Search Results - "Rempel, Jeremy"

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial by McTaggart, Ryan A, Poppe, Alexandre Y, Swartz, Richard H, Sauvageau, Eric, Ospel, Johanna M, Yu, Amy Y X, Silver, Frank L, Mandzia, Jennifer L, Bharatha, Aditya, McDougall, Cameron G, Sohn, Sung-Il, Almekhlafi, Mohammed, Kashani, Nima, Teleg, Erika, Asuncion, Ria, Wadhwa, Ankur, Wasyliw, Sanchea, Ryckborst, Karla, Newcommon, Nancy, Zimmel, Leslie, Bohn, Shelly, Doram, Craig, Ure, Ashley, Ashforth, Robert, Chow, Michael, Lloret, Mar, Kalashyan, Hayrapet, Jabs, Juline, Pickett, Gwynedd, Wade, Kevin, Weill, Alain, Legault, Catherine, Moore, Angela, Salmon, Kristiana, Khalil, Salma, Selchen, Daniel, Sarma, Dipanka, Bengzon Diestro, Jose Danilo, Sahlas, Demetrios, Deshmukh, Aviraj, Larrazabal, Ramiro, Mattia, Alicia, Taher, Noran, Heran, Manraj, Maclean, Genoveva, Flexman, Alana, Gayton, Yolanda, Boulos, Mark, Khosravani, Houman, Shah, Ruchir, Simpson, Cindy, Kaminsky, Ian, Kupniewski, Sonny, Choe, Hana, Jovin, Tudor, Jankowitz, Brian, Shah, Kavit, Walker, Gregory, Liff, Jeremy, Burgos, Adrian, Cutting, Shawna, Foley, Susan, Fuller, Lindsey, Watkins, Christina, Dellorso, Scott, Schemmel, Derek, Bhatt, Nirav, Bianchi, Nicolas, Al-Bayati, Alhamza, English, Stephen, Bedenk, Ann, Holloway, William, Kaddouh, Firas, Stretz, Hans Christoph, Jasak, Sara, Orgass, Hailey, Umekubo, Mark, Conrad, William, Abbott, Tara, Czerniak, Jennifer, Rai, Vivek, Rha, Joung-Ho, Tsoleridis, Jessica, Laffan, Aoife, Gordon, Patricia, Fearon, Patricia, McFarland, Margaret, Moreira, Tiago, Keselman, Boris, Schlemm, Eckhard, Otto, Dagmar, Haase, Kathrin, Sauer, Angela, Maus, Volker, Müller, Nicole, Potvin, Alphonse, Bermanis, Liat, Cuthbert, Sandra, Kohli, Yatika, Snoke, Kara

“…Nerinetide, an eicosapeptide that interferes with post-synaptic density protein 95, is a neuroprotectant that is effective in preclinical stroke models of…”
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Analysis of Workflow and Time to Treatment on Thrombectomy Outcome in the Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) Randomized, Controlled Trial by Menon, Bijoy K, Sajobi, Tolulope T, Zhang, Yukun, Rempel, Jeremy L, Shuaib, Ashfaq, Thornton, John, Williams, David, Roy, Daniel, Poppe, Alexandre Y, Jovin, Tudor G, Sapkota, Biggya, Baxter, Blaise W, Krings, Timo, Silver, Frank L, Frei, Donald F, Fanale, Christopher, Tampieri, Donatella, Teitelbaum, Jeanne, Lum, Cheemun, Dowlatshahi, Dar, Eesa, Muneer, Lowerison, Mark W, Kamal, Noreen R, Demchuk, Andrew M, Hill, Michael D, Goyal, Mayank

“…BACKGROUND—The Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) trial used innovative imaging and aggressive target time…”
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Exploring Reperfusion Following Endovascular Thrombectomy: A Proof of Concept Using Perfusion Angiography by Kosior, Jayme C., Buck, Brian, Wannamaker, Robert, Kate, Mahesh, Liapounova, Natalia A., Rempel, Jeremy L., Butcher, Kenneth

