Search Results - "Reiter, Katherine H"

Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector by Akturk, Anil, Wasilko, David J., Wu, Xiaochun, Liu, Yao, Zhang, Yong, Qiu, Jiazhang, Luo, Zhao-Qing, Reiter, Katherine H., Brzovic, Peter S., Klevit, Rachel E., Mao, Yuxin

“…Ubiquitination is a post-translational modification that regulates many cellular processes in eukaryotes 1 – 4 . The conventional ubiquitination cascade…”
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Characterization of RING-Between-RING E3 Ubiquitin Transfer Mechanisms by Reiter, Katherine H, Klevit, Rachel E

“…Protein ubiquitination is an essential posttranslational modification that regulates nearly all cellular processes. E3 ligases catalyze the final transfer of…”
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Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1 by Dove, Katja K., Olszewski, Jennifer L., Martino, Luigi, Duda, David M., Wu, Xiaoli S., Miller, Darcie J., Reiter, Katherine H., Rittinger, Katrin, Schulman, Brenda A., Klevit, Rachel E.

“…RING-between-RING (RBR) E3s contain RING1 domains that are structurally similar yet mechanistically distinct from canonical RING domains. Both types of E3 bind…”
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Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain by Reiter, Katherine H., Zelter, Alex, Janowska, Maria K., Riffle, Michael, Shulman, Nicholas, MacLean, Brendan X., Tamura, Kaipo, Chambers, Matthew C., MacCoss, Michael J., Davis, Trisha N., Guttman, Miklos, Brzovic, Peter S., Klevit, Rachel E.

“…RING-between-RING (RBR) E3 ligases mediate ubiquitin transfer through an obligate E3-ubiquitin thioester intermediate prior to substrate ubiquitination…”
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Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate in Caenorhabditis elegans development by Dove, Katja K., Kemp, Hilary A., Di Bona, Kristin R., Reiter, Katherine H., Milburn, Luke J., Camacho, David, Fay, David S., Miller, Dana L., Klevit, Rachel E.

“…Ubiquitination, the crucial posttranslational modification that regulates the eukaryotic proteome, is carried out by a trio of enzymes, known as E1 [ubiquitin…”
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Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems by Reiter, Katherine H., Ramachandran, Anita, Xia, Xue, Boucher, Lauren E., Bosch, Jürgen, Matunis, Michael J.

“…Protein modification by small ubiquitin-related modifiers (SUMOs) is essential and conserved in the malaria parasite, Plasmodium falciparum. We have previously…”
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Detection of SUMOylation in Plasmodium falciparum by Reiter, Katherine H, Matunis, Michael J

“…Reversible protein modification by small ubiquitin-related modifiers (SUMOs) regulates many cellular processes, including transcription, protein quality…”
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E2-mediated Small Ubiquitin-like Modifier (SUMO) Modification of Thymine DNA Glycosylase Is Efficient but Not Selective for the Enzyme-Product Complex by Coey, Christopher T., Fitzgerald, Megan E., Maiti, Atanu, Reiter, Katherine H., Guzzo, Catherine M., Matunis, Michael J., Drohat, Alexander C.

“…Thymine DNA glycosylase (TDG) initiates the repair of G·T mismatches that arise by deamination of 5-methylcytosine (mC), and it excises 5-formylcytosine and…”
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Structural Studies of HHARI/UbcH7~Ub Reveal Unique E2~Ub Conformational Restriction by RBR RING1 by Dove, Katja K., Olszewski, Jennifer L., Martino, Luigi, Duda, David M., Wu, Xiaoli S., Miller, Darcie J., Reiter, Katherine H., Rittinger, Katrin, Schulman, Brenda A., Klevit, Rachel E.

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