Search Results - "Remes, Anne M."
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Cardiovascular brain impulses in Alzheimer's disease
Published in Brain (London, England : 1878) (17-08-2021)“…Accumulation of amyloid-β is a key neuropathological feature in brain of Alzheimer's disease patients. Alterations in cerebral haemodynamics, such as arterial…”
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2
Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
Published in Nature (London) (09-02-2012)“…Induced pluripotent stem cells are shown to be useful for studying phenotypes relevant to familial and sporadic Alzheimer’s disease, even though it can take…”
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CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2019)“…ObjectiveTo examine the differential diagnostic significance of cerebrospinal fluid (CSF) biomarkers reflecting Alzheimer’s disease-related amyloid β (Aβ)…”
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Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders
Published in Journal of neurology (01-01-2020)“…Due to the significant clinical overlap between frontotemporal lobar degeneration (FTLD) spectrum disorders and late-onset primary psychiatric disorders (PPD),…”
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The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies
Published in Scientific reports (09-12-2020)“…Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer’s disease (AD) symptoms could improve disease detection and enable timely…”
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Lifetime antipsychotic medication and cognitive performance in schizophrenia at age 43 years in a general population birth cohort
Published in Psychiatry research (01-01-2017)“…Abstract This naturalistic study analysed the association between cumulative lifetime antipsychotic dose and cognition in schizophrenia after an average of…”
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C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction
Published in Neurobiology of disease (01-01-2022)“…Frontotemporal lobar degeneration (FTLD) comprises a heterogenous group of progressive neurodegenerative syndromes. To date, no validated biomarkers or…”
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Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease
Published in Dementia and geriatric cognitive disorders (01-09-2020)“…Behavioral variant frontotemporal dementia (bvFTD) is the most common clinical subtype of frontotemporal lobar degeneration. bvFTD is often characterized by…”
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The Phenotype of the C9ORF72 Expansion Carriers According to Revised Criteria for bvFTD
Published in PloS one (06-07-2015)“…The C9ORF72 expansion is one of the most common genetic etiologies observed with behavioural variant frontotemporal dementia (bvFTD). Revised diagnostic…”
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Differential diagnosis of neurodegenerative diseases using structural MRI data
Published in NeuroImage clinical (01-01-2016)“…Different neurodegenerative diseases can cause memory disorders and other cognitive impairments. The early detection and the stratification of patients…”
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Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS
Published in Frontiers in neuroscience (15-05-2019)“…Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases with a complex, but often overlapping, genetic…”
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The Association Between Distinct Frontal Brain Volumes and Behavioral Symptoms in Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia
Published in Frontiers in neurology (03-10-2019)“…Our aim was to investigate the association between behavioral symptoms of agitation, disinhibition, irritability, elation, and aberrant motor behavior to…”
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Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients
Published in Fluids and barriers of the CNS (05-02-2022)“…The relationship between cerebrospinal fluid (CSF) biomarkers and the clinical features of idiopathic normal pressure hydrocephalus (iNPH) has been…”
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Feasibility of radiological markers in idiopathic normal pressure hydrocephalus
Published in Acta neurochirurgica (01-10-2015)“…Background Various radiological markers have been proposed for diagnostics in idiopathic normal pressure hydrocephalus (iNPH). We examined the usefulness of…”
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Prevalence of Schizophrenia in Idiopathic Normal Pressure Hydrocephalus
Published in Neurosurgery (01-04-2019)“…Abstract BACKGROUND Idiopathic normal pressure hydrocephalus (iNPH) is a progressive and potentially treatable neurodegenerative disease affecting elderly…”
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Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers
Published in Frontiers in neuroscience (21-06-2019)“…Despite the current diagnostic criteria, early diagnostics of behavioral variant of frontotemporal dementia (bvFTD) has remained challenging. Patients with…”
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Detecting frontotemporal dementia syndromes using MRI biomarkers
Published in NeuroImage clinical (01-01-2019)“…Diagnosing frontotemporal dementia may be challenging. New methods for analysis of regional brain atrophy patterns on magnetic resonance imaging (MRI) could…”
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Prevalence of C9ORF72 Expansion in a Large Series of Patients with Idiopathic Normal-Pressure Hydrocephalus
Published in Dementia and geriatric cognitive disorders (01-05-2019)“…The C9ORF72 expansion is known to cause frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). We aim to identify the prevalence of…”
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Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy
Published in PloS one (01-01-2020)“…An accurate and timely diagnosis for Alzheimer's disease (AD) is important, both for care and research. The current diagnostic criteria allow the use of CSF…”
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Familial idiopathic normal pressure hydrocephalus
Published in Journal of the neurological sciences (15-09-2016)“…Abstract Idiopathic normal pressure hydrocephalus (iNPH) is a late-onset surgically alleviated, progressive disease. We characterize a potential familial…”
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