“…BACKGROUND AND PURPOSE—Cerebral perfusion in acute ischemic stroke patients is often assessed before endovascular thrombectomy (EVT), but rarely after…”
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Management of tandem occlusions in acute ischemic stroke - intracranial versus extracranial first and extracranial stenting versus angioplasty alone: a systematic review and meta-analysis by Wilson, Mitchell P, Murad, Mohammad H, Krings, Timo, Pereira, Vitor M, O'Kelly, Cian, Rempel, Jeremy, Hilditch, Christopher A, Brinjikji, Waleed

“…Optimal technical approaches of large-vessel anterior circulation acute ischemic strokes with concomitant extracranial internal carotid artery tandem…”
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Which Acute Ischemic Stroke Patients Are Fast Progressors?: Results From the ESCAPE Trial Control Arm by Ospel, Johanna M., Hill, Michael D., Kappelhof, Manon, Demchuk, Andrew M., Menon, Bijoy K., Mayank, Arnuv, Dowlatshahi, Dar, Frei, Don, Rempel, Jeremy L., Baxter, Blaise, Goyal, Mayank

“…Fast infarct progression in acute ischemic stroke has a severe impact on patient prognosis and benefit of endovascular thrombectomy. In this post hoc analysis…”
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How to Define Fast and Slow Progressors in Any-Type Occlusion Acute Ischemic Stroke by Nomani, Ali Z, Rempel, Jeremy L, Khan, Khurshid A, Shuaib, Ashfaq, Jickling, Glen C

“…The variable rate of infarct progression in acute ischemic stroke as assessed by various thresholds excludes a substantial proportion of patients due to time…”
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Prognostic Evaluation Based on Cortical Vein Score Difference in Stroke by Parthasarathy, Rajsrinivas, Kate, Mahesh, Rempel, Jeremy L., Liebeskind, David S., Jeerakathil, Thomas, Butcher, Kenneth S., Shuaib, Ashfaq

“…Multimodal imaging in acute ischemic stroke defines the extent of arterial collaterals, resultant penumbra, and associated infarct core, yet limitations…”
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Association of CT-Based Hypoperfusion Index With Ischemic Core Enlargement in Patients With Medium and Large Vessel Stroke by Nomani, Ali Z., Kamtchum Tatuene, Joseph, Rempel, Jeremy L., Jeerakathil, Thomas, Winship, Ian R., Khan, Khurshid A., Buck, Brian H., Shuaib, Ashfaq, Jickling, Glen C.

“…The rate of infarct core progression in patients with acute ischemic stroke is variable and affects outcome of reperfusion therapy. We evaluated the…”
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Infarcts in a New Territory: Insights From the ESCAPE-NA1 Trial by Singh, Nishita, Cimflova, Petra, Ospel, Johanna Maria, Kashani, Nima, Marko, Martha, Mayank, Arnuv, Nogueira, Raul G., McTaggart, Ryan A., Demchuk, Andrew M., Poppe, Alexandre Y., Rempel, Jeremy L., Field, Thalia S., Dowlatshahi, Dar, van Adel, Brian, Swartz, Richard H., Shah, Ruchir, Sauvageau, Eric, Puetz, Volker, Silver, Frank L., Campbell, Bruce, Chapot, René, Tymianski, Michael, Goyal, Mayank, Almekhlafi, Mohammed A., Hill, Michael D.

“…Infarct in a new territory (INT) is a known complication of endovascular stroke therapy. We assessed the incidence of INT, outcomes after INT, and the impact…”
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Endovascular Parent Vessel Occlusion Versus Flow Diversion in the Treatment of Large and Giant Aneurysms: A Randomized Comparison by Boisseau, William, Darsaut, Tim E., Fahed, Robert, Comby, Pierre Olivier, Drake, Brian, Lesiuk, Howard, Rempel, Jeremy L., O'Kelly, Cian J., Chow, Michael M.C., Iancu, Daniela E., Roy, Daniel, Weill, Alain, Klink, Ruby, Raymond, Jean

