Search Results - "Rejeeth, Chandrababu"
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Label-free designed nanomaterials enrichment and separation techniques for phosphoproteomics based on mass spectrometry
Published in Frontiers in nanotechnology (01-12-2022)“…The surface chemical characteristics of nanomaterials have a substantial impact on the affinity probe used to enrich proteins and peptides for MALDI-MS…”
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Extraction, detection, and profiling of serum biomarkers using designed Fe3O4@SiO2@HA core-shell particles
Published in Nano research (2018)“…Serum biomarkers in the form of proteins (e.g. cluster of differentiation-44 (CD44)) have been demonstrated to have high clinical sensitivity and specificity…”
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Recent advcances on plant-based bioengineered nanoparticles using secondary metabolites and their potential in lung cancer management
Published in Journal of future foods (01-03-2025)“…As modern technology evolves, researchers are attempting to discover novel strategies for controlling deadly lung cancer. The use of secondary metabolites from…”
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p53 gene therapy of human breast carcinoma: using a transferrin-modified silica nanoparticles
Published in Breast cancer (Tokyo, Japan) (01-01-2016)“…Background Nanoparticles have an enormous potential for development in biomedical applications, such as gene or drug delivery. In our study, we examined the…”
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Nanostructured pH-responsive biocompatible chitosan coated copper oxide nanoparticles: A polymeric smart intracellular delivery system for doxorubicin in breast cancer cells
Published in Arabian journal of chemistry (01-01-2020)“…In this study, we report a novel feasible single step reduction method for the active synthesis of biocompatible chitosan coated copper oxide nanoparticles…”
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Multifunctional nanoparticles for trimodal photodynamic therapy-mediated photothermal and chemotherapeutic effects
Published in Photodiagnosis and photodynamic therapy (01-09-2018)“…pH-switchable integrated nanodelivery of Carboplatin/ICG to cancer for an efficient tumor ablation for folate receptor-targeted delivery, in particularly,…”
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Biofabricated selenium nanoparticles mediated from Goniothalamus wightii gains biomedical applications and photocatalytic degrading ability
Published in Journal of King Saud University. Science (01-11-2022)“…Selenium nanoparticles (SeNPs) have attracted recently in different biomedical applications due to its unique role of metabolic function prevents cellular…”
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Optimal immobilization of Trichoderma asperellum laccase on polymer coated Fe3O4@SiO2 nanoparticles for enhanced biohydrogen production from delignified lignocellulosic biomass
Published in Fuel (Guildford) (01-08-2020)“…•Trichoderma asperellum laccase immobilized on chitosan coated Fe3O4@SiO2 NPs.•Process parameters for laccase immobilization on NPs were optimized by…”
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Label-Free Electrochemical Sensor for CD44 by Ligand-Protein Interaction
Published in Analytical chemistry (Washington) (04-06-2019)“…Detection of biomarkers in biosystems plays a key role in advanced biodiagnostics for research and clinical use. Design of new analytical platforms is…”
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Novel luminescent silica nanoparticles (LSN): p53 gene delivery system in breast cancer in vitro and in vivo
Published in Journal of pharmacy and pharmacology (01-03-2016)“…Objectives Mutations in the p53 tumor suppressor gene are one among the most common genetic abnormalities to be described in breast cancer. However, there are…”
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Multifunctional HER2-Antibody Conjugated Polymeric Nanocarrier-Based Drug Delivery System for Multi-Drug-Resistant Breast Cancer Therapy
Published in ACS applied materials & interfaces (14-05-2014)“…Nanotechnology-based medical approaches have made tremendous potential for enhancing the treatment efficacy with minimal doses of chemotherapeutic drugs…”
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Comparison of two silica based nonviral gene therapy vectors for breast carcinoma: evaluation of the p53 delivery system in Balb/c mice
Published in Artificial cells, nanomedicine, and biotechnology (03-04-2017)“…Silica nanoparticles as a nonviral vector for in vivo gene therapy neither surface functionalized SiNp1 is neither "a cationic ion" nor a surface…”
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A novel device for swift and efficient CD44 protein digestion of pipette tips in human serum
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-07-2023)“…•Increased number of identified CD44 peptied compared to the 12 h insolation digestion.•Enhanced proteolytic performance towards a complex of proteins with…”
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HER2 Targeted Breast Cancer Therapy with Switchable “Off/On” Multifunctional “Smart” Magnetic Polymer Core–Shell Nanocomposites
Published in ACS applied materials & interfaces (27-01-2016)“…Multifunctional magnetic polymer nanocombinations are gaining importance in cancer nanotheranostics due to their safety and their potential in delivering…”
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Exploring status of emergency drugs and vaccine development in Covid-19 pandemic: an update
Published in Virusdisease (01-06-2021)“…COVID-19 outburst initiated from the city of Wuhan in China in December 2019 and has been declared as a public health emergency of international concern. This…”
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Green synthesis of silver nanoparticles from corn cob aqueous extract for colorimetric cysteine detection in serum simulated with cysteine samples
Published in Optik (Stuttgart) (01-08-2022)“…In this study described a green approach for synthesizing silver nanoparticles (AgNPs) with corncob acting as a reducing and stabilizing agent to rapidly…”
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A Novel Azathioprine Polysaccharide Nanoparticle Enhances the Efficacy of Systemic Lupus Erythematosus Therapy
Published in Journal of pharmaceutical innovation (01-12-2023)“…Systemic lupus erythematosus (SLE) patients will suffer from some level of discomfort as the disease progresses due to involvement with the respiratory system…”
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Enhanced Drug Delivery, G2/M Cell Cycle Arrest and Apoptosis Induced by Myricetin-Loaded Nanogels in MCF-7 Breast Cancer Cells
Published in Journal of cluster science (01-02-2024)“…As direct chemotherapy drugs are still unable to target the tumor, they frequently have systemic adverse effects and inadequate therapeutic efficacy if used to…”
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Novel Green Silver Nanoparticles as Matrix in the Detection of Small Molecules Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-MS)
Published in Journal of pharmaceutical innovation (01-12-2021)“…Purpose The number of studies utilizing the matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has significantly increased over the past…”
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Design of Bio-Graphene-Based Multifunctional Nanocomposites Exhibits Intracellular Drug Delivery in Cervical Cancer Treatment
Published in ACS applied bio materials (20-06-2022)“…The advent of bio-nanotechnology has revolutionized nanodrug delivery by improving drug efficacy and safety. Nevertheless, acceptable carriers for therapeutic…”
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