Search Results - "Reisman, A."

Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver by Klaassen, Curtis D., Reisman, Scott A.

“…Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that positively regulates the basal and inducible expression of a large battery of…”
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Breaking bad: Fail-safes to the Hague Judgments Convention by Reisman, Diana A.A

“…The underlying and optimistic premise of the 2019 Hague Judgments Convention is that a state's transparent and impartial judicial system at the time that it…”
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A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction by Hare, Joshua M., MD, Traverse, Jay H., MD, Henry, Timothy D., MD, Dib, Nabil, MD, Strumpf, Robert K., MD, Schulman, Steven P., MD, Gerstenblith, Gary, MD, DeMaria, Anthony N., MD, Denktas, Ali E., MD, Gammon, Roger S., MD, Hermiller, James B., MD, Reisman, Mark A., MD, Schaer, Gary L., MD, Sherman, Warren, MD

“…Objectives Our aim was to investigate the safety and efficacy of intravenous allogeneic human mesenchymal stem cells (hMSCs) in patients with myocardial…”
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Introducing the “TCDD-Inducible AhR-Nrf2 Gene Battery” by Yeager, Ronnie L., Reisman, Scott A., Aleksunes, Lauren M., Klaassen, Curtis D.

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces genes via the transcription factor aryl hydrocarbon receptor (AhR), including Cyp1a1, NAD(P)H:quinone…”
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Automated layer segmentation of macular OCT images using dual-scale gradient information by Yang, Qi, Reisman, Charles A, Wang, Zhenguo, Fukuma, Yasufumi, Hangai, Masanori, Yoshimura, Nagahisa, Tomidokoro, Atsuo, Araie, Makoto, Raza, Ali S, Hood, Donald C, Chan, Kinpui

“…A novel automated boundary segmentation algorithm is proposed for fast and reliable quantification of nine intra-retinal boundaries in optical coherence…”
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Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study by Wunderink, Richard G., Niederman, Michael S., Kollef, Marin H., Shorr, Andrew F., Kunkel, Mark J., Baruch, Alice, McGee, William T., Reisman, Arlene, Chastre, Jean

“…Background. Post hoc analyses of clinical trial data suggested that linezolid may be more effective than vancomycin for treatment of methicillin-resistant…”
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Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes by Reisman, Scott A., Aleksunes, Lauren M., Klaassen, Curtis D.

“…Oleanolic acid is a plant-derived triterpenoid, which protects against various hepatotoxicants in rodents. In order to determine whether oleanolic acid…”
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Tissue distribution, hormonal regulation, ontogeny, diurnal expression, and induction of mouse cystine transporters Slc3a1 and Slc7a9 by Wu, Kai Connie, Reisman, Scott A, Klaassen, Curtis D

“…Slc7a11 (xCT) and Slc3a1 (rBAT) are cystine uptake transporters that maintain intracellular concentrations of cysteine, the rate-limiting amino acid in…”
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Bardoxolone Methyl Decreases Megalin and Activates Nrf2 in the Kidney by REISMAN, Scott A, CHERTOW, Glenn M, HEBBAR, Sudarshan, VAZIRI, Nosratola D, WARD, Keith W, MEYER, Colin J

“…Inflammation and oxidative stress are hallmarks and mediators of the progression of CKD. Bardoxolone methyl, a potent activator of the nuclear factor erythroid…”
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Optical Coherence Tomography in the UK Biobank Study - Rapid Automated Analysis of Retinal Thickness for Large Population-Based Studies by Keane, Pearse A, Grossi, Carlota M, Foster, Paul J, Yang, Qi, Reisman, Charles A, Chan, Kinpui, Peto, Tunde, Thomas, Dhanes, Patel, Praveen J

“…To describe an approach to the use of optical coherence tomography (OCT) imaging in large, population-based studies, including methods for OCT image…”
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CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes by Reisman, Scott A., Buckley, David B., Tanaka, Yuji, Klaassen, Curtis D.

“…CDDO-Im is a synthetic triterpenoid recently shown to induce cytoprotective genes through the Nrf2–Keap1 pathway, an important mechanism for the induction of…”
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The efficacy of voriconazole in the treatment of 192 fungal central nervous system infections: a retrospective analysis by Schwartz, S., Reisman, A., Troke, P. F.

“…Purpose The efficacy of voriconazole against fungal central nervous system (CNS) infections was examined retrospectively. Methods Voriconazole-treated patients…”
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Topical Application of the Synthetic Triterpenoid RTA 408 Protects Mice from Radiation-Induced Dermatitis by Reisman, Scott A., Lee, Chun-Yue I., Meyer, Colin J., Proksch, Joel W., Sonis, Stephen T., Ward, Keith W.

“…Free radicals produced during cancer radiotherapy often leads to dermatitis, with the insult ranging from mild erythema to moist desquamation and ulceration…”
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Apportioning Fault for Performance Corruption in Investment Arbitration by Reisman, Diana A A

“…International investment tribunals are frequently presented with the host state’s allegation that the foreign investor bribed a government official. In most of…”
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Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice by Aleksunes, Lauren M, Reisman, Scott A, Yeager, Ronnie L, Goedken, Michael J, Klaassen, Curtis D

“…The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) induces a battery of cytoprotective genes after oxidative stress. Nrf2 aids in…”
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Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis by Reisman, Scott A., Ferguson, Deborah A., Lee, Chun‐Yue I., Proksch, Joel W.

“…Omaveloxolone is a potent activator of Nrf2, a master transcriptional regulator of a multitude of cytoprotective functions, including antioxidative,…”
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Improving glaucoma detection using spatially correspondent clusters of damage and by combining standard automated perimetry and optical coherence tomography by Raza, Ali S, Zhang, Xian, De Moraes, Carlos G V, Reisman, Charles A, Liebmann, Jeffrey M, Ritch, Robert, Hood, Donald C

“…To improve the detection of glaucoma, techniques for assessing local patterns of damage and for combining structure and function were developed. Standard…”
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Altered Disposition of Acetaminophen in Nrf2-null and Keap1-knockdown Mice by Reisman, Scott A., Csanaky, Iván L., Aleksunes, Lauren M., Klaassen, Curtis D.

“…Acetaminophen (AA) is a widely used antipyretic drug that causes hepatotoxicity at high doses. Nuclear factor erythroid 2–related factor 2 (Nrf2) is a…”
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Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD by Lewis, James H., Jadoul, Michel, Block, Geoffrey A., Chin, Melanie P., Ferguson, Deborah A., Goldsberry, Angie, Meyer, Colin J., O’Grady, Megan, Pergola, Pablo E., Reisman, Scott A., Wigley, W. Christian, Chertow, Glenn M.

“…In a multinational placebo‐controlled phase III clinical trial in 2,185 patients with type 2 diabetes mellitus and stage 4 chronic kidney disease, treatment…”
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Impact of lorlatinib on patient-reported outcomes (PROs) in patients (Pts) with advanced ALK+ or ROS1+ non-small cell lung cancer (NSCLC) by Peters, S., Shaw, A.T., Besse, B., Felip, E., Solomon, B.J., Soo, R.A., Bearz, A., Gadgee, S.M., Lin, C.-C., Kao, S., Seto, T., Masters, E.T., Abbattista, A., Clancy, J.S., Thurm, H., Reisman, A., Camidge, D.R.

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