“…Parent vessel occlusion (PVO) is a time-honored treatment for unclippable or uncoilable intracranial aneurysms. Flow diversion (FD) is a recent endovascular…”
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Effect of Endovascular Thrombectomy for Acute Ischemic Stroke on Cognitive Outcomes: A Secondary Analysis of the ESCAPE Trial by Joundi, Raed A, Smith, Eric E, Mandzia, Jennifer, Ganesh, Aravind, Menon, Bijoy K, Rempel, Jeremy L, Thornton, John, Roy, Daniel, Jovin, Tudor G, Dowlatshahi, Dar, Frei, Donald F, Bharatha, Aditya, Poppe, Alexandre, Silver, Frank L, Shuaib, Ashfaq, Teitelbaum, Jeanne S, Williams, David, Bang, Oh Young, Sapkota, Biggya L, Burns, Paul, Choe, Hana, Heo, Jie-Hoe, Kelly, Michael E, Linares, Guillermo, Shankar, Jai J, Sohn, Sung-Il, Swartz, Richard H, Barber, Philip, Coutts, Shelagh B, Demchuk, Andrew, Goyal, Mayank, Hill, Michael D

“…The effect of endovascular therapy (EVT) for large vessel occlusion stroke on cognitive outcomes is not well understood. We evaluated the effect of EVT on…”
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Letter to the Editor: Pandemic (COVID-19) Proctoring for eCLIPs Neurointervention by O'Kelly, Cian, Rempel, Jeremy L., Diestro, Jose Danilo B., Marotta, Thomas R.

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Surgical or endovascular management of ruptured intracranial aneurysms: an agreement study by Darsaut, Tim E, Fahed, Robert, Macdonald, R Loch, Arthur, Adam S, Kalani, M Yashar S, Arikan, Fuat, Roy, Daniel, Weill, Alain, Bilocq, Alain, Rempel, Jeremy L, Chow, Michael M, Ashforth, Robert A, Findlay, J Max, Castro-Afonso, Luis H, Chagnon, Miguel, Gevry, Guylaine, Raymond, Jean

“…Ruptured intracranial aneurysms (RIAs) can be managed surgically or endovascularly. In this study, the authors aimed to measure the interobserver agreement in…”
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Discrepancy between post-treatment infarct volume and 90-day outcome in the ESCAPE randomized controlled trial by Ganesh, Aravind, Menon, Bijoy K, Assis, Zarina A, Demchuk, Andrew M, Al-Ajlan, Fahad S, Al-Mekhlafi, Mohammed A, Rempel, Jeremy L, Shuaib, Ashfaq, Baxter, Blaise W, Devlin, Thomas, Thornton, John, Williams, David, Poppe, Alexandre Y, Roy, Daniel, Krings, Timo, Casaubon, Leanne K, Kashani, Nima, Hill, Michael D, Goyal, Mayank

“…Background Some patients with ischemic stroke have poor outcomes despite small infarcts after endovascular thrombectomy, while others with large infarcts…”
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Comprehensive Aneurysm Management (CAM): An All-Inclusive Care Trial for Unruptured Intracranial Aneurysms by Darsaut, Tim E., Desal, Hubert, Cognard, Christophe, Januel, Anne-Christine, Bourcier, Romain, Boulouis, Grégoire, Shiva Shankar, Jai Jai, Findlay, J. Max, Rempel, Jeremy L., Fahed, Robert, Boccardi, Edoardo, Valvassori, Luca, Magro, Elsa, Gentric, Jean-Christophe, Bojanowski, Michel W., Chaalala, Chiraz, Iancu, Daniela, Roy, Daniel, Weill, Alain, Diouf, Ange, Gevry, Guylaine, Chagnon, Miguel, Raymond, Jean

