Search Results - "Reitsma, Sofia"

Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors by Caldwell, Charles, Rottman, James B., Paces, Will, Bueche, Elizabeth, Reitsma, Sofia, Gibb, Joseph, Adisetiyo, Vitria, Haas, Michael S., Heath, Heidi, Newman, Walter, Baum, Jason, Gianani, Roberto, Kagey, Michael H.

“…Dickkopf-1 (DKK1) is a secreted modulator of Wnt signaling that is frequently overexpressed in tumors and associated with poor clinical outcomes. DKN-01 is a…”
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Abstract 3137: Characterizing heterogeneity of CD8 inflammation in biopsied tumor tissues using novel image analysis techniques by Caldwell, Charles William, Paces, Will, Reitsma, Sofia, Brueckner, Christopher, Lee-Hoeflich, Si T., Gianani, Roberto

“…Abstract Analyzing images of tissue sections stained with biomarker-specific indicators can generate quantitative, cell-specific expression data rather than…”
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Abstract 433: Clinical validation of a Dickkopf-1 (DKK1) chromogenic in-situ hybridization (CISH) assay for manual and image-analysis assisted pathologist interpretation by Caldwell, Charles, Kagey, Mike, Reitsma, Sofia, Paces, Will, Bueche, Elizabeth, Adisetiyo, Vitria, Gianani, Roberto

“…Abstract Dickkopf-1 (DKK1) is a secreted modulator of Wnt signaling that is frequently overexpressed in tumors and associated with a poor prognosis. In this…”
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Abstract 1801: Development of a comprehensive biomarker strategy to support phase 1 clinical trial of SRK-181 the latent TGFβ1 inhibitor by Brueckner, Christopher, Faucette, Ryan, Caldwell, Charles, Reitsma, Sofia, Wawersik, Stefan, Kalra, Ashish, Gan, Lu, Lee-Hoeflich, Si Tuen

“…Abstract TGFβ signaling appears to be a key mediator of primary resistance to programmed cell death protein (PD-1) pathway blockade. SRK-181 is an…”
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