Search Results - "Remacle, A G"

Furin regulates the intracellular activation and the uptake rate of cell surface-associated MT1-MMP by REMADE, A. G, ROZANOV, D. V, FUGERE, M, DAY, R, STRONGIN, A. Y

“…Invasion-promoting membrane type-1 matrix metalloproteinase (MT1-MMP) functions in cancer cells as an oncogene and as a mediator of proteolytic events on the…”
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Assay of matrix metalloproteinases types 1, 2, 3 and 9 in breast cancer by REMACLE, A. G, NOËL, A, DUGGAN, C, MCDERMOTT, E, O'HIGGINS, N, FOIDART, J. M, DUFFY, M. J

“…Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases implicated in cancer invasion and metastasis. Gelatin zymography was performed on 84 human…”
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A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1–MMP by Shiryaev, S A, Remacle, A G, Golubkov, V S, Ingvarsen, S, Porse, A, Behrendt, N, Cieplak, P, Strongin, A Y

“…Matrix metalloproteinases (MMPs) and, especially membrane type 1 (MT1)-MMP/MMP-14, are promising drug targets in malignancies. In contrast with multiple…”
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Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase by Emonard, H P, Remacle, A G, Noël, A C, Grimaud, J A, Stetler-Stevenson, W G, Foidart, J M

“…We have studied the capacity of two human breast adenocarcinoma cells, MDA-MB231 and MCF-7, to bind exogenous M(r) 72,000 type IV collagenase by both…”
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Expression of Concern: Distinct Interactions with Cellular E-Cadherin of the Two Virulent Metalloproteinases Encoded by a Bacteroides fragilis Pathogenicity Island

“…[...]of these inactivating mutations, Ala substitutes for the essential active site Glu residue. The FRA3 and FRA3-E349A panels in Fig 5B are redacted as they…”
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Timp‐2 binding with cellular MT1‐MMP stimulates invasion‐promoting MEK/ERK signaling in cancer cells by Sounni, Nor Eddine, Rozanov, Dmitri V., Remacle, Albert G., Golubkov, Vladislav S., Noel, Agnes, Strongin, Alex Y.

“…Both invasion‐promoting MT1‐MMP and its physiological inhibitorTIMP‐2 play a significant role in tumorigenesis and are identified in the most aggressive…”
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Purification of Progelatinases A and B by Continuous-Elution Electrophoresis by Remacle, A.G., Baramova, E.N., Weidle, U.H., Krell, H.W., Foidart, J.M.

“…Progelatinases A and B were purified from HT1080-conditioned culture medium using a continuous-elution electrophoresis. Initially cell culture medium was…”
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Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cells by Radichev, Ilian A, Remacle, Albert G, Sounni, Nor Eddine, Shiryaev, Sergey A, Rozanov, Dmitri V, Zhu, Wenhong, Golubkova, Natalya V, Postnova, Tatiana I, Golubkov, Vladislav S, Strongin, Alex Y

“…Invasion-promoting MT1-MMP (membrane type-1 matrix metalloproteinase) is a key element in cell migration processes. To identify the proteins that interact and…”
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transmembrane domain is essential for the microtubular trafficking of membrane type-1 matrix metalloproteinase (MT1-MMP) by Remacle, Albert G, Rozanov, Dmitri V, Baciu, Peter C, Chekanov, Alexei V, Golubkov, Vladislav S, Strongin, Alex Y

“…Membrane type-1 matrix metalloproteinase (MT1-MMP) degrades the extracellular matrix, initiates the activation pathway of soluble MMPs and regulates the…”
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British Journal of Cancer by Remacle, A. G, Noël, Agnès, Duggan, C, McDermott, E, O'Higgins, N, Foidart, Jean-Michel, Duffy, M. J

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Both PA63 and PA83 are endocytosed within an anthrax protective antigen mixed heptamer: A putative mechanism to overcome a furin deficiency by Chekanov, Alexei V., Remacle, Albert G., Golubkov, Vladislav S., Akatov, Vladimir S., Sikora, Sergey, Savinov, Alexei Y., Fugere, Martin, Day, Robert, Rozanov, Dmitri V., Strongin, Alex Y.

“…Anthrax toxin consists of protective antigen (PA), and lethal (LF) and edema (EF) factors. A 83 kDa PA monomer (PA83) precursor binds to the cell receptor…”
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Tumor cell surface-associated binding site for the Mr 72,000 type IV by EMONARD, H. P, REMACLE, A. G, NOËL, A. C, GRIMAUD, J.-A, STETLER-STEVENSON, W. G, FOIDART, J.-M

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Tumor cell surface-associated binding site for the M sub(r) 72,000 type IV collagenase by Emonard, H P, Remacle, A G, Noel, A C, Grimaud, J-A, Stetler-Stevenson, W G, Foidart, J-M

“…We have studied the capacity of two human breast adenocarcinoma cells, MDA-MB231 and MCF-7, to bind exogenous M sub(r) 72,000 type IV collagenase by both…”
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