“…In the absence of randomized evidence, the optimal management of patients with unruptured intracranial aneurysms (UIA) remains uncertain. Comprehensive…”
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Infarct in a New Territory After Treatment Administration in the ESCAPE Randomized Controlled Trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) by Ganesh, Aravind, Al-Ajlan, Fahad S, Sabiq, Farahna, Assis, Zarina, Rempel, Jeremy L, Butcher, Kenneth, Thornton, John, Kelly, Peter, Roy, Daniel, Poppe, Alexandre Y, Jovin, Tudor G, Devlin, Thomas, Baxter, Blaise W, Krings, Timo, Casaubon, Leanne K, Frei, Donald F, Choe, Hana, Tampieri, Donatella, Teitelbaum, Jeanne, Lum, Cheemun, Mandzia, Jennifer, Phillips, Stephen J, Bang, Oh Young, Almekhlafi, Mohammed A, Coutts, Shelagh B, Barber, Philip A, Sajobi, Tolulope, Demchuk, Andrew M, Eesa, Muneer, Hill, Michael D, Goyal, Mayank, Menon, Bijoy K

“…BACKGROUND AND PURPOSE—Infarct in a new previously unaffected territory (INT) is a potential complication of endovascular treatment. We applied a recently…”
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Treatment of wide-necked bifurcation aneurysms with the eCLIPs device: 5-year experience of a single center by Diestro, Jose Danilo Bengzon, Keough, Michael B, Ashforth, Robert A, Chow, Michael M, Rempel, Jeremy L, Marotta, Thomas R, O'Kelly, Cian

“…The endovascular clip system (eCLIPs) is a novel device with both neck bridging and flow-diversion properties that make it suitable for the treatment of…”
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Time From Hospital Arrival Until Endovascular Thrombectomy and Patient-Reported Outcomes in Acute Ischemic Stroke by Joundi, Raed A, Smith, Eric E, Ganesh, Aravind, Nogueira, Raul G, McTaggart, Ryan A, Demchuk, Andrew M, Poppe, Alexandre Y, Rempel, Jeremy L, Field, Thalia S, Dowlatshahi, Dar, Sahlas, Jim, Swartz, Richard, Shah, Ruchir, Sauvageau, Eric, Puetz, Volker, Silver, Frank L, Campbell, Bruce, Chapot, René, Tymianski, Michael, Goyal, Mayank, Hill, Michael D

“…The time-benefit association of endovascular thrombectomy (EVT) in ischemic stroke with patient-reported outcomes is unknown. To assess the time-dependent…”
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Computed Tomographic Perfusion Predicts Poor Outcomes in a Randomized Trial of Endovascular Therapy by Wannamaker, Robert, Guinand, Taurian, Menon, Bijoy K, Demchuk, Andrew, Goyal, Mayank, Frei, Donald, Bharatha, Aditya, Jovin, Tudor G, Shankar, Jai, Krings, Timo, Baxter, Blaise, Holmstedt, Christine, Swartz, Richard, Dowlatshahi, Dar, Chan, Richard, Tampieri, Donatella, Choe, Hana, Burns, Paul, Gentile, Nina, Rempel, Jeremy, Shuaib, Ashfaq, Buck, Brian, Bivard, Andrew, Hill, Michael, Butcher, Kenneth

“…BACKGROUND AND PURPOSE—In the ESCAPE trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion with Emphasis on Minimizing CT to…”
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Intra-Arterial Therapy and Post-Treatment Infarct Volumes: Insights From the ESCAPE Randomized Controlled Trial by Al-Ajlan, Fahad S, Goyal, Mayank, Demchuk, Andrew M, Minhas, Priyanka, Sabiq, Farahna, Assis, Zarina, Willinsky, Robert, Montanera, Walter J, Rempel, Jeremy L, Shuaib, Ashfaq, Thornton, John, Williams, David, Roy, Daniel, Poppe, Alexandre Y, Jovin, Tudor G, Sapkota, Biggya L, Baxter, Blaise W, Krings, Timo, Silver, Frank L, Frei, Donald F, Fanale, Christopher, Tampieri, Donatella, Teitelbaum, Jeanne, Lum, Cheemun, Dowlatshahi, Dar, Shankar, Jai J, Barber, Philip A, Hill, Michael D, Menon, Bijoy K

“…BACKGROUND AND PURPOSE—The goal of reperfusion therapy in acute ischemic stroke is to limit brain infarction. The objective of this study was to investigate…”
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