Search Results - "Reiter, Dirk M"
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The sweet spot: defining virus–sialic acid interactions
Published in Nature reviews. Microbiology (01-11-2014)“…Key Points Many viruses engage sialylated glycans to bind to and infect cells. Sialic acid-binding viruses include influenza virus, reovirus, adenovirus and…”
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The Role of Functional Amyloids in Bacterial Virulence
Published in Journal of molecular biology (12-10-2018)“…Amyloid fibrils are best known as a product of human and animal protein misfolding disorders, where amyloid formation is associated with cytotoxicity and…”
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The GM2 glycan serves as a functional coreceptor for serotype 1 reovirus
Published in PLoS pathogens (01-12-2012)“…Viral attachment to target cells is the first step in infection and also serves as a determinant of tropism. Like many viruses, mammalian reoviruses bind with…”
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4
Crystal structure of reovirus attachment protein σ1 in complex with sialylated oligosaccharides
Published in PLoS pathogens (01-08-2011)“…Many viruses attach to target cells by binding to cell-surface glycans. To gain a better understanding of strategies used by viruses to engage carbohydrate…”
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5
Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions
Published in PLoS pathogens (01-08-2017)“…Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) and Knob-associated Histidine-rich Protein (KAHRP) are directly linked to malaria pathology…”
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6
Utilization of Sialylated Glycans as Coreceptors Enhances the Neurovirulence of Serotype 3 Reovirus
Published in Journal of Virology (01-12-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An Arginine Switch in the Species B Adenovirus Knob Determines High-Affinity Engagement of Cellular Receptor CD46
Published in Journal of Virology (2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
Optimum Length and Flexibility of Reovirus Attachment Protein σ1 Are Required for Efficient Viral Infection
Published in Journal of Virology (01-10-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function
Published in Molecular biology of the cell (15-09-2013)“…Intestinal barrier function is regulated by epithelial tight junctions (TJs), structures that control paracellular permeability. Junctional adhesion molecule-A…”
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10
Adenovirus type 11 binding alters the conformation of its receptor CD46
Published in Nature structural & molecular biology (01-02-2007)“…Adenoviruses (Ads) are important human pathogens and valuable gene delivery vehicles. We report here the crystal structure of the species B Ad11 knob complexed…”
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11
Crystal Structure of Reovirus Attachment Protein [sigma]1 in Complex with Sialylated Oligosaccharides
Published in PLoS pathogens (01-08-2011)“…Many viruses attach to target cells by binding to cell-surface glycans. To gain a better understanding of strategies used by viruses to engage carbohydrate…”
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