Search Results - "Rekasi, Z"

Accumulation of rat pineal serotonin N-acetyltransferase mRNA induced by pituitary adenylate cyclase activating polypeptide and vasoactive intestinal peptide in vitro by Rekasi, Z, Czompoly, T

“…In mammals, pineal melatonin secretion is under the control of adrenergic and peptidergic inputs regulating serotonin N-acetyltransferase (arylalkylamine…”
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Synthesis and Biological Activities of Highly Potent Antagonists of Growth Hormone-Releasing Hormone by Zarandi, M., Horvath, J. E., Halmos, G., Pinski, J., Nagy, A., Groot, K., Rekasi, Z., Schally, A. V.

“…In the search for antagonists of human growth hormone-releasing hormone (hGHRH) with high activity, 22 analogs were synthesized by solid-phase methods,…”
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Analogues of Luteinizing Hormone-Releasing Hormone Containing Cytotoxic Groups by Janaky, T., Juhasz, A., Bajusz, S., Csernus, V., Srkalovic, G., Bokser, L., Milovanovic, S., Redding, T. W., Rekasi, Z., Nagy, A., Schally, A. V.

“…In an attempt to produce better cytotoxic analogues, chemotherapeutic antineoplastic radicals including an alkylating nitrogen mustard derivative of…”
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Targeted Cytotoxic Analogue of Luteinizing Hormone-Releasing Hormone (LH-RH) Only Transiently Decreases the Gene Expression of Pituitary Receptors for LH-RH by Kovacs, M., Schally, A. V., Csernus, B., Busto, R., Rekasi, Z., Nagy, A.

“…A cytotoxic analogue of LH‐RH, AN‐207, consisting of 2‐pyrrolinodoxorubicin (AN‐201) linked to carrier [D‐Lys6]LH‐RH, was developed for targeted therapy of…”
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Short-Chain Analogs of Luteinizing Hormone-Releasing Hormone Containing Cytotoxic Moieties by Janaky, T., Juhasz, A., Rekasi, Z., Serfozo, P., Pinski, J., Bokser, L., Srkalovic, G., Milovanovic, S., Redding, T. W., Halmos, G., Nagy, A., Schally, A. B.

“…Five hexapeptide and heptapeptide analogs of luteinizing hormone-releasing hormone (LH-RH) were synthesized for use as carriers for cytotoxic compounds. These…”
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A Method for Evaluation of Activity of Antagonistic Analogs of Growth Hormone-Releasing Hormone in a Superfusion System by Rekasi, Zoltan, Schally, Andrew V.

“…Antagonistic analogs of growth hormone-releasing hormone (GHRH) are being synthesized in our laboratory for various clinical applications, including treatment…”
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LH-RH analogue carrying a cytotoxic radical is internalized by rat pituitary cells in vitro by Szöke, B, Horváth, J, Halmos, G, Rékási, Z, Groot, K, Nagy, A, Schally, A V

“…The binding and internalization of a cytotoxic analogue of luteinizing hormone-releasing hormone (LH-RH), T-98 (agonist [D-Lys6]LH-RH linked to…”
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Synthesis and Biological Evaluation of Antagonists of Growth Hormone-Releasing Hormone with High and Protracted in vivo Activities by Varga, Jozsef L., Schally, Andrew V., Csernus, Valer J., Zarandi, Marta, Halmos, Gabor, Groot, Kate, Rekasi, Zoltan

“…Some antagonists of human growth hormone-releasing hormone (hGH-RH) synthesized previously were shown to inhibit in vivo proliferation of various human cancers…”
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Effect of luteinizing hormone-releasing hormone analogs containing cytotoxic radicals on the function of rat pituitary cells: tests in a long term superfusion system by Rékási, Z, Szöke, B, Nagy, A, Groot, K, Rékási, E S, Schally, A V

“…A novel class of targeted chemotherapeutic agents based on cytotoxic compounds linked to LHRH analogs was tested in a long term superfusion system in order to…”
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Isolation and Sequencing of cDNAs for Splice Variants of Growth Hormone-Releasing Hormone Receptors from Human Cancers by Rekasi, Zoltan, Czompoly, Tamas, Schally, Andrew V., Halmos, Gabor

“…The proliferation of various tumors is inhibited by the antagonists of growth hormone-releasing hormone (GHRH) in vitro and in vivo, but the receptors…”
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Antagonists of growth hormone-releasing hormone arrest the growth of MDA-MB-468 estrogen-independent human breast cancers in nude mice by Kahán, Z, Varga, J L, Schally, A V, Rékási, Z, Armatis, P, Chatzistamou, L, Czömpöly, T, Halmos, G

“…Since antagonists of growth hormone-releasing hormone (GH-RH) inhibit proliferation of various tumors, in this study we investigated the effects of GH-RH…”
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Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variants in Human Prostate Cancer by Halmos, Gabor, Schally, Andrew V., Czompoly, Tamas, Krupa, Magdalena, Varga, Jozsef L., Rekasi, Zoltan

“…Antagonists of GHRH inhibit the growth of various human tumors, including prostate cancer, but the tumoral receptors mediating the antiproliferative effect of…”
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Peptide analogs in the therapy of prostate cancer by Schally, Andrew V., Comaru-Schally, Ana Maria, Plonowski, Artur, Nagy, Attila, Halmos, Gabor, Rekasi, Zoltan

“…The use of peptide analogs in the therapy of prostate cancer is reviewed. The preferred primary treatment of advanced androgen‐dependent prostate cancer is…”
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Human Renal Cell Carcinoma Expresses Distinct Binding Sites for Growth Hormone-Releasing Hormone by Halmos, Gabor, Schally, Andrew V., Varga, Jozsef L., Plonowski, Artur, Rekasi, Zoltan, Czompoly, Tamas

“…Antagonists of growth hormone-releasing hormone (GHRH) inhibit the proliferation of various human cancers in vitro and in vivo by mechanisms that include…”
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Increased Activity of Antagonists of Growth Hormone-Releasing Hormone Substituted at Positions 8, 9, and 10 by Varga, Jozsef L., Schally, Andrew V., Horvath, Judit E., Kovacs, Magdolna, Halmos, Gabor, Groot, Kate, Toller, Gabor L., Rekasi, Zoltan, Zarandi, Marta

“…Antagonists of human growth hormone-releasing hormone (hGHRH) with increased potency and improved enzymatic and chemical stability are needed for potential…”
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Antagonist of Growth Hormone-Releasing Hormone Induces Apoptosis in LNCaP Human Prostate Cancer Cells through a Ca2+-Dependent Pathway by Rekasi, Zoltan, Czompoly, Tamas, Schally, Andrew V., Boldizsar, Ferenc, Varga, Jozsef L., Zarandi, Marta, Berki, Timea, Horvath, Reka A., Nemeth, Peter

“…Antagonists of growth hormone-releasing hormone (GHRH) exert antiproliferative effects directly on cancer cells, which are mediated by the tumoral GHRH…”
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Differences in hormone release patterns from the anterior pituitary and the pineal gland by Csernus, V J, Rékási, Z, Mess, B

“…Patterns of hormone release from peptide- and monoamine-hormone secreting cells were compared. LH, GH and PRL secretion from rat anterior pituitary cells and…”
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Antagonists of Growth Hormone-Releasing Hormone and Vasoactive Intestinal Peptide Inhibit Tumor Proliferation by Different Mechanisms: Evidence from in Vitro Studies on Human Prostatic and Pancreatic Cancers by Rekasi, Zoltan, Varga, Jozsef L., Schally, Andrew V., Halmos, Gabor, Armatis, Patricia, Groot, Kate, Czompoly, Tamas

“…Abstract Antagonists of GH-releasing hormone (GHRH) and vasoactive intestinal peptide (VIP) inhibit the proliferation of various tumors in vitro and in vivo,…”
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Luteinizing Hormone-Releasing Hormone (LH-RH) Antagonist Cetrorelix Down-Regulates the mRNA Expression of Pituitary Receptors for LH-RH by Counteracting the Stimulatory Effect of Endogenous LH-RH by Kovacs, Magdolna, Schally, Andrew V., Csernus, Balazs, Rekasi, Zoltan

“…The mechanisms through which LH-RH antagonists suppress gonadotroph functions and LH-RH receptor (LH-RH-R) production are incompletely understood. To elucidate…”
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Suppression of serotonin N-acetyltransferase transcription and melatonin secretion from chicken pinealocytes transfected with Bmal1 antisense oligonucleotides containing locked nucleic acid in superfusion system by Rekasi, Zoltan, Horvath, Reka A., Klausz, Barbara, Nagy, Eniko, Toller, Gabor L.

“…In birds, rhythmic changes in pineal serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, Aanat) transcripts are controlled by an oscillator…”
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