Search Results - "Reisman, Sarah E"

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions by Poremba, Kelsey E, Dibrell, Sara E, Reisman, Sarah E

“…Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to join two electrophiles. These reactions have proven particularly useful…”
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Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds by Cherney, Alan H, Kadunce, Nathaniel T, Reisman, Sarah E

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Nickel-Catalyzed Asymmetric Reductive Cross-Coupling Between Vinyl and Benzyl Electrophiles by Cherney, Alan H, Reisman, Sarah E

“…A Ni-catalyzed asymmetric reductive cross-coupling between vinyl bromides and benzyl chlorides has been developed. This method provides direct access to…”
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A 16-step synthesis of the isoryanodane diterpene (+)-perseanol by Han, Arthur, Tao, Yujia, Reisman, Sarah E.

“…(+)-Perseanol is an isoryanodane diterpene that is isolated from the tropical shrub Persea indica 1 and has potent antifeedant and insecticidal properties. It…”
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Recent Developments in the Catalytic, Asymmetric Construction of Pyrroloindolines Bearing All-Carbon Quaternary Stereocenters by Repka, Lindsay M, Reisman, Sarah E

“…Pyrroloindoline alkaloids constitute a large family of natural products that has inspired the development of an impressive array of new reactions to prepare…”
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Synthesis of Enantioenriched Allylic Silanes via Nickel-Catalyzed Reductive Cross-Coupling by Hofstra, Julie L, Cherney, Alan H, Ordner, Ciara M, Reisman, Sarah E

“…An asymmetric Ni-catalyzed reductive cross-coupling has been developed to prepare enantio­enriched allylic silanes. This enantio­selective reductive…”
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Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders by Hsiao, Elaine Y., McBride, Sara W., Hsien, Sophia, Sharon, Gil, Hyde, Embriette R., McCue, Tyler, Codelli, Julian A., Chow, Janet, Reisman, Sarah E., Petrosino, Joseph F., Patterson, Paul H., Mazmanian, Sarkis K.

“…Neurodevelopmental disorders, including autism spectrum disorder (ASD), are defined by core behavioral impairments; however, subsets of individuals display a…”
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A 15-step synthesis of (+)-ryanodol by Chuang, Kangway V., Xu, Chen, Reisman, Sarah E.

“…(+)-Ryanodine and (+)-ryanodol are complex diterpenoids that modulate intracellular calcium-ion release at ryanodine receptors, ion channels critical for…”
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Enantioselective Total Synthesis of (+)-Psiguadial B by Chapman, Lauren M, Beck, Jordan C, Wu, Linglin, Reisman, Sarah E

“…The first enantioselective total synthesis of the cytotoxic natural product (+)-psiguadial B is reported. Key features of the synthesis include (1) the…”
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Electrochemical Nozaki–Hiyama–Kishi Coupling: Scope, Applications, and Mechanism by Gao, Yang, Hill, David E, Hao, Wei, McNicholas, Brendon J, Vantourout, Julien C, Hadt, Ryan G, Reisman, Sarah E, Blackmond, Donna G, Baran, Phil S

“…One of the most oft-employed methods for C–C bond formation involving the coupling of vinyl-halides with aldehydes catalyzed by Ni and Cr (Nozaki–Hiyama–Kishi,…”
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Enantioselective Thiourea-Catalyzed Additions to Oxocarbenium Ions by Reisman, Sarah E, Doyle, Abigail G, Jacobsen, Eric N

“…Asymmetric, catalytic reactions of oxocarbenium ions are reported. Simple, chiral urea and thiourea derivatives are shown to catalyze the enantioselective…”
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Copper-Catalyzed Diastereoselective Arylation of Tryptophan Derivatives: Total Synthesis of (+)-Naseseazines A and B by Kieffer, Madeleine E, Chuang, Kangway V, Reisman, Sarah E

“…A copper-catalyzed arylation of tryptophan derivatives is reported. The reaction proceeds with high site- and diastereoselectivity to provide aryl…”
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Synthesis of Complex Diterpenes: Strategies Guided by Oxidation Pattern Analysis by Dibrell, Sara E, Tao, Yujia, Reisman, Sarah E

“…Conspectus With complex molecular architectures, intriguing oxidation patterns, and wide-ranging biological activities, diterpene natural products have greatly…”
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Cobalt-electrocatalytic HAT for functionalization of unsaturated C–C bonds by Gnaim, Samer, Bauer, Adriano, Zhang, Hai-Jun, Chen, Longrui, Gannett, Cara, Malapit, Christian A., Hill, David E., Vogt, David, Tang, Tianhua, Daley, Ryan A., Hao, Wei, Zeng, Rui, Quertenmont, Mathilde, Beck, Wesley D., Kandahari, Elya, Vantourout, Julien C., Echeverria, Pierre-Georges, Abruna, Hector D., Blackmond, Donna G., Minteer, Shelley D., Reisman, Sarah E., Sigman, Matthew S., Baran, Phil S.

“…The study and application of transition metal hydrides (TMHs) has been an active area of chemical research since the early 1960s 1 , for energy storage,…”
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Enantioselective Synthesis of Pyrroloindolines by a Formal [3 + 2] Cycloaddition Reaction by Repka, Lindsay M, Ni, Jane, Reisman, Sarah E

“…(R)-BINOL•SnCl4 was found to catalyze a formal [3 + 2] cycloaddition reaction between C(3)-substituted indoles and 2-amidoacrylates to provide…”
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Enantioselective Synthesis of Tryptophan Derivatives by a Tandem Friedel–Crafts Conjugate Addition/Asymmetric Protonation Reaction by Kieffer, Madeleine E, Repka, Lindsay M, Reisman, Sarah E

“…The tandem Friedel–Crafts conjugate addition/asymmetric protonation reaction between 2-substituted indoles and methyl 2-acetamidoacrylate is reported. The…”
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Evolution of a Strategy for the Enantioselective Total Synthesis of (+)-Psiguadial B by Chapman, Lauren M, Beck, Jordan C, Lacker, Caitlin R, Wu, Linglin, Reisman, Sarah E

“…(+)-Psiguadial B is a diformyl phloroglucinol mero­terpenoid that exhibits antiproliferative activity against the HepG2 human hepatoma cancer cell line. This…”
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Radical Deoxychlorination of Cesium Oxalates for the Synthesis of Alkyl Chlorides by Su, Justin Y, Grünenfelder, Denise C, Takeuchi, Kohei, Reisman, Sarah E

“…A radical deoxychlorination of cesium oxalates has been developed for the preparation of hindered secondary and tertiary alkyl chlorides. The reaction…”
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A Unified Strategy to ent-Kauranoid Natural Products: Total Syntheses of (−)-Trichorabdal A and (−)-Longikaurin E by Yeoman, John T. S, Mak, Victor W, Reisman, Sarah E

“…The first total syntheses of (−)-trichorabdal A and (−)-longikaurin E are reported. A unified synthetic strategy is employed that relies on a Pd-mediated…”
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A Concise Total Synthesis of (−)-Maoecrystal Z by Cha, Jacob Y, Yeoman, John T. S, Reisman, Sarah E

“…The first total synthesis of (−)-maoecrystal Z is described. The key steps of the synthesis include a diastereoselective TiIII-mediated reductive epoxide…”
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