sellers, Elizabeth A. C.

“…First Nations and other Aboriginal children are disproportionately affected by cardiometabolic diseases, including type 2 diabetes (T2D). In T2D, the…”
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Differential regulation of innate and adaptive immune responses in viral encephalitis by Rempel, Julia D, Murray, Shannon J, Meisner, Jeffrey, Buchmeier, Michael J

“…Viral encephalitis is a global health concern. The ability of a virus to modulate the immune response can have a pivotal effect on the course of disease and…”
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Plasma Oxylipins Levels in Nonalcoholic Fatty Liver Disease by Li, Qian, Rempel, Julia D., Ball, Terry B., Aukema, Harold, Minuk, Gerald Y.

“…Background Activation of innate immunity by gut-derived immunogens such as lipopolysaccharides (LPS) may play an important role in the pathogenesis of…”
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The Effects of Pathogen-Associated Molecular Patterns on Peripheral Blood Monocytes in Patients with Non-alcoholic Fatty Liver Disease by Li, Qian, Rempel, Julia D., Yang, Jiaqi, Minuk, Gerald Y.

“…Innate immune responses to gut-derived pathogen-associated molecular patterns (PAMPs) have been implicated in the pathogenesis of nonalcoholic fatty liver…”
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Activation of β-adrenergic receptors increases the in vitro migration of malignant hepatocytes by Lodewyks, Carly, Rodriguez, Jose F., Yan, Jing, Lerner, Betty, Sun, DongFeng, Rempel, Julia D., Uhanova, Julia, Labine, Meaghan, Minuk, Gerald Y.

“…Aim:  Activation of adrenergic receptors (AR) has been reported to enhance the growth and invasion of various malignancies. The effects of AR agonists on…”
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Involvement of fibrinolytic regulators in adhesion of monocytes to vascular endothelial cells induced by glycated LDL and to aorta from diabetic mice by Zhao, Ruozhi, Ren, Song, Moghadasain, Mohammed H., Rempel, Julia D., Shen, Garry X.

“…Oxidative stress and fibrinolytic regulators are involved in glycated LDL‐induced monocyte adhesion to vascular endothelial cells and increased monocyte…”
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Distribution of viral hepatitis in indigenous populations of North America and the circumpolar Arctic by Osiowy, Carla, Simons, Brenna C, Rempel, Julia D

“…The burden of viral hepatitis among indigenous populations of the United States, Canada and Greenland is greater than in non-indigenous populations. In…”
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The potential influence of KIR cluster profiles on disease patterns of Canadian Aboriginals and other indigenous peoples of the Americas by REMPEL, Julia D, HAWKINS, Kim, LANDE, Erin, NICKERSON, Peter

“…Genetic differences in immune regulators influence disease resistance and susceptibility patterns. There are major health discrepancies in immune-mediated…”
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Impact of aboriginal ethnicity on HCV core‐induced IL‐10 synthesis: Interaction with IL‐10 gene polymorphisms by Aborsangaya, Koko Bate, Dembinski, Iga, Khatkar, Suresh, Alphonse, Martin Prince, Nickerson, Peter, Rempel, Julia D.

“…The host immune response is a critical determinant in viral infection outcome. Epidemiological studies indicate that North American indigenous peoples are more…”
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The Influence of Hepatitis C Viral Loads on Natural Killer Cell Function by Collister, Mark, Ellison, Cindy, Li, Qian, Minuk, Gerald Y, Rempel, Julia D, Kung, Sam K

“…Hepatitis C virus (HCV) infection has a high rate of chronicity, attributable to its capacity to alter host immunity, including natural killer (NK) cell…”
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HCV protein-induced cytokine predicts treatment outcomes in chronic hepatitis C virus infection by Krueger, Carla, Collister, Mark, Minuk, Gerald Y., Janke, Alyssa, Lerner, Jordyn, Wong, Stephen G. M., Rempel, Julia D.

“…Background & Aims Immune‐mediated processes are thought to influence the efficacy of treatment in chronic hepatitis C virus (HCV) infection. This study…”
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Immune Pathology of Type 2 Diabetes in First Nation Youth by Rempel, Julia D, Packiasamy, Juliet, Sellers, Elizabeth, Wicklow, Brandy, Dean, Heather

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Baseline Comorbidities Enhance the Risk of Treatment-Induced Depression in HCV-Infected Men: A Pilot Study by Rempel, Julia D, Krueger, Carla, Minuk, Gerald Y, Wong, Stephen G M

“…Hepatitis C virus (HCV) infection is associated with clinical depression,a condition that is aggravated on interferon-based therapy. In HCV infection, men…”
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Baseline Comorbidities Enhance the Risk of Treatment-Induced Depression in HCV-Infected Men by Julia D. Rempel PhD, Carla Krueger MSc, Gerald Y. Minuk MD FRCP, Stephen G.M. Wong MD

“…Background. Hepatitis C virus (HCV) infection is associated with clinical depression,a condition that is aggravated on interferon-based therapy. In HCV…”
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Mouse hepatitis virus neurovirulence: evidence of a linkage between S glycoprotein expression and immunopathology by Rempel, Julia D, Murray, Shannon J, Meisner, Jeffrey, Buchmeier, Michael J

“…Differences in disease outcome between the highly neurovirulent MHV-JHM and mildly neurovirulent MHV-A59 have been attributed to variations within the spike…”
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Prevention of Allergen-Specific, Th2-Biased Immune Responses In Vivo: Role of Increased IL-12 and IL-18 Responsiveness by Lewkowich, Ian P, Rempel, Julia D, HayGlass, Kent T

“…The factors that control development of adaptive responses to exogenous Ag remain incompletely understood. An ability to selectively direct immunity toward a…”
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Antigen-specific versus total immunoglobulin synthesis: total IgE and IgG1, but not IgG2a levels predict murine antigen-specific responses by Lewkowich, Ian P, Rempel, Julia D, HayGlass, Kent T

“…Induction of an effective antibody (Ab) response requires delivery of multiple signals to B cells. Cross-linking of the B cell antigen receptor (BCR),…”
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Autoantibodies exacerbate the severity of MHV-induced encephalitis by Burrer, Renaud, von Herrath, Matthias G, Wolfe, Tom, Rempel, Julia D, Iglesias, Antonio, Buchmeier, Michael